[PDF] Top 20 MELATONIN MODULATES MERCURY INDUCED OXIDATIVE STRESS IN RAT LIVER

... embodying melatonin efficiency to overcome oxidative stress are: 1) direct free radical scavenging actions, [10,11] 2) enhancing the activities of antioxidative enzymes, [12,13,14] 3) stimulating ... See full document

... of oxidative stress [ 9- 12]. In one study, QT protected rat brain from LPS-induced shock by attenuating lipid peroxidation and nitric oxide generation [ ...also modulates the activity ... See full document

... humans. Melatonin (MEL), a neurohormone produced by pineal gland, has been shown to be an effective antioxi- dant with free radical scavenging ...lung, liver and kidney tissues of rats as well as DNA damage ... See full document

... injury induced by bile duct ligation in male albino ...BDL induced marked alteration on renal functions as manifested by a significant increase in the kidney function markers, serum creatinine, urea and ... See full document

... the liver is a vital excretory organ for particular types of ...administered mercury was approximate ...of mercury upto 42% in sub-acute ...+2 induced serum biochemical changes responsible for ... See full document

... Abstract: Melatonin exhibits remarkable potential as an anti-inflammatory, antioxidative, and anti-apoptotic ...of melatonin on sepsis-induced lung and liver injuries in ...sepsis. ... See full document

... of melatonin in functioning to overcome oxidative stress relates to its direct free radical scaveng- ing actions [27,28], its ability to enhance the activities of number of antioxidative enzymes ... See full document

... Oxidative stress damages proteins by modification of its side chains depending on the nature of the amino acid ...to oxidative stress (Goon et ...to oxidative stress induction in ... See full document

... Oxidative stressplays a key roleinapoptosisof neural cells [1] which leads to cell damage in a variety of neurodegenerative diseases, including Alzheimer's disease and Parkinson's [2].Various types of chemical and ... See full document

... Liver is the principal detoxification organ and the po- tential impact of smoke on all of the antioxidative attrib- utes was almost similar to that of erythrocytes. The find- ing in this study showed that there ... See full document

... In this regard, Tagara ( Valeriana wallichii of family Valerianaceae), an ayurvedic drug that possesses protective effects on several aspects of brain and nervous conditions is chosen for the present study. It is well ... See full document

... Wedelia chinensis Merrill (Asteraceae) is a small much branched annual herb, commonly known as “Pilabhamgara” or “Bhringraj’in Hindi and is a reputed herbal medicine in both Ayurvedic and Unani system of medicine (2). ... See full document

... to oxidative stress because they are exposed to high oxygen tension and have a characteristic structural composition with polyunsaturated fatty acids in membrane, besides the presence of hemoglobin-bound ... See full document

... giving CCl4 along with olive oil (1:1; v/v) @ 2 ml CCl4 + 2 ml olive oil/kg body weight orally twice a week for four weeks (Doi et al.,1991). All groups has received hepatotoxic dose except healthy control group. Group ... See full document

... in liver and kidney of nicotine treated rats and attenuates the damaging ...smoke–induced oxidative damage and associated degenerative diseases (Panda et ...the liver from oxidant damage ... See full document

... of rat osteoblasts with 1, 10, 100, and 1000 µ g/mL nWEG for 24, 48, or 72 hours did not change cell morphologies or cell ...to rat osteoblasts. In parallel, when primary rat osteoblasts were ... See full document

... STZ induced diabetic rats Thermal Hyperalgesia tests were performed after the administration of STZ in the albino wistar rats, Thermal Allodynia and Cold Allodynia tests were ...wistar Rat of control group ... See full document

... Oxidative stress has been accepted as a major molecular mechanism in CCl 4 -induced acute liver injury, which is responsible for cell mem- brane damage and the consequent release of marker ... See full document

... Effect of aflatoxin and Cynodon dactylon leaf extract either alone or in different combination on hematological variables in albino rats are illustrated in table 2. Supplementation of aflatoxin led to significant fall ... See full document

... Aluminum has been implicated in human neurodegenerative diseases like Alzheimer’s. Possible mechanisms of aluminum induced neurotoxicity have been related to cell damage via free radical production. Increased ... See full document