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[PDF] Top 20 Molecular Genetic Study of the Interaction of Sindbis Virus E2 with Ross River Virus E1 for Virus Budding

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Molecular Genetic Study of the Interaction of Sindbis Virus E2 with Ross River Virus E1 for Virus Budding

Molecular Genetic Study of the Interaction of Sindbis Virus E2 with Ross River Virus E1 for Virus Budding

... for budding. The block to budding cannot lie in the interaction of the glycoprotein tails and the nucleocapsid per se, because only E2 has a significant cytoplasmic tail required for ... See full document

6

Adaptive Mutations in Sindbis Virus E2 and Ross River Virus E1 That Allow Efficient Budding of Chimeric Viruses

Adaptive Mutations in Sindbis Virus E2 and Ross River Virus E1 That Allow Efficient Budding of Chimeric Viruses

... SIN E2 and RR E1 that result in the production of much more virus much more ...the interaction of one or the other with, for example, cellular receptors or other cellular ...that virus ... See full document

8

A Tyrosine-to-Histidine Switch at Position 18 of the Ross River Virus E2 Glycoprotein Is a Determinant of Virus Fitness in Disparate Hosts

A Tyrosine-to-Histidine Switch at Position 18 of the Ross River Virus E2 Glycoprotein Is a Determinant of Virus Fitness in Disparate Hosts

... the Sindbis virus and CHIKV E2 proteins were solved (33, 34), allowing for the accurate placement of RRV E2 position 18 within the context of the alphavirus E1-E2 heterodimer ... See full document

15

Interactions between the Transmembrane Segments of the Alphavirus E1 and E2 Proteins Play a Role in Virus Budding and Fusion

Interactions between the Transmembrane Segments of the Alphavirus E1 and E2 Proteins Play a Role in Virus Budding and Fusion

... the E1 and E2 subunits contribute a major regulatory mechanism for the viral fusion ...of E1 is suppressed by a very stable subunit interaction ...where virus budding occurs (6). ... See full document

10

Interactions of the Cytoplasmic Domain of Sindbis Virus E2 with Nucleocapsid Cores Promote Alphavirus Budding

Interactions of the Cytoplasmic Domain of Sindbis Virus E2 with Nucleocapsid Cores Promote Alphavirus Budding

... this study from molec- ular genetic and biochemical experiments, we propose that there are three major interactions involving cdE2 that occur at various cellular compartments at three different stages of ... See full document

15

The Surface Conformation of Sindbis Virus Glycoproteins E1 and E2 at Neutral and Low pH, as Determined by Mass Spectrometry-Based Mapping

The Surface Conformation of Sindbis Virus Glycoproteins E1 and E2 at Neutral and Low pH, as Determined by Mass Spectrometry-Based Mapping

... the E1 and E2 glycoproteins in the spike complex remains ...while E1 and E2 have similar numbers of tyrosines in their ectodomains, the tyrosines in E2 are more accessible for labeling ... See full document

12

Genetic heterogeneity among isolates of Ross River virus from different geographical regions.

Genetic heterogeneity among isolates of Ross River virus from different geographical regions.

... The aim of this study was to use RNase T1 mapping to examine the genetic relatedness of multiple isolates of RR virus from different geographical regions and to determine whether i the v[r] ... See full document

10

Molecular basis of Sindbis virus neurovirulence in mice.

Molecular basis of Sindbis virus neurovirulence in mice.

... These recombinant viruses allowed us to test the importance of each amino acid difference between the various strains for neurovirulence in weanling and suckling mice.. Glycoproteins E2 [r] ... See full document

8

A model for the dynamics of Ross River Virus in the Australian environment

A model for the dynamics of Ross River Virus in the Australian environment

... A linearized solution has been derived for the seasonally forced model, assuming that the forced oscillations occur as small perturbations to the second, more complex, equilibrium population distribution. Following ... See full document

20

Expression and Evaluation of Chikungunya Virus E1 and E2 Envelope Proteins for Serodiagnosis of Chikungunya Virus Infection

Expression and Evaluation of Chikungunya Virus E1 and E2 Envelope Proteins for Serodiagnosis of Chikungunya Virus Infection

... Chikungunya virus (CHIKV) causes endemic or epidemic outbreaks of CHIKV fever, which is a mosquitoe- transmitted viral disease in Africa, India, South-East Asia, and recently Southern ...whole virus ... See full document

8

Molecular Characterization of Feline Immunodeficiency Virus Budding

Molecular Characterization of Feline Immunodeficiency Virus Budding

... immunodeficiency virus (FIV) is an important model system for studying human immunodeficiency virus type 1 (HIV-1) infection due to numerous similarities in pathogenesis induced by these two ...many ... See full document

14

Carbohydrate Structure of Sindbis Virus Glycoprotein E2 from Virus Grown in Hamster and Chicken Cells

Carbohydrate Structure of Sindbis Virus Glycoprotein E2 from Virus Grown in Hamster and Chicken Cells

... Thus, Sindbis glycoprotein E2 acquires a complex acidic oligosaccharide and a high-mannose oligosaccharide when grown in BHK and chicken cells, whereas the vesicular stomatitis virus gly[r] ... See full document

9

Interaction of Sindbis virus with liposomal model membranes.

Interaction of Sindbis virus with liposomal model membranes.

... The curve of liposomes lacking phosphatidylethanolamine is an average of five experiments with samples from four different virus preparations, including the three preparations used in th[r] ... See full document

7

Interaction of Sindbis virus glycoproteins during morphogenesis.

Interaction of Sindbis virus glycoproteins during morphogenesis.

... 778 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest In cells infected with the Sindbis temperature-sensitive mutants ts-23 and ts10 complementation group D, which conta[r] ... See full document

10

Probing the Early Temporal and Spatial Interaction of the Sindbis Virus Capsid and E2 Proteins with Reverse Genetics

Probing the Early Temporal and Spatial Interaction of the Sindbis Virus Capsid and E2 Proteins with Reverse Genetics

... and E1, which are initially translated from a subgenomic message as a polyprotein ...and E1, the envelope proteins, and 6K, a small membrane-resident protein whose function in the virus life cycle ... See full document

12

Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA.

Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA.

... the virus mem- brane proteins from a second helper ...infectious virus genome would then require several independent crossover ...alphavirus, Ross River virus, and the second was to ... See full document

11

Sindbis Virus Conformational Changes Induced by a Neutralizing Anti-E1 Monoclonal Antibody

Sindbis Virus Conformational Changes Induced by a Neutralizing Anti-E1 Monoclonal Antibody

... these virus-antibody complexes suggested a mechanism of neutralization and determined the location of the E2 epitopes on the surfaces of virions ...that study, Smith et al. suggested that ... See full document

11

Effect of E2 envelope glycoprotein cytoplasmic domain mutations on Sindbis virus pathogenesis.

Effect of E2 envelope glycoprotein cytoplasmic domain mutations on Sindbis virus pathogenesis.

... aberrant virus particles that are not capable of producing ...undefined interaction be- tween the E2 cytoplasmic tail and mouse brain cells that is necessary for the establishment of persistent ... See full document

6

Characterization of Ross River Virus Tropism and Virus-Induced Inflammation in a Mouse Model of Viral Arthritis and Myositis

Characterization of Ross River Virus Tropism and Virus-Induced Inflammation in a Mouse Model of Viral Arthritis and Myositis

... Identification of inflammatory infiltrates in vivo. To begin to identify mechanisms involved in RRV-induced inflamma- tion and pathology, the composition of inflammatory infiltrates within the hind limb skeletal muscle ... See full document

13

Genome of Sindbis Virus

Genome of Sindbis Virus

... In light of the foregoing, it is difficult to understand how Sindbis RNA as well as WEE RNA sedimented at rates similar to that of 28S rRNA or viral 26S RNA in sucrose gradients prepared[r] ... See full document

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