[PDF] Top 20 T cell metagene predicts a favorable prognosis in estrogen receptor negative and HER2 positive breast cancers
Has 10000 "T cell metagene predicts a favorable prognosis in estrogen receptor negative and HER2 positive breast cancers" found on our website. Below are the top 20 most common "T cell metagene predicts a favorable prognosis in estrogen receptor negative and HER2 positive breast cancers".
T cell metagene predicts a favorable prognosis in estrogen receptor negative and HER2 positive breast cancers
... of breast cancer patients or whether efficacy of specific anticancer treatment approaches depends on the existence of defined tumor host factors and are therefore predictive in some way should be ... See full document
13
Prognostic Significance of Progesterone Receptor Expression in Estrogen-Receptor Positive, HER2-Negative, Node-Negative Invasive Breast Cancer With a Low Ki-67 Labeling Index
... positive breast cancers are in practice classified into luminal A (LA)- like subtype and luminal B (LB)-like subtype with or without HER2 ...worse prognosis compared with the LA-like ... See full document
7
Basal like phenotype is not associated with patient survival in estrogen receptor negative breast cancers
... responsiveness could be confirmed or if treatments specifi- cally targeting basal-like tumors were developed. In addition to prognostic assessments, the microarray-based gene data may be more relevant for revealing the ... See full document
10
Management of hormone receptor positive human epidermal receptor 2 negative advanced or metastatic breast cancers
... hormone-receptor positive (HR+), human epidermal receptor 2 negative (HER2−) advanced or metastatic breast cancer (A/MBC) according to the European Society of Medical Oncology ... See full document
10
Molecular essence and endocrine responsiveness of estrogen receptor-negative, progesterone receptor-positive, and HER2-negative breast cancer
... functional estrogen-responsive pathway and improves the response to tamoxifen ...detect positive ER even after re-assessment by ...When estrogen binds cell surface ER, membrane-initiated ... See full document
11
Genomic Landscape and Endocrine-Resistant Subgroup in Estrogen Receptor-Positive, Progesterone Receptor-Negative, and HER2-Negative Breast Cancer
... human cancers, such as lung cancer [42, 43], colorectal cancer [44] and head and neck squamous cell carcinoma ...in breast cancer cell lines could promote cell proliferation and ... See full document
14
Different mechanisms for resistance to trastuzumab versus lapatinib in HER2 positive breast cancers role of estrogen receptor and HER2 reactivation
... the HER2 pathway was observed during the late phase of acquisition of ...reduced cell death in LR cells at the early stage, acting as a transitional ...HER receptor and ligand expression occurred, ... See full document
19
Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15
... ER(-) HER2(3+) AR(+) or ER(-) HER2(-) AR(+) may be MA tumors but it is likely that other MA tumors will be missed with this definition centered on AR ...ER(-) breast tumors, a composite signature ... See full document
11
Estrogen receptor variants in ER-positive basal-type breast cancers responding to therapy like ER-negative breast cancers
... negative cancers, and others showing an intermediate prognosis compared to ER-negative and ER-positive ...+ HER2−/Luminal patients (34 ...ER+/Basal breast cancers ... See full document
8
Estrogen receptor positive breast cancers and their association with environmental factors
... of cancers may also have occurred; again, this error most likely biased our results towards the ...of breast cancer in a county apply to the ...ER+ breast cancer at the county level may also transfer ... See full document
8
Characterization and prognosis of estrogen receptor positive/progesterone receptor negative male breast cancer: a population based study
... Interestingly, chemotherapy was confirmed an inde- pendent prognostic factor in the multivariate Cox ana- lyses of OS but did not reach significance with this test in BCSS, neither in ER+/PR+ nor ER+/PR − cohort, as ... See full document
8
Molecular portraits and trastuzumab responsiveness of estrogen receptor-positive, progesterone receptor-positive, and HER2-positive breast cancer
... of HER2-positive breast cancers from the TCGA dataset according to ER and PR ...162 HER2-positive samples are classified into four groups according to the IHC-based ER and PR ... See full document
11
The origins of estrogen receptor alpha positive and estrogen receptor alpha negative human breast cancer
... ER- negative DCIS, which both represent about 25% of their respective categories and resemble each other in many other ...higher-grade/ER- negative DCIS may evolve from lower-grade DCIS as they accumulate ... See full document
6
Paralemmin-1 is over-expressed in estrogen-receptor positive breast cancers
... Phosphorylation and mRNA splicing of paralemmin-1 is tissue-specific, developmentally regulated and contri- butes to the electrophoretic heterogeneity frequently seen on Western Blots. Amino acids 154–230 of para- ... See full document
10
A Therapeutic Target for Hormone-independent Estrogen Receptor-positive Breast Cancers
... Background: The action of the steroid hormone estradiol (E2) is mediated via interaction with a specific receptor (ER) that initiates a series of events downstream, leading to the modulation of hormone-responsive ... See full document
9
Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers
... established cell line model of ER-positive human breast cancer subjected to conditions simulating loss of ER function and oxidative stress, we identified a signature set of 62 unique Ox-E/ER genes, ... See full document
17
Estrogen receptor negative/progesterone receptor positive breast cancer is not a reproducible subtype
... ER-/PR+ breast cancer is not a reproducible ...ER+ breast cancer is also not ...ER+ breast cancer; however, it is important to note that testing for PR expression currently provides no clinically ... See full document
13
Estrogen receptor negative/progesterone receptor positive breast cancer is not a reproducible subtype
... ER+ breast cancer (Figure ...3,666 cancers as ER+ (2,505; 68%) or ER- (1,161; 32%) based on mRNA expression ...ER+ breast cancer (PGR is more variable than approximately 98% of the genes in the ... See full document
14
Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1 associated breast cancers
... ductal cancers with higher proliferative rates, and a greater propensity to express basal ...BRCA1 breast cancers, such as poly(ADP-ribose) polymerase (PARP) inhibitors and cisplatin [47,48], are ... See full document
13
Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers
... hormone- receptor-positive early breast cancer that compares 5 years of adjuvant tamoxifen or letrozole monotherapy or sequential treatment with 2 years of one of these agents followed by 3 years of ... See full document
9
Related subjects