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[PDF] Top 20 Original Article Elevated plasma levels of IL-12 and IFN-γ in systemic lupus erythematosus

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Original Article Elevated plasma levels of IL-12 and IFN-γ in systemic lupus erythematosus

Original Article Elevated plasma levels of IL-12 and IFN-γ in systemic lupus erythematosus

... with IL-12 and IFN-γ expressions. The AUCs of IL-12 and IFN-γ for predicting SLE were ...that IL-12 and IFN-γ can be consid- ered as two ... See full document

6

Original Article Association of single nucleotide polymorphisms and haplotypes of interleukin-10 5’flanking region with systemic lupus erythematosus susceptibility in Han Chinese

Original Article Association of single nucleotide polymorphisms and haplotypes of interleukin-10 5’flanking region with systemic lupus erythematosus susceptibility in Han Chinese

... 17]. IL-10, a 36 kD homodimer cytokine once defined as cytokine synthesis inhibitory factor (CSIF) can suppress the secretion of IL-1, tumor necrosis factor (TNF-α), IL-6, IL-8 and ... See full document

7

Original Article Changes in levels of IL-9, IL-17, IFN-γ, dendritic cell numbers and TLR expression in peripheral blood in asthmatic children with Mycoplasma pneumoniae infection

Original Article Changes in levels of IL-9, IL-17, IFN-γ, dendritic cell numbers and TLR expression in peripheral blood in asthmatic children with Mycoplasma pneumoniae infection

... the levels of cytokines related to airway inflam- mation will ...serum levels of sev- eral cytokines in pediatric asthma patients with upper or lower respiratory infection with ...included IL-1α and ... See full document

10

Original Article Docosahexaenoic acid suppresses pro-inflammatory macrophages and promotes anti-inflammatory/ regulatory macrophage polarization through regulation of cytokines

Original Article Docosahexaenoic acid suppresses pro-inflammatory macrophages and promotes anti-inflammatory/ regulatory macrophage polarization through regulation of cytokines

... (IFN-γ, IL-12, IL-4 and IL-10) was detected, with or without LPS chal- ...and levels of IFN-γ, IL-12, IL-4, and IL-10 were ... See full document

8

Original Article Expression level of plasma Bcl-xL and Bcl-2 in patients with systemic lupus erythematosus

Original Article Expression level of plasma Bcl-xL and Bcl-2 in patients with systemic lupus erythematosus

... a systemic autoim- mune disease resembling human ...in lupus- prone NZB/W F1 mice and human peripheral blood including SLE and con- trols in vitro, their results showed that ABT-199 treatment efficiently ... See full document

6

Original Article Protective effects of bifidobacterial adhesin on intestinal mucosa of stressed male rats via modulation of inflammation

Original Article Protective effects of bifidobacterial adhesin on intestinal mucosa of stressed male rats via modulation of inflammation

... group). Levels of NF-κB, IL-10, TNF-α, and IFN-γ were measured at different time points, in plasma and intestinal mucosa ...microscopy. Plasma and/or mucosal levels of ... See full document

8

Systemic lupus erythematosus and the type I interferon system

Systemic lupus erythematosus and the type I interferon system

... produce IFN- α . Fc γ RIIa is necessary for the activation of NIPCs/PDCs by ...mediating IFN- α synthesis induced by CpG-DNA, but the role of this receptor for the response to IICs is ...induces ... See full document

8

DNA damage levels in systemic lupus erythematosus patients with low disease activity: An evaluation by comet assay

DNA damage levels in systemic lupus erythematosus patients with low disease activity: An evaluation by comet assay

... Oxidative stress has been implicated in the inflam- matory process of Systemic Lupus Erythematosus (SLE), particularly by the formation of anti-DNA autoantibodies, which can lead to DNA damage. The ... See full document

6

Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus

Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus

... to ROC curve analyses (cross-sectional study 0.39 mg/L for higher disease activity and 0.42 mg/L for LN; longitudinal study 1.1 mg/L for LN). ROC curves and AUCs, together with positive predictive values (PPVs) and ... See full document

9

Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity

Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity

... enhances IL-6 pro- duction from human PBMCs in the presence of TLR9 signaling triggered by CpG, but does not enhance TLR3, 4, or 7 signaling (Figure ...produce IL-6, whereas neutraliza- tion of PGRN in ... See full document

9

The identification of a novel splicing mutation in C1qB in a Japanese family with C1q deficiency: a case report

The identification of a novel splicing mutation in C1qB in a Japanese family with C1q deficiency: a case report

... At present, no specific therapy is available for C1q deficiency, so steroids and immunosuppressive agents such as hydroxychloroquine (not currently available in Japan) are used as treatments. Bone marrow trans- ... See full document

6

Original Article Effect of rTsP53 on the M1/M2 activation of bone-marrow derived macrophage in vitro

Original Article Effect of rTsP53 on the M1/M2 activation of bone-marrow derived macrophage in vitro

... (IFN-γ, IL-6 and TNF-α) level decreased in the culture medium supernatant of BMDM co-incubated with ...and IL-13) and regulatory cyto- kines in the culture medium ...with IFN-γ, ... See full document

16

Secondary angle closure glaucoma by lupus choroidopathy as an initial presentation of systemic lupus erythematosus: a case report

Secondary angle closure glaucoma by lupus choroidopathy as an initial presentation of systemic lupus erythematosus: a case report

... One month after the first visit, her best corrected visual acuity was 20/32 in both eyes, with −2.75D for the right eye and −3.00D for the left eye. After medication, IOP was 17 mmHg in both eyes. FAG showed no leak- age ... See full document

7

Plasma levels of osteopontin identify patients at risk for organ damage in systemic lupus erythematosus

Plasma levels of osteopontin identify patients at risk for organ damage in systemic lupus erythematosus

... mean systemic lupus erythematosus disease activity index; anti-dsDNA: anti-double stranded DNA; aSLE: adult-onset systemic lupus erythematosus; AUC: area under the curve; C3: ... See full document

12

Original Article Pathologic diagnosis of spontaneous splenic rupture in systemic lupus erythematosus

Original Article Pathologic diagnosis of spontaneous splenic rupture in systemic lupus erythematosus

... Systemic lupus erythematosus (SLE) is a com- mon and suffering disease that involves multi- ple organs, and shortens life span [4]. Involvement of spleen with subsequent sponta- neous rupture is a ... See full document

8

A promising approach to targeting type 1 IFN in systemic lupus erythematosus

A promising approach to targeting type 1 IFN in systemic lupus erythematosus

... understanding systemic lupus erythematosus (SLE) pathogenesis, most clinical trials of new targeted therapies have been met with ...I IFN pathway is believed to play an important role in SLE, ... See full document

5

SYSTEMIC LUPUS ERYTHEMATOSUS AND SYNDROMES POSSIBLY RELATED

SYSTEMIC LUPUS ERYTHEMATOSUS AND SYNDROMES POSSIBLY RELATED

... SYSTEMIC LUPUS ERYTHEMATOSUS AND SYNDROMES.. POSSIBLY RELATED![r] ... See full document

17

Successful use of Ustekinumab in a Patient with Psoriasis,
Psoriatic Arthritis and Systemic Lupus Erythematosus: A Case
report and Review of literature

Successful use of Ustekinumab in a Patient with Psoriasis, Psoriatic Arthritis and Systemic Lupus Erythematosus: A Case report and Review of literature

... of systemic and cutaneous lupus included “SLE”, “systemic lupus erythematosus”, “discoid lupus”, “acute cutaneous lupus erythematosus”, “subacute cutaneous ... See full document

5

Original Article The effect of prednisone acetate combined with cyclophosphamide on systemic lupus erythematosus and serum IL-4, IL-6, and IL-10 expressions

Original Article The effect of prednisone acetate combined with cyclophosphamide on systemic lupus erythematosus and serum IL-4, IL-6, and IL-10 expressions

... However, there are still some limitations in this study. Firstly, this clinical trial did not clarify the mechanism of prednisone acetate combined with cyclophosphamide affecting the expres- sions of IL-4, ... See full document

8

Circulating exosomes from patients with systemic lupus erythematosus induce a proinflammatory immune response

Circulating exosomes from patients with systemic lupus erythematosus induce a proinflammatory immune response

... control; IFN: Interferon; IL: Interleukin; IQR: Interquartile range; miRNA: MicroRNA; PAMP: Pattern-associated molecular patterns; PBMC: Peripheral blood mononuclear cell; PBS: Phosphate-buffered saline; ... See full document

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