[PDF] Top 20 Nonsteroidal anti inflammatory drugs (NSAIDs), cyxlooxygenase 2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice
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Nonsteroidal anti inflammatory drugs (NSAIDs), cyxlooxygenase 2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice
... using NSAIDs [36-46] (Table ...with gastrointestinal risk factors (including age ≥ 65 years) were not receiving appropriate ...one gastrointestinal risk factor was about 73% to 90% in the USA ... See full document
13
Faecal blood loss with aspirin, nonsteroidal anti inflammatory drugs and cyclo oxygenase 2 selective inhibitors: systematic review of randomized trials using autologous chromium labelled erythrocytes
... of gastrointestinal disease or surgery; oral, nasal, or rectal bleeding (including bleeding gums on brushing them); or ...all trials excluded current or recent use of drugs that are likely to ... See full document
9
Nonsteroidal anti inflammatory drugs and upper and lower gastrointestinal mucosal damage
... COX-2 selective inhibitors because post- hoc analyses of the Vioxx Gastrointestinal Outcomes Research (VIGOR) and MEDAL trials have reported diff erent ...to review the actual ... See full document
8
Nonsteroidal anti-inflammatory drugs in chronic pain: implications of new data for clinical practice
... (ns) nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for chronic pain ...adverse gastrointestinal (GI) and cardiovascular (CV) events among different ...controlled ... See full document
12
Cyclo oxygenase 2 selective inhibitors and nonsteroidal anti inflammatory drugs: balancing gastrointestinal and cardiovascular risk
... domised trials for celecoxib [19], lumiracoxib [20], rofecoxib [32], and valdecoxib [33], and for etoricoxib we combined a large randomised trial [23] with data from a meta-analysis of previous trials ... See full document
11
Cost-effectiveness analysis for joint pain treatment in patients with osteoarthritis treated at the Instituto Mexicano del Seguro Social (IMSS): Comparison of nonsteroidal anti-inflammatory drugs (NSAIDs) vs. cyclooxygenase-2 selective inhibitors
... systematic review was through electronic databases: Ovid-Medline, Elsevier-Science Direct, Proquest, Ebsco-E- Journal Services and ..."randomized clinical trial", "arthrosis", ... See full document
13
Discontinuation rates in clinical trials in musculoskeletal pain: meta analysis from etoricoxib clinical trial reports
... from clinical trial reports, which are more detailed in their reporting of the trials than are pub- lished papers, if only because they are not constrained by dic- tates of ... See full document
11
The role of medications and their management in acute kidney injury
... failure. Drugs are often implicated or contribute to the development of AKI, whether by affecting hemodynamics or by direct and indirect ...identifying drugs most com- monly associated with AKI can minimize ... See full document
9
Association of nonsteroidal anti-inflammatory drugs and aspirin use and the risk of head and neck cancers: a meta-analysis of observational studies
... randomized clinical trials due to the large sample size required; Second, we did not take into account possible interactions with other drugs due to absence of ...of NSAIDs are often ... See full document
12
The Role of Celecoxib as a Cox-2 Inhibitor Increasing the Radiosensitivity of Tumor Tissue
... in clinical response to treatment, resulting in a radiation dose reduction with acceptable and good clinical and pathological ...and clinical results in Tables 1 and 2. Above of this ... See full document
17
Results of a feasibility randomized controlled trial (RCT) of the Toolkit for Optimal Recovery (TOR): a live video program to prevent chronic pain in at-risk adults with orthopedic injuries
... ethnic sample from more ethnically diverse regions is warranted in future research. The research methodology and questionnaires were acceptable to study participants. Satisfaction with the TOR was high. There were no ... See full document
11
Global dimensions of chronic kidney disease of unknown etiology (CKDu): a modern era environmental and/or occupational nephropathy?
... However, as shown in the table, a number of similar- ities are present. The disease is characterized by substan- tial morbidity and mortality, resulting in death in young and middle aged adult patients, and absence of ... See full document
8
Effects of Eugenol On Acute Corneal Pain of Male Rats
... Most corneal pain sensory fibers are poly-modal activated by mechanical, thermal, and chemical stimulators [2]. Corneal pain is transferred by primary afferent fibers to the posterior horn of the medulla ... See full document
5
Assessing and treating primary headaches and cranio-facial pain in patients undergoing rehabilitation for neurological diseases
... During the last two decades, new clinical interventions, i.e. Mindfulness Therapy (Mind-T) and Acceptance and Commitment Therapy (ACT) (third-generation behav- ioural therapy), have been developed. Mind-T based ... See full document
18
Spinal radiographic progression over 2 years in ankylosing spondylitis patients treated with secukinumab: a historical cohort comparison
... to 2 years of ...< 2) at 4 years ...between anti-TNF agents and IL-17 blocking agents has been performed so far it can be expected that SURPASS (NCT03259074), an ongoing head-to-head study powered ... See full document
8
New horizons and perspectives in the treatment of osteoarthritis
... develop drugs that have the efficacy of NSAIDs but with an improved safety ...donating drugs (CINODs) may offer one alternative, and the potential ability of CINODs to ameliorate gastric damage due ... See full document
7
Health Related Quality of Life among Osteoarthritis Patients: A Comparison of Traditional Non Steroidal Anti Inflammatory Drugs and Selective COX 2 Inhibitors in the United Arab Emirates Using the SF 36
... and anti-inflammatory medications for pain management may improve symptoms but on long term may affect HRQoL ...non-steroidal anti-inflammatory drugs (NSAIDs) and ... See full document
9
Naproxen-Associated Renal Failure in a Child With Arthritis and Inflammatory Bowel Disease
... interstitial disease induced by nonsteroidal anti- inflammatory drugs differs from nonsteroidal anti- inflammatory drug-induced acute renal failure sec-. ondary to a reduction in glomeru[r] ... See full document
7
Lung-thorax compliance measured during a spontaneous breathing trial is a good index of extubation failure in the surgical intensive care unit: a retrospective cohort study
... According to Sandy et al., no difference was observed in the rate of extubation failure, duration of mechanical venti- lation, or ICU and hospital stays among the SBT using PAV, T-tube, and PSV [50]. Bosma et al. ... See full document
9
Risk of stroke associated with nonsteroidal anti-inflammatory drugs
... prospective trials suggested an asso- ciation with coronary ischemic events, the evidence for a link between NSAIDs and stroke events remains a source of ...of NSAIDs with respect to stroke ...if ... See full document
8
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