[PDF] Top 20 Multiple human herpesvirus-8 infection
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Multiple human herpesvirus-8 infection
... passes the highly variable V1 region [11] (hereafter referred to as “K1/V1”), spanning positions 366–577, was amplified from sample extracts by use of nested PCR, as described elsewhere [3] (K1/V1 position assignments ... See full document
12
Effective Human Herpesvirus 8 Infection of Human Umbilical Vein Endothelial Cells by Cell-Mediated Transmission
... of human herpesvirus 8 (HHV-8) to human cells in vitro has been reported to be difficult, if not ...Primary human umbilical vein endothelial cells (HUVECs) were cocultured with ... See full document
6
Persistent Infection of Epstein-Barr Virus-Positive B Lymphocytes by Human Herpesvirus 8
... (KS), human herpesvirus 8 (HHV-8) can invariably be detected in KS tumor tissue and, at a lower frequency, in prostate tissue and peripheral blood B ...lytic infection are found ... See full document
7
Long-Term Infection and Transformation of Dermal Microvascular Endothelial Cells by Human Herpesvirus 8
... Human herpesvirus 8 (HHV8) infects Kaposi’s sarcoma (KS) spindle cells in situ, as well as the lesional endothelial cells considered to be spindle cell ...that infection of endothelial and ... See full document
11
Lipid Rafts of Primary Endothelial Cells Are Essential for Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8-Induced Phosphatidylinositol 3-Kinase and RhoA-GTPases Critical for Microtubule Dynamics and Nuclear Delivery of Viral DNA but Dispensable for Binding and Entry
... and infection, and instead we observed the dramatic decrease in infected nucleus- associated viral ...cell infection by herpesviruses is a complex multistep event, which includes the initial attachment to ... See full document
19
Activation of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Lytic Replication by Human Cytomegalovirus
... HCMV infection, demonstrat- ing typical CPE ...HCMV infection, were reacted with MAb 11D1 for the detection of the KSHV lytic ORF 59 ...lane 8, ... See full document
9
K-bZIP of Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 (KSHV/HHV-8) Binds KSHV/HHV-8 Rta and Represses Rta-Mediated Transactivation
... (bZIP) domain at the carboxyl terminus (17). K-bZIP derives its sequence from three coding exons and one untranslated exon via splicing of the K8 ORF mRNA (17). While K8 ORF mRNA can yield multiple gene products ... See full document
7
Human herpesvirus 8 and new pathological associations
... Oral lesions play an important role in the diagnosis and in the staging of the HTV disease. The presence of lesions such as oral candidosis and oral hairy leukoplakia (OHL) are well recognised indicators of advancing HTV ... See full document
234
Four-Antigen Mixture Containing V-Cyclin for Serological Screening of Human Herpesvirus 8 Infection
... useful antigen in the LIPS format, identifying 94% (86/91) of the KS-positive samples with 100% specificity. While not sta- tistically significant, ROC comparisons of LIPS and ELISA in the detection of anti-K8.1 ... See full document
7
High Prevalence of Multiple Human Herpesviruses in Saliva from Human Immunodeficiency Virus Infected Persons in the Era of Highly Active Antiretroviral Therapy
... (HIV) infection is associated with an increased risk for human herpesvi- ruses (HHVs) and their related ...(EBV), human herpesvirus 8 (HHV-8), cytomegalovirus (CMV), and herpes ... See full document
7
Transcription Program of Human Herpesvirus 8 (Kaposi's Sarcoma-Associated Herpesvirus)
... 3, 8, 10, 12, 24, 36, 48, 72, and 96 hpi to encompass the complete lytic cycle (29, ...during infection, different viral genes can be seen to increase (red spots) and decrease (green to light-green spots) ... See full document
11
Carboxy Terminus of Human Herpesvirus 8 Latency-Associated Nuclear Antigen Mediates Dimerization, Transcriptional Repression, and Targeting to Nuclear Bodies
... Although the role of LANA during HHV-8 latency and tumor formation is poorly understood, there are interesting functional parallels to the EBNA-1 protein of Epstein-Barr virus. LANA and EBNA-1 are unrelated by ... See full document
9
Highly Sensitive Assay for Human Herpesvirus 8 Antibodies That Uses a Multiple Antigenic Peptide Derived from Open Reading Frame K8 1
... The one-letter amino acid symbols recommended by the IUPAC-IUB Joint Commission on Biochemical Nomenclature are used throughout this report (14). PEIA. Published procedures for the peptide EIA (PEIA), with slight modifi- ... See full document
5
Distinct p53, p53:LANA, and LANA Complexes in Kaposi's Sarcoma-Associated Herpesvirus Lymphomas
... for human telomerase ...latent infection of B cells with KSHV has consistently failed to bring about a fully transformed phenotype (18, 46, ...of multiple LANA complexes, one each for the ... See full document
11
Human herpesvirus 8 – A novel human pathogen
... several human diseases and malignancies, including MCD with its characteristic plas- macytosis and ...the human homo- logue [63]. This viral gene is unique to HHV-8 among the other gammaherpesviruses ... See full document
32
Herpesvirus Infections in Organ Transplant Recipients
... CMV. Human cytomegalovirus (CMV; human herpesvirus 5) is a member of the betaherpesvirus ...the infection rate increases with age ...symptomatic infection occurring in 20 to 60% of all ... See full document
7
Human cytomegalovirus, human herpesvirus 6 and human herpesvirus 7 infection of the immunocompromised host
... Whilst undoubtedly useful in certain circumstances, the classification of herpesviruses on biological characteristics is subjective and does produce anomalies; for example Epstein- Barr virus, a gamma-herpesvirus, ... See full document
215
Patterns of human herpesvirus-8 oral shedding among diverse cohorts of human herpesvirus-8 seropositive persons
... Human herpesvirus-8 (HHV-8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), establishes life- long latent infection, punctuated with periods of lytic replication at ... See full document
9
Kaposi's Sarcoma-Associated Herpesvirus Induces Sustained NF-κB Activation during De Novo Infection of Primary Human Dermal Microvascular Endothelial Cells That Is Essential for Viral Gene Expression
... KSHV infection of primary endothelial cells leads to the increased secretion of human cytokines, chemokines, and growth factors via the activation of NF- ...KSHV infection at all three time points, ... See full document
20
Prevalence of human herpesvirus 8 infection in systemic lupus erythematosus
... HHV-8 infection a critical factor in the pathogenesis of SLE or a passenger virus? Whether HHV-8 can trigger and/or exacerbate SLE as its gammaherpesvirus homolo- gous EBV does? Is there other ... See full document
5
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