18 results with keyword: 'notch signaling during human t cell development'
Interestingly, following this strong Notch signal that induces the T- cell specifying transcriptional program (Taghon et al., 2005; Weerkamp et al., 2006a; Van de Walle et
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Rouge Entrée pour allumage par contact sec externe Vert Entrée pour allumage par contact sec externe Blanc Sortie contact sec (Follow).. Noir Sortie contact sec
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Hrb is regulated by Notch signaling in human T-ALL cell lines and is required for leukemia cell proliferation and survival
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Unlike previous work showing that hyper- activation of the Notch pathway in T lineage progenitors yields aggressive T cell acute lymphoblastic leukemia, these mice go on to develop
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essential regulators of hematopoietic stem cell development downstream of Notch signaling. Notch1 inhibits
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Clinical Implications: The Notch signaling pathway in T cells is critical for development of house-dust mite driven allergic airway inflammation in mice, indicating it could be
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Inhibition of Notch signaling increases neuron number during larval dorsal root ganglia development.. Genetic disruption of Notch signaling results in loss of neural crest induction
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Collectively, these data demonstrate that NOTCH signaling is dispensable in the differentiated cell lineages of osteoblasts or chondrocytes during fracture repair, while
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RLN and RXFP1 signals are localized predominantly in the cytotrophoblast (open arrows in A and B); strong signals for RXFP2 mRNA are localized in the maternal decidual cells
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Keywords: Notch-1, Notch-3, developmental signaling pathways, Notch inhibitors, NSCLC progenitor cells, CBF-1, MamL.. Progenitor cells in NSCLC and embryonic development
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y Greater than 0.3 ppm—could cause toxicity in sensi- tive plants, especially at low substrate pH; high Zn in Kentucky water sources is rare and could be a sign that the
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To determine the exact role and mode of action for the Notch pathway in MPCs we analyzed tissue-specific loss-of-function ( Prx1Cre; Rbpjk f/f ), gain-of-function ( Prx1Cre;
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Particularly, of the 137 annotated genes associ- ated with the NOTCH signaling pathway (GO:0007219, GeneWeaver), which is essential for inducing T-cell com- mitment and development,
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A short review of the distribu- tion of short-beaked common dolphins ( Delphinus delphis ) in the central and eastern North Atlantic with an abundance estimate for part of this
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In addition to Notch signalling, both TCF1 and GATA3 are required during early T cell development and gene expression analysis in ex vivo isolated T-cell precursors shows a
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