• No results found

[PDF] Top 20 Neuroinflammation and MMPs: potential therapeutic targets in neonatal hypoxic-ischemic injury

Has 10000 "Neuroinflammation and MMPs: potential therapeutic targets in neonatal hypoxic-ischemic injury" found on our website. Below are the top 20 most common "Neuroinflammation and MMPs: potential therapeutic targets in neonatal hypoxic-ischemic injury".

Neuroinflammation and MMPs: potential therapeutic targets in neonatal hypoxic-ischemic injury

Neuroinflammation and MMPs: potential therapeutic targets in neonatal hypoxic-ischemic injury

... In contrast to these findings, evidence supporting a neuro- protective role of microglial activation and cytokine sign- aling has raised issues as to the precise role of this signaling in various injury models. ... See full document

7

The potential of erythropoietin to treat asphyxia in newborns

The potential of erythropoietin to treat asphyxia in newborns

... after neonatal hypoxic-ischemic brain injury, we can develop new neuroprotective strategies that promote or inhibit specific ...following injury, it is possible that, ultimately, a ... See full document

13

Neonatal Hypoxic-Ischemic Brain Injury: Apoptotic and Non-Apoptotic Cell Death

Neonatal Hypoxic-Ischemic Brain Injury: Apoptotic and Non-Apoptotic Cell Death

... into therapeutic targeting of necrotic cell death, due to the lack of identified markers and regulatory ...new therapeutic targets to reduce neonatal HI brain ...with neonatal HI that ... See full document

6

Inhibition of miRNA-210 reverses nicotine-induced brain hypoxic-ischemic injury in neonatal rats

Inhibition of miRNA-210 reverses nicotine-induced brain hypoxic-ischemic injury in neonatal rats

... to hypoxic-ischemic (HI) injury in neonatal rats through up-regulation of miR-210 expression in the developing ...brain injury were performed in 10-day-old ...decreased neonatal ... See full document

9

Individualized perfusion targets in hypoxic ischemic brain injury after cardiac arrest

Individualized perfusion targets in hypoxic ischemic brain injury after cardiac arrest

... intriguing therapeutic strategy, several lim- itations need to be ...MAP targets must be weighed against the potential benefits of improved cerebral perfusion and ... See full document

5

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic ischemic brain injury

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic ischemic brain injury

... brain injury in the perinatal period is H-I. This kind of injury is thought to be the single largest con- tributor to static encephalopathies in children and can result in mental impairment, seizures, and ... See full document

9

Potential biomarkers for neuroinflammation and neurodegeneration at short and long term after neonatal hypoxic-ischemic insult in rat

Potential biomarkers for neuroinflammation and neurodegeneration at short and long term after neonatal hypoxic-ischemic insult in rat

... During the chronic phase, i.e., 4 weeks after the HI injury, most of the genes were still upregulated in the ipsilateral vs contralateral hemisphere in both male and fe- male rats. These findings might suggest ... See full document

18

TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury

TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury

... brain injury. Clinically, acute ischemic stroke patients are given therapies after symptom ...brain injury in an adult mouse model of middle cerebral artery occlusion model, with a thera- peutic ... See full document

13

Magnetic resonance spectroscopy as a prognostic marker in neonatal hypoxic-ischemic encephalopathy: a study protocol for an individual patient data meta-analysis

Magnetic resonance spectroscopy as a prognostic marker in neonatal hypoxic-ischemic encephalopathy: a study protocol for an individual patient data meta-analysis

... Hypoxic-ischemic encephalopathy (HIE) in the newborn is associated with brain energy metabolism disturbances that can be quantified in vivo by 1 H (proton) magnetic resonance spectroscopy (MRS) [1,2]. A ... See full document

6

TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain

TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain

... matter injury of the immature rat brain ...in neuroinflammation and in the cells of the neurovascular unit remains ...brain injury in premature infants [1,17,18], TNF-α and JNK activation precede ... See full document

15

Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury

Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury

... focal ischemic injury allowing for comparison between an HI (ipsilateral) and hypoxia alone (contralateral) hemisphere ...humidified hypoxic gas mixture (10% oxygen in nitrogen, 36 °C) for 75 ...or ... See full document

18

Granulocyte Stimulating Factor Attenuates Hypoxic ischemic Brain Injury by Inhibiting Apoptosis in Neonatal Rats

Granulocyte Stimulating Factor Attenuates Hypoxic ischemic Brain Injury by Inhibiting Apoptosis in Neonatal Rats

... The experimental protocols described herein were reviewed and approved by the Animal Care and Use Committee of Samsung Biomedical Research Center, Seoul, Korea. This study was performed in accordance with the ... See full document

7

Original Article Neuroprotective and regenerative effects of melatonin on hypoxic-ischemic brain injury in neonatal rats

Original Article Neuroprotective and regenerative effects of melatonin on hypoxic-ischemic brain injury in neonatal rats

... brain injury area after ischemia and hypoxia, apoptosis of cortical cells in the ischemic hypoxic injury area was evaluated by ...The ischemic-hypoxic rats without tre- atment ... See full document

9

Hypothermia: A Neuroprotective Therapy for Neonatal Hypoxic-Ischemic Encephalopathy

Hypothermia: A Neuroprotective Therapy for Neonatal Hypoxic-Ischemic Encephalopathy

... hood. It was widely adopted, although the duration of ischemia that could be sustained without incurring per- manent central nervous system injury was not estab- lished. The heterogeneity of lesions and lack of ... See full document

9

Antepartum and Intrapartum Factors Preceding Neonatal Hypoxic-Ischemic Encephalopathy

Antepartum and Intrapartum Factors Preceding Neonatal Hypoxic-Ischemic Encephalopathy

... In this case-control study we found that only 1 antepartum factor but multiple intrapartum factors were independ- ently associated with the development of neonatal HIE. Although some ante- partum factors appeared ... See full document

10

Metalloproteinases and neurodegenerative diseases: pathophysiological and therapeutic perspectives

Metalloproteinases and neurodegenerative diseases: pathophysiological and therapeutic perspectives

... an injury, and once activated, they change shape and secrete primarily ...an injury, multiple MMPs are released into the interstitial space, where they act on many structural proteins and alter cell ... See full document

12

Grape Seed Proanthocyanidin Extract Adjusts NeuN/GFAP in a Murine Model of Neonatal Hypoxic-ischemic Brain Injury

Grape Seed Proanthocyanidin Extract Adjusts NeuN/GFAP in a Murine Model of Neonatal Hypoxic-ischemic Brain Injury

... of neonatal hypoxic ischemic encephalopathy (HIE), we investigated the changes in neuronal cells and astrocytes after pre-treatment with ...a potential drug for the treatment of HIE and can ... See full document

5

Original Article The effect and mechanism of UCH-L1 inhibitor LDN-57444 on hypoxic/ischemic injury in neonatal rats

Original Article The effect and mechanism of UCH-L1 inhibitor LDN-57444 on hypoxic/ischemic injury in neonatal rats

... of neonatal, and its com- mon pathogenesis is intrauterine fetal distress, which can be caused by various of causes such as umbilical cord around the neck, abnormality in amniotic fluid and so ...of ... See full document

7

Prevalence, severity and early outcomes of hypoxic ischemic encephalopathy among newborns at a tertiary hospital, in northern Tanzania

Prevalence, severity and early outcomes of hypoxic ischemic encephalopathy among newborns at a tertiary hospital, in northern Tanzania

... The neonatal ward admits a considerable number of neonates per year with most of those deliv- ered being from within the ...or therapeutic cooling/hypothermia is not available at this set ... See full document

6

Cerebellar Vermian Atrophy after Neonatal Hypoxic Ischemic Encephalopathy

Cerebellar Vermian Atrophy after Neonatal Hypoxic Ischemic Encephalopathy

... This retrospective study was performed at a tertiary care children’s hospital. CT scans obtained at our institution of neonates with clinically diagnosed hypoxic-ischemic encepha- lopathy during a period of ... See full document

8

Show all 10000 documents...