[PDF] Top 20 Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress
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Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress
... ER stress inhibitor), and thapsigargin (TG, ER stress agonist) were prepared in di- methyl sulfoxide (DMSO) and immediately diluted with cul- ture medium before the ...the cells reached 70-80% ... See full document
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Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes
... ER stress, activate the UPR and promote cell death in a great amount of cell types, such as hepatocytes [25][21] ...that palmitic acid causes obvious cell death in primary rat ...the palmitic ... See full document
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Original Article Polyenylphosphatidylcholine alleviates palmitic acid-induced apoptosis in HepG2 cells via inhibiting endoplasmic reticulum stress
... alleviate apoptosis induced by palmitic acid (PA), and explore the possible molecular mechanisms in HepG2 ...the cells with PA resulted in activation of Endoplasmic ... See full document
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Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure
... the endoplasmic reticulum (ER), which activates the unfolded protein response ...ER stress in tumor initiation and progression is ...ER stress, we applied tauroursodeoxycholic acid ... See full document
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Original Article Calcium homeostasis disruption and endoplasmic reticulum stress mediats ischemia/reperfusion-induced PC12 cells apoptosis
... tetraacetic acid (EGTA), Tritonx-100 and adenosine triphosphate (ATP) were pur- chased from VWR Life Science AMRESCO (So- lon, Ohio, USA), ATPase/GTPase activity assay kit was obtained from Sigma Chemical ... See full document
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Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors
... leukemic cells in ...leukemia cells and BTZ-resistant subclones to determine whether or not complementary mechanisms contribute to BTZ ...proteolytic stress related genes in drug resistant ... See full document
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A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress
... CA). Mouse monoclonal antibodies specific for both cytochrome C and mitochondria control protein, voltage-dependent anion channels (VDAC), were obtained from Abcam (Cambridge, MA, ...tetraacetic acid ... See full document
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Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells
... USA. Mouse monoclonal antibodies to cytochrome c, Bax and Bcl-2 and rabbit polyclonal antibody to Bcl-xL, and horseradish peroxidase (HRP) conjugated secondary antibodies were purchased from Abcam, Cambridge, ... See full document
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Astragaloside IV attenuates proteinuria in streptozotocin-induced diabetic nephropathy via the inhibition of endoplasmic reticulum stress
... The endoplasmic reticulum (ER) plays an important role in the folding and processing of newly synthesized ...Pathophysiological stress will lead to the accu- mulation of misfolded and unfolded ... See full document
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-induced apoptosis in PC12 cells by suppressing the expression of endoplasmic reticulum stress-related proteins
... Western blotting is a protein analysis technique which combines protein separation in an elec- tric field with immunochemical methods of pro- tein detection. It is used to identify, character- ize, quantify, and/or ... See full document
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<p>Ox-LDL Causes Endothelial Cell Injury Through ASK1/NLRP3-Mediated Inflammasome Activation via Endoplasmic Reticulum Stress</p>
... muscle cells, and inhibit choles- terol ef fl ux, resulting in large accumulations of cholesterol in foam ...that apoptosis of macrophage-derived foam cells occurs in the plaques of most patients with ... See full document
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<p>Dicerandrol B: a natural xanthone dimer induces apoptosis in cervical cancer HeLa cells through the endoplasmic reticulum stress and mitochondrial damage</p>
... and boiled for 10 minutes. Protein samples (30 µ g/sample) were subjected to 10% SDS-PAGE and electrotransferred to polyvinylidene difluoride membranes (Bio-Rad). Membranes were blocked with 5% nonfat dry milk in TBS ... See full document
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Tocotrienols induce endoplasmic reticulum stress and apoptosis in cervical cancer cells
... and apoptosis in human breast cancer cells (MDA-MB-231 and ...to apoptosis, also in tumor cells not expressing ...HeLa cells, a line of human cervical cancer cells void of any ... See full document
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Original Article ASK1 induces retinal microvascular endothelial cell apoptosis through ER stress-associated pathway
... ER stress- induced cell apoptosis, levels of ER stress markers were measured in HG cells treated with an inhibitor of endoplasmic ...of apoptosis, caspase-4, a molecule ... See full document
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Endoplasmic Reticulum Stress Caused by Lipoprotein Accumulation Suppresses Immunity against Bacterial Pathogens and Contributes to Immunosenescence
... changes induced by VIT protein accumulation in vit-2(ac3) animals compared to SJ4005 ...ER stress, gene ontology analysis for biological function of the upregulated genes showed enrichment in genes linked ... See full document
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Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy
... actin stress fibers. In the model group, intracellular actin stress fibers were collapsed or absent, leading to a polygonal cellular ...actin stress fibers and rescue of the podocytes shape (Figure ... See full document
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Autophagy activated via GRP78 to alleviate endoplasmic reticulum stress for cell survival in blue light-mediated damage of A2E-laden RPEs
... ER stress in A2E and blue light-treated ...ER stress have emerged as a novel autoph- agy inducer, which raises increasing attention ...ER stress in blue light-induced damaged of A2E- ... See full document
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Phagocytosis influences the intracellular survival of Mycobacterium smegmatis via the endoplasmic reticulum stress response
... ER stress-mediated apop- tosis ...ER stress response ...ER stress in macrophages infected with ...264.7 cells. The ROS level was significantly increased in RAW 264.7 cells infected with ... See full document
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<p>The Therapeutic Effect of Melatonin on GC by Inducing Cell Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress</p>
... be induced in cancer cells exposed to different perturbations, such as starvation, hypoxia, radiation, and growth factor ...cancer cells with melatonin enhances the creation of autophagosome ... See full document
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Original Article Protective effects of melatonin on lung and liver injuries in a rat model of acute sepsis
... Oxidative stress is one of the most significant factors in the pathogenesis of sepsis ...[36]. Melatonin exhibits both free radical scavenging and antioxidant proper- ...ties. Melatonin protects ... See full document
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