[PDF] Top 20 A NOVEL AND EXPEDIENT SYNTHESIS OF 1, 3 DIALKYL 6 METHYLPYRIMIDINEDIONES
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A NOVEL AND EXPEDIENT SYNTHESIS OF 1, 3 DIALKYL 6 METHYLPYRIMIDINEDIONES
... Although most of the above methodologies have their own synthetic values, some limitations mainly due to the use of dimethyl formamide as solvent with cumbersome workup of the reaction mixture, the long reaction times, ... See full document
9
Expedient synthesis of an atypical oxazolidinone compound library
... which novel libraries of compounds could be synthesised, by further derivatisation of the piperidine ring nitrogen. Incorporation of nitrogen atoms as the handle for diversification is desired as this potentially ... See full document
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ENVIRONMENTALLY BENIGN AND EXPEDIENT SYNTHESIS OF 1, 2 DIALKYLPYRIDAZINE 3, 6 DIONE DERIVATIVES
... hydrazine. 1-Phenyl-1, 2- dihydropyridazine-3, 6-dione have been synthesized by boiling a mixture of maleic anhydride and phenylhydrazine in glacialacetic acid 13 ...the synthesis of ... See full document
10
Synthesis and Crystal Structure Determination of 4’,9’,4”,9” Tetra t Butyl 1’,6’,1”,6” Tetramethoxy 2,5 Dithia[3 3] Metabiphenylophane
... The title large-sized metacyclophane compound 4’,9’,4”,9”-tetra-tert-butyl-1’,6’,1”,6”-tetramethoxy-2,5-dithia [3.3]metabiphenylophane as a cyclic ester consisting of two biphenyl parts and ... See full document
7
SYNTHESIS OF 2, 6 DIAMINO 3 PHENYLAZOPYRIDINE 1 OXIDE AND ITS HYDRO CHLORIDE
... 2, 6 –diamino -3-phenylazopyridine-N-Oxide hydrochloride 1: This Compound was prepared by two different routes starting from either 2,6- diamino-3-phenylazopyridine-1-oxide 5 or 2,6- ... See full document
5
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 1, 3, 4-THIADIAZOLE DERIVATIVES
... A.S. Synthesis of 1,3,4- thiadiazoles, imidazo[2,1-b]1,3,4-thiadiazoles and thiadiazolo[3,2-a]pyrimidines derived from benzimidazole as potential antimicrobial ... See full document
6
Design, synthesis and antibacterial activity of novel 1, 3 thiazolidine purine nucleosides
... With the advent of new modified nucleosides, scientists from all over the world have invested tremendous efforts towards the synthesis of purine libraries which will serve as a pathway for both drug leads and ... See full document
11
A NOVEL FUSED PYRIDOPYRIMIDINE DERIVATIVES: SYNTHESIS AND CHARACTERIZATION
... Egypt. 1 H-NMR spectrum was determined on a Jeol- Ex-500 NMR spectrometer and chemical shifts were expressed as part per million; (δ values, ppm) against TMS as internal reference, National Research Center, Cairo, ... See full document
6
Synthesis, Characterization and Anti Mycobacterial Activity of Novel Hydrazones
... poses 1, 2, 6, 7, 8 and 9 had one hydrogen bond between the receptor, Enoyl-[acyl-carrier-protein]reductase [NADH] and ligand ...pose 3 and 4 had 2 and four hydrogen bonds between the receptor and ... See full document
11
Synthesis and pharmacological screening of novel 6-methyl-2-oxo-4-substituted-5-(5-phenyl-1, 3, 4-oxadiazole-2yl)-1, 2, 3, 4-tetrahydropyrimidine
... To a hot solution (0.01mole) of compound 1 in ethanol (150 ml), was added hydrazine hydrate (99%, 0.015mole) and the reaction mixture was heated under reflux for 3 hrs. The solvent was removed to possible ... See full document
6
A Novel Synthesis of [4-(3-Methyl-1H-Indol-2-Yl)Phenyl]Phenylmethanone
... data were recorded with a Bruker 500 MHz high resolution NMR Spectrophotometer and CDCl 3 was used as a solvent. Chemical shifts are reported in ppm and tetramethylsilane was taken as internal standard. Mass ... See full document
7
The Dynamic Systems Adaptive Identification Algorithms on the Basis of the Regularity Principle
... n 0 , 1 ,..., . Under certain conditions parameters of object and the actuation device can be calculated independently [4]. These conditions are easily feasible at the solution of problems of identification and ... See full document
5
<p>Synthesis and characterization of a novel peptide-grafted Cs and evaluation of its nanoparticles for the oral delivery of insulin, in vitro, and in vivo study</p>
... Oral administration of drug-loaded NPs to investigate its efficacy on blood glucose level in diabetic animals Diabetic animals were divided (randomly) into groups of six animals each. In all the experiments including the ... See full document
12
Synthesis and characterization of a novel peptide-grafted Cs and evaluation of its nanoparticles for the oral delivery of insulin, in vitro, and in vivo study
... for 3 days in dialysis bags with MW cutoff point of 12,000 Da and ...Figure 1 shows the structure of Cs, the novel derivative of Cs, and the chemical conjugation ... See full document
12
Synthesis, Biological Evaluation and Molecular Docking Studies of Novel 1,8-Naphthyridine-3-carboxylic Acid Derivatives as Potential Antimicrobial Agents (Part-1)
... synthesized compounds have the potential of binding with one or the other amino acids in the active pocket as evident from the docking scores provided in (Table 7). The docked ligands were found to have similar binding ... See full document
13
Ditolyldithiophosphates of Gadolinium(III): Synthesis and Spectroscopic Characterization.
... cm 3 ) of gadolinium trichloride hexahydrate ...cm 3 ) of sodium O,O′-o-ditolyldithiophosphate ...[{(o-CH 3 C 6 H 4 O) 2 PS 2 } 3 Gd] (1) was obtained as ... See full document
5
Synthesis and Trypanocidal Evaluation of Some Novel 2 (Substituted Benzylidene) 5, 7 Dibromo 6 Hydroxy 1 Benzofuran 3(2H) Ones
... Substituted 2-benzylidene-1-benzofuran-3-ones are com- monly known as aurones that belongs to the naturally occurring flavonoids [1,2] and are structurally isomeric to flavones. They play significant role ... See full document
7
Synthesis and antimicrobial activity evaluation of new dialkyl heteroarylphosphonates
... Minimum inhibitory concentration [MIC] was determined for the title compounds. The lowest concentration of antimicrobial compounds that inhibit the visible growth of an organism after overnight incubation period is ... See full document
8
A Novel Synthesis of Oxazolidinone Derivatives (A Key Intermediate of Linezolid)
... were recorded using a 300-MHz Bruker Avance spectrometer. Chemical shifts values are expressed in δ (ppm) using TMS as the internal standard. The liquid chromatography-mass spectrometry (LC-MS) was performed on a 2010 EV ... See full document
5
SYNTHESIS OF NOVEL STEROIDAL 1, 2 DISUBSTITUTED PYRIDAZINE 3, 6 DIONES: A NEW ENTRY TO NITROGEN HETEROCYCLES
... their synthesis by simple and eco-friendly ...the synthesis of 1, 2-disterylpyridazine-3, 6-dione derivatives in two steps through double Chapman rearrangement under microwave ... See full document
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