[PDF] Top 20 Monozygotic Twins Discordant for ROHHAD Phenotype

... for ROHHAD and can range from overnight noninvasive (mask) positive-pressure ventilation (NPPV) to continuous mechanical ven- tilation via ...with ROHHAD develop tumors ... See full document

... MZ twins discordant for ASD and autism-related traits using a genome-wide ...all discordant twin pairs for each diagnostic category and others specific to one or two twin pairs, or one or two ... See full document

... one of these measures. There was a varying degree of over- lap between the OTUs identified through the regression analyses, with only two OTUs significantly associated with all three obesity associated measurements. It ... See full document

... genes. Monozygotic (MZ) twin pairs are long thought to share 100% of their genomic ...clinically discordant MZ ...pairs discordant for autism spectrum disorder (ASD) using the Illumina Infinium ... See full document

... 35 ROHHAD patients in whom the clinical diagnosis was confirmed were included in this cohort for genetic investigation (Table ...other ROHHAD patients were included in the secondary ex- ome and Sanger ... See full document

... targeting monozygotic twins discordant for categorical or dimensional autistic and inattentive/hyperactive-impulsive phenotypes as well as other neurodevelopmental disorders, and typically developing ... See full document

... the discordant phenotype might have resulted from alter- ations in DNA methylation ...MZ twins share a single uterus, they might be exposed to different in- trauterine environments such as uneven ... See full document

... 17q21 specific to childhood-onset disease [11]. Identified variants, however, account for only a small proportion of the estimated heritability [1, 11, 12]. Epidemiological research also highlights associations between ... See full document

... Monozygotic twins with a discordant clinical phenotype provide a unique opportunity to evaluate the contribu- tion of environmental factors against the identical gen- etic background ...in ... See full document

... behavioural phenotype (Levy and Reid, 1976), nor a single underlying causal ...adult monozygotic twins strongly discordant for writing hand ... See full document

... Downstream GO enrichment analysis on the 500 top- ranked diurnal preference associated DMPs identified a number of FDR significant over-represented terms, includ- ing cell adhesion processes and calcium ion binding. ... See full document

... DNA microarray study was carried out to find out rea- son for discordance using HumanCytoSNP-12 BeadChip (Illumina). The DNA was extracted from 250 uL of stored EDTA blood sample using Qiagen micro kit. The DNA quality ... See full document

... of monozygotic twins discordant for ...that monozygotic twins differ for some CNVs, a difference that may be acquired during their somatic ...between monozygotic twins may ... See full document

... of discordant MZ twins, focusing on ...using discordant MZ twins offers the opportunity to control for many potential confounders encountered in general population studies, such as differences ... See full document

... complex phenotype, and the exact contribution of genetic and epigenetic variation to it, and extent of its shared effects with late-onset diseases, remains largely ...(monochorionic: twins that share a ... See full document

... the discordant phenotypes of the respective ...MZ twins discordant for psoriasis or primary biliary cirrhosis (Gervin et ...sclerosis discordant MZ twin pairs (Baranzini et ... See full document

... baseline to Year 6, and with the exception of two partici- pants, all other participants with longitudinal samples paired with self when grouped by unsupervised hierarch- ical clustering. When a large number of random ... See full document

... ing is important—either as a risk factor for AN or as an early warning sign or prodrome of the illness. Vigilance for early dieting by parents, schools, and health care professionals may assist with detecting and ... See full document

... male monozygotic twins with strabismus also presented the same clinical ...in monozygotic twins with unaffected parents and dizygotic sibling manifesting similar genetic pattern, reinforcing ... See full document

... This study is aimed at assessing putative CNV calls made using the Affymetrix Human SNP 6.0 Array using four CNV calling programs: PennCNV (Wang et al., 2007), Affymetrix Genotyping Console (Korn et al., 2008), Partek ... See full document