[PDF] Top 20 Original Article Expression of guanylyl cyclase C and its prognostic value in different developing stages of colorectal cancer patients

... clarify its contribu- tion to OS and ...membranous expression was an inde- pendent hazard factor of both OS ...branous expression was negatively associated with improved ...stage colorectal ... See full document

... CRC patients and found to correctly discriminate CRC patients from healthy controls with an AUC value of ...CRC patients who received surgery ...miR-193b expression with clinico- ... See full document

... the expression of adhesion molecules, E-cadherin (ECAD), CD24, CD44 and osteopontin (OPN) in colorectal cancer (CRC) has been limited, even though CRC is one of the leading causes of ... See full document

... low expression in colorectal cancer ...the prognostic role of CDX2 in colorectal cancer remains ...2547 patients was conducted to evaluate the prognostic ... See full document

... investigated different integrins (α v β 3 , α v β 5 , α v β 1 , α v β 6 , α v β 8 , α 2 ) in CRC and its metastases, showing that blockade of them in cell lines of primary or metastatic can- cer caused a ... See full document

... breast cancer tissues was correlat- ed with larger tumor size and advanced clinical ...suppressed cancer cell growth, prolifera- tion and colony formation in vitro by targeting cyclinD2 ...gastric ... See full document

... of colorectal cancer (CRC) is still not ...examined expression of hsa_circ_0007534 in plasma to verify whether it can be utilized to diagnose and monitor CRC in routine clinical ...CRC ... See full document

... (67.8%) patients had tumors located in the colon, and 63 ...(40%) patients had positive lymph nodes, and 40 (20.5%) patients had distant metasta- ...CRC patients was performed according to the ... See full document

... CRC cancer. Acc- ordingly, this protein could serve as prognostic biomarkers and therapeutic targets for treating patients with surgically resectable ...potential prognostic mark- ers for ... See full document

... aberrant expression of urothelial carcinoma-associated 1 (UCA1) was reported in gastric cancer, esophageal squamous cell carcinoma, melanoma, breast cancer, tongue squamous cell carcinomas, as well ... See full document

... a prognostic marker is simple and feasible in routine ...identifying patients at high risk of tumor ...of different immunoscore in tumor ...to patients with CRC immunoscore as a poor ... See full document

... membrane-bound guanylyl cyclases, is a homodimeric transmembrane enzyme exhibiting conserved functional domains (Figure 3A), including: (1) the extracellular domain for specific ligand binding; (2) a single ... See full document

... endometrial cancer (EC) and the antago- nistic functional effects of Tra2β on alternative splicing correlate directly to their opposite clini- cal effects on EC patient outcome ...ovarian cancer leading to ... See full document

... for its homologs because it displays a high catalytic activity ...and its association with breast cancer treatment and prognosis, transcriptional regu- lation of HER2 expression is not well ... See full document

... the original ALI and inferred that the original ALI was a simple but strong prognostic indicator of clinical ...excellent prognostic value for ALI in radically treated LAPC ... See full document

... 90 patients with colorectal cancer, which was obtained from tissue specimen bank within Shanghai biological technology ...83 patients were followed-up until August 2014. All the ... See full document

... 88 patients with colorectal carcinoma who underwent pulmonary metastases resection were retrospectively reviewed and ...and expression of p53 were retrospectively ...The prognostic effect of ... See full document

... of patients who were lost to follow-up or died from diseases other than CRC were considered censored data in the survival ...the patients, and the study was approved by the Ethics Committee of Jinling ... See full document

... GC-C gene targeting. The gene encoding GC-C was disrupted by inserting a neomycin resistance gene cassette, in the oppo- site transcriptional orientation, in exon 1 (Fig. 1). Transcrip- tion of the targeted ... See full document

... these patients received adjuvant therapy be- fore the ...202 patients was collected, such as age, gender, BMI, ASA levels, cancer location, pathology, blood markers, surgery procedures, ... See full document