[PDF] Top 20 Original Article Cost-effective use of aprepitant in multiple-day chemotherapy regimens
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Original Article Cost-effective use of aprepitant in multiple-day chemotherapy regimens
... of aprepitant (125 mg, day 1, 80 mg, days 2-5) to the standard antiemetic medication, including palonosetron ...mg, day 1) and dexamethasone (9.9 mg, day 1, ...The use of palo- ... See full document
11
Original Article Addition of aprepitant prevents chemotherapy-induced vomiting and nausea moderately when 5-Hydroxytryptamine-3 receptor antagonists and dexamethasone failed
... Abstract: Aprepitant is one of the effective antiemetic drugs that usually used for prevention of Capecitabine and oxaliplatin (XELOX) chemotherapy-induced nausea and vomiting ...XELOX ... See full document
6
Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting
... the cost effectiveness of aprepitant is limited to two ...with aprepitant plus standard therapy, or aprepitant added to a standard therapy only after CINV occurs (Moore et ...resource ... See full document
16
<p>Comparison of Pharmacokinetics of Aprepitant in Healthy Chinese and Caucasian Subjects</p>
... Among the 24 subjects in this study, 12 subjects experi- enced 18 mild or moderate AEs. All these AEs were transient in nature, and no subject withdrew because of an AE; no serious AEs occurred in this study. All AEs ... See full document
8
Original Article Efficacy of different regimens for treatment of idiopathic membranous nephropathy
... both regimens were proved to be effective on IMN, but the cyclophosphamide group had slighter adverse effects compared with the ch- lorambucil group ... See full document
10
Original Article Outcomes of combined chemotherapy, extensive
... In China, LSS has only recently been employed as a routine measure for treatment of primary malignant or symptomatic bone tumours, with wide implementation and success rates of these procedures lagging somewhat behind ... See full document
10
Controlling Chemotherapy Induced Nausea and Vomiting with Neurokinin 1 Receptor Antagonists in Patients on AC Based Chemotherapy—Are We There Yet?
... the use of aprepitant (APR) and casopitant (CAS) in breast cancer patients receiving AC-type (doxorubicin and cyclophosphamide) ...antiemetic regimens; as well as chemotherapy-related ... See full document
13
Original Article Effective use of PI3K inhibitor BKM120 to treat human osteosarcoma
... was effective in inhibiting OS cell proliferation, inducing cell cycle arrest and inducing cell apoptosis in ...an effective way to suppress tumor growth in ... See full document
9
Original Article Immunomodulatory effect of DC/CIK combined with chemotherapy in multiple myeloma and the clinical efficacy
... (Treg). Fifty MM patients were randomly divided into two groups: 24 cases in the simple chemotherapy group and 26 cases in the combined therapy group (chemotherapy plus DC/CIK immunotherapy). The ... See full document
10
Original Article Efficacy of neoadjuvant chemotherapy in breast cancer: arterial infusion chemotherapy vs intravenous chemotherapy
... (second chemotherapy), increasing the therapeutic efficacy ...infusion chemotherapy, and the chemotherapeutics are infused mainly via the internal mammary artery, lateral tho- racic artery and subclavian ... See full document
7
<p>Cost-Effectiveness Analysis of Tisagenlecleucel in the Treatment of Relapsed or Refractory B-Cell Acute Lymphoblastic Leukaemia in Children and Young Adults in Spain</p>
... During the fi rst 5 years, LYGs were estimated using parametric curves obtained from the OS results observed in the clinical studies (tisagenlecleucel: ELIANA, ENSIGN and B2101J; salvage chemotherapy: Von ... See full document
12
Comparative effectiveness of different chemotherapy regimens of advanced-stage Hodgkin lymphoma in adults: a network meta-analysis
... Results: Overall, we screened 3,564 citations and deemed 18 reports of 16 trials eligible and included them in our network meta-analysis. A total of 11,928 participants were randomly assigned to one of the 12 ... See full document
12
Use of locally available jaggery for development of a cost effective media for mass cultivation of piriformospora indica A step forward towards commercialization
... readily available synthetic media are expensive, there is a need to find an alternative medium for mass production of P. indica. The need arises as a cheaper and cost effective medium will bring down the ... See full document
5
Effective use of everolimus as salvage chemotherapy for ovarian clear cell carcinoma: a case report
... on day 1, every 21 days) and achieved ...this chemotherapy, however, the CA125 level increased and ascites developed, while computed tomography (CT) showed dissemination throughout the abdominal ... See full document
5
The use of perioperative chemotherapy in patients undergoing radical cystectomy for bladder cancer in Quebec (Canada), 2000 2016
... In a multivariable analysis (Table 2), year of surgery, age, Charlson’s comorbidity index, distance between the residence and hospital, hospital size, and hospital’s and surgeon’s radical cystectomy volume were ... See full document
23
Original Article Clinical use of Carica papaya leaf extract in chemotherapy induced thrombocytopaenia
... of chemotherapy induced thrombocyto- paenia has been recombinant interleukin-11 (rhIL-11) ...for cost effective anti-thrombocytopaenic agent is a time de- manding ... See full document
5
First-line chemotherapy regimens for locally advanced and metastatic pancreatic adenocarcinoma: a Bayesian analysis
... 63 regimens considered, 7 chemotherapy regimens that may achieve better overall survival than gemcitabine monotherapy for locally advanced and metastatic pancreatic cancer patients, with NSC-631570 ... See full document
14
Cost-Effectiveness of Docetaxel and Paclitaxel for Adjuvant Treatment of Early Breast Cancer: Adaptation of a Model-Based Economic Evaluation From the United Kingdom to South Africa
... more effective. The estimated difference in mean cost per patient was R578 and R1512, generating ...of cost-effectiveness is ...of cost-effectiveness increases to ...the ... See full document
11
Cost utility analysis of palonosetron in the antiemetic regimen for cisplatin containing highly emetogenic chemotherapy in Japan
... incremental cost was 10, 455 JPY ...acceptable cost per QALY ratios in Japan’s health ...not cost- effective for HEC in ...considered cost-effective by commonly applied ... See full document
10
Original Article Bortezomib-based chemotherapy regimens can improve response in newly diagnosed multiple myeloma patients with bcl-2 and survivin overexpression
... diagnosed multiple myeloma ...Bortezomib-based regimens were more effective in reducing tumor burden and achieving therapeutic (complete and partial) response compared with non-bortezomib-based ... See full document
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