[PDF] Top 20 New approaches to nitrogen heterocycles via radical cyclisations
Has 10000 "New approaches to nitrogen heterocycles via radical cyclisations" found on our website. Below are the top 20 most common "New approaches to nitrogen heterocycles via radical cyclisations".
New approaches to nitrogen heterocycles via radical cyclisations
... 32 Quayle has successfully synthesised of a number of benzannulated products using copper complexes of ligands 84 and 85. 92,98 Initially the cyclisation of ester 79 with 5 mol% Cu(85)Cl in toluene afforded lactone 83 in ... See full document
293
Synthesis of nitrogen heterocycles via amidyl radical cyclisations
... amidyl radical cyclisations and the effect of the nitrogen substituent on the ...amidyl radical cyclisations are likely to be much flatter than the hex-5-enyl analogues due to the ... See full document
257
A radical approach to nitrogen heterocycles
... metal-catalysed radical cyclisations have received considerable attention in organic ...the cyclisations of allyl trichloroacetate by copper catalysts have been reported by Nagashima and ... See full document
265
Oxime derivatives : versatile reagents for radical mediated syntheses of heterocycles
... with radical chemistry and the ability of radicals to perform intramolecular cyclisations, together with the virtues of MAOS make the combination of both an extremely useful tool for organic and medicinal ... See full document
269
Copper (I) mediated radical cyclisation novel approaches to nitrogen heterocycles
... Tandem radical cyclisation reactions have been catalysed using copper I chlorideibipy.19 For example, reaction of trichloroamide 38 with this catalyst at 40°C gave the diastereomeric bic[r] ... See full document
347
Total Synthesis of the Synoxazolidinone Family of Natural Products and Novel Approaches for the Construction of Nitrogen and Oxygen Containing Heterocycles.
... incorporate nitrogen and oxygen-containing heterocycles as their core structural ...of new synthetic methods for the construction of novel and existing heterocycles is very important, ... See full document
303
Synthesis of nitrogen containing heterocycles via radical cyclisation
... as radical precursors had been reported by Newcomb'3’, while the use o f 0-benzoyl hydroxamic acid derivatives had been explored by ...amidyl radical generated from A-benzoyl protected hydroxamic acid ... See full document
278
Methyl (4 formyl 2 methoxycarbonylpyrrol 1 yl)acetate
... nitrogen heterocycles widely used in medicinal chemistry as well as the pharmaceutical and chemical industries and was selected for crystal structure determination in order to elucidate the conformation of ... See full document
7
Novel catalysts for the hydroxymethylation of allyl alcohol : a convenient synthetic route to 1, 4 butanediol
... Dynamic metal-ligand interactions offer one approach to supramolecular design, 2 and these binding motifs are principally represented by axial coordination of a nitrogen-donor to the metal centre of a ... See full document
190
Tetrahydroquinolines and Isoxazoles: Nitrogen heterocycles as potential antibacterial agents
... the heterocycles is found the antibacterial activity, which has had a growing interest because the inadequate use of antibiotic has increased the resistance of bacterial to the commercial antibiotics, even the ... See full document
6
The syntheses and testing of some nitrogen heterocycles for interaction with benzodiazepine receptors
... Thus, the use o f [3H]diazepam and an appropriate brain membrane preparation provides a simple and efficient in vitro binding assay to assess the affinity of compounds for benzodiazepine receptors. Accordingly this ... See full document
270
Facile synthesis of fused nitrogen containing heterocycles as anticancer agents
... One pot three components reaction of the pyrazol-5-one 1 with different aromatic aldehydes and malononitrile was carried out in the presence of Ammonium acetate to furnish the corresponding pyrazolopyridines 2a-g. ... See full document
18
Non bonding 1,5 S•••O interactions govern chemo and enantioselectivity in isothiourea catalyzed annulations of benzazoles
... To conclude, we have demonstrated the scope and limitations of the organocatalytic enantioselective functionalization of a range of benzazole nucleophiles using the isothiourea HyperBTM 1 and a,b-unsaturated ... See full document
9
An Efficient Synthesis of Ethyl {[3-(hydroxymethyl) quinolin-2-yl]thio}acetate
... sulfur–nitrogen heterocycles includes highly stable aromatic compounds, that display physicochemical properties with relevance in the design of new materials especially those relating to molecular ... See full document
5
Comparitive Study of Antiinflammataory, Analgesic and Antimicrobial Activity of Triazole Heterocycles Including Some Nitrogen Condensed and Bridged Heterocycles
... When the same type of triazoles was constructed from ibuprofen moiety substituted at 3 rd position having amino and mercapto groups at position 4 and 5 respectively furnished 3-[(4’-iso[r] ... See full document
6
The Synthesis and Biological Examination of 5-Membered Nitrogen-Based Heterocycles.
... Within the last two decades there has been a large amount of research devoted to Gram negative bacteria, identifying quorum sensing circuits for over 25 species of bacteria. W[r] ... See full document
262
A novel approach to steganone analogues via metal-mediated cyclisations
... a new product by thin layer chromatography, and after work-up, this material was isolated, although in trace amounts, as a colourless gum, along with a small amount of a colourless solid which proved to be the ... See full document
259
Synthesis of some benzothiazolyl and imidazole derivatives and evaluation of antibacterial activities
... In this investigation, benzothiazolyl and imidazole derivatives were prepared using a simple, general reaction scheme. By variation of alkyl and aromatic groups, a series of new compounds were prepared and ... See full document
8
2-Iodoisatogens: Versatile Intermediates for the Synthesis of Nitrogen Heterocycles
... Dipolar compounds represent an important class of intermediate in organic synthesis, largely because of their potential to undergo cycloaddition reactions towards complex functionalized [r] ... See full document
5
Application of one pot three component condensation reaction for the synthesis of new organophosphorus sulfur macrocycles
... 69.5 ppm), indicating the formation of a new product 13 rather than the expected 7. However, we are unable to separate the product 13, instead, an oxidised derivative 14 was isolated as a sole product (a pale- ... See full document
8
Related subjects