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[PDF] Top 20 New World Simian Foamy Virus Infections In Vivo and In Vitro

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New World Simian Foamy Virus Infections In Vivo and In Vitro

New World Simian Foamy Virus Infections In Vivo and In Vitro

... typical foamy virus replication, leading to CPE with formation of ...Old World SFV in human cells and suggests that the lack of New World SFV latent infection in hu- mans is not caused ... See full document

10

In Vivo Replication Capacity Rather Than In Vitro Macrophage Tropism Predicts Efficiency of Vaginal Transmission of Simian Immunodeficiency Virus or Simian/Human Immunodeficiency Virus in Rhesus Macaques

In Vivo Replication Capacity Rather Than In Vitro Macrophage Tropism Predicts Efficiency of Vaginal Transmission of Simian Immunodeficiency Virus or Simian/Human Immunodeficiency Virus in Rhesus Macaques

... in vitro replication kinetics of infec- tious virus stocks of SIVmac251, SIVmac239, SIVmac1A11, and SIVmac239/1A11/239 in rhesus macaque monocyte-de- rived ...in vivo replica- tion kinetics of the ... See full document

12

DNA binding properties of simian virus 40 T-antigens synthesized in vivo and in vitro.

DNA binding properties of simian virus 40 T-antigens synthesized in vivo and in vitro.

... Large T-antigen synthesized in cell-free protein-synthesizing systems primed by simian virus 40 mRNA also bound to DNA-cellulose, whereas small t- antigen similarly synthesized in vitro [r] ... See full document

8

Late replicative intermediates are accumulated during simian virus 40 DNA replication in vivo and in vitro.

Late replicative intermediates are accumulated during simian virus 40 DNA replication in vivo and in vitro.

... These intermediates sediment in neutral sucrose as a single peak of 29S and are seen when replicative intermediates are extracted from cells and ana- lyzed directly on alkaline gradients[r] ... See full document

10

Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitro.

Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitro.

... In these cultures, which were washed stringently each day to remove free virus and degenerating virus-infected cells, ap- proximately 1 in 100 cells inoculated with SIVmac239/17E-Br was [r] ... See full document

7

Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

... immunodeficiency virus inducing AIDS-like symptoms, and demonstrated that WR1065 inhibits SIV replication in TCBs activated from macaques infected for 14 months with ... See full document

10

Transcriptional complexity of vaccinia virus in vivo and in vitro.

Transcriptional complexity of vaccinia virus in vivo and in vitro.

... The results of DNA:RNA hybridization, using excess RNA derived from purified virion-associ- ated high-molecular-weight RNA, purified vir- ion-released 8 to 12S RNA, and total RNA syn- th[r] ... See full document

8

In Vivo Cellular Tropism of Gorilla Simian Foamy Virus in Blood of Infected Humans

In Vivo Cellular Tropism of Gorilla Simian Foamy Virus in Blood of Infected Humans

... Semiquantitative analysis of SFV DNA loads in the different PBMC populations of 2 individuals revealed that 10 4 to 10 5 CD8 T cells were sufficient to amplify SFV DNA, indicating a viral load of 1 to 10 SFV DNA ... See full document

7

Expanded Tissue Targets for Foamy Virus Replication with Simian Immunodeficiency Virus-Induced Immunosuppression

Expanded Tissue Targets for Foamy Virus Replication with Simian Immunodeficiency Virus-Induced Immunosuppression

... allowed foamy viruses to be particularly well adapted to their ...why foamy viruses are not pathogenic, while infection by their closest viral relatives, the complex retroviruses such as human ... See full document

8

Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus Infections

Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus Infections

... the virus can interact with macrophages and contribute to disease ...replication-competent virus can be retrieved from macro- phages, whether this virus is genetically disparate from virus re- ... See full document

11

Simian immunodeficiency virus infection of CD8+ lymphocytes in vivo.

Simian immunodeficiency virus infection of CD8+ lymphocytes in vivo.

... In addition, we observed no changes in percentage or expres- sion intensity of the CD4 1 CD8 1 population associated with SIV infection. SIV-infected CD8 1 cells have previously been described from in vitro ... See full document

5

Persistent Zoonotic Infection of a Human with Simian Foamy Virus in the Absence of an Intact orf-2Accessory Gene

Persistent Zoonotic Infection of a Human with Simian Foamy Virus in the Absence of an Intact orf-2Accessory Gene

... The SFV-3 orf-1 transactivator mediates viral transcription through response elements located within the internal pro- moter and U3 region of the LTR (31). The LTRs of FV tend to be large, ranging in length from 1,600 to ... See full document

6

Common Themes of Antibody Maturation to Simian Immunodeficiency Virus, Simian-Human Immunodeficiency Virus, and Human Immunodeficiency Virus Type 1 Infections

Common Themes of Antibody Maturation to Simian Immunodeficiency Virus, Simian-Human Immunodeficiency Virus, and Human Immunodeficiency Virus Type 1 Infections

... of virus-specific antibodies to SIV envelope antigens, this study revealed for the first time similar patterns of evolution of envelope-specific antibodies in response to SHIV infection during the first several ... See full document

8

Foamy virus zoonotic infections

Foamy virus zoonotic infections

... Old World monkeys and apes, SFV is rather eas- ily zoonotically transmitted and infected humans do not appear to have any pathology associated with SFV infec- ...offer new insights into anti-retroviral ... See full document

14

Wide distribution and ancient evolutionary history of simian foamy viruses in New World primates

Wide distribution and ancient evolutionary history of simian foamy viruses in New World primates

... The timescale is in millions of years. See Additional file 2: Table S1 for a complete list of species codes used in the study; PFV is primate foamy virus which is the new name given to HFV (human ... See full document

19

Novel simian foamy virus infections from multiple monkey species in women from the Democratic Republic of Congo

Novel simian foamy virus infections from multiple monkey species in women from the Democratic Republic of Congo

... Conclusions We report the results of a thorough epidemiologic inves- tigation of SFV infection in DRC. Using a combined serologic and molecular approach we identify human in- fection with new SFVs from Angolan ... See full document

15

An expanded search for simian foamy viruses (SFV) in Brazilian New World primates identifies novel SFV lineages and host age related infections

An expanded search for simian foamy viruses (SFV) in Brazilian New World primates identifies novel SFV lineages and host age related infections

... Conclusions Using very sensitive serological and molecular tools we expanded significantly the distribution of SFV in NWP in Brazil, including identification of infection in Leontopithecus, Chiropotes and Cacajao. We ... See full document

17

Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptases

Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptases

... Size exclusion chromatography and PR activity assays revealed a new feature special to spumaretrovirinae. FVs appear to express a monomeric PR domain within the Pol polyprotein which is catalytically inactive. In ... See full document

10

Frequent Simian Foamy Virus Infection in Persons Occupationally Exposed to Nonhuman Primates

Frequent Simian Foamy Virus Infection in Persons Occupationally Exposed to Nonhuman Primates

... SIV infections that adapted and was transmitted secondarily to become endemic in humans raises concerns about the introduction of a multitude of other simian retroviruses to ...10 new SFV-infected ... See full document

10

Horizontal acquisition and a broad biodistribution typify simian foamy virus infection in a cohort of Macaca fascicularis

Horizontal acquisition and a broad biodistribution typify simian foamy virus infection in a cohort of Macaca fascicularis

... One study in a wild Western chimpanzee population, with follow-up investigations in a sub-set of the animals, demonstrated a high degree of vertical SFV transmission and suggests this accounts for many primary ... See full document

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