[PDF] Top 20 Original Article Lower miR-145-5p expression and its potential pathways in hepatocellular carcinoma: a bioinformatics analysis with RNA-seq and microarray data
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Original Article Lower miR-145-5p expression and its potential pathways in hepatocellular carcinoma: a bioinformatics analysis with RNA-seq and microarray data
... meta- analysis displayed that miR-145-5p expressed markedly lower in HCC tissue than that in non- cancerous liver tissue ...subgroup analysis was conducted. Results showed that ... See full document
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Original Article Elevation of miR-191-5p level and its potential signaling pathways in hepatocellular carcinoma: a study validated by microarray and in-house qRT-PCR with 1,291 clinical samples
... The miR-191-5p expression has been reported to increase in hepatocellular carcinoma (HCC), but its clinical value and exact role remain to be further ...comprehensive ... See full document
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Original Article The clinicopathological significance of decreased miR-125b-5p in hepatocellular carcinoma: evidence based on RT-qPCR, microRNA-microarray, and microRNA-sequencing
... The expression levels of miR-125b-5p have been measured by several groups but with small sample sizes, and the results have been inconsistent ...of miR-125b-5p in HCC, has not been ... See full document
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Original Article Genetic alteration and prospective signaling pathways of miR-517a-3p in bladder cancer: a study based on miRNA sequencing data and bioinformatics methods
... cancers. MiR-517a-3p is one of the attention-grabbing cancer-relevant miRNAs which has been involved in different ...prominently lower expression of miR-517a-3p was detected in seminomas than ... See full document
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Original Article Clinical value and potential targets of miR-224-5p in hepatocellular carcinoma validated by a TCGA- and GEO- based study
... identified miR-224 upregulation in HCC was association with p65/ NFκB and inflammatory pathways [27], while Wang et al discovered the overexpression of miR-224 in HCC has connection with EP300 ...of ... See full document
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Original Article Potential targeting pathways of microRNA-376c in human cholangiocarcinoma: an analysis based on mRNA microarray and bioinformatics
... non-coding RNA, has been reported to play vital roles in various ...the potential targeting pathways of microRNA-376c in human cholangio- carcinoma based on data from an mRNA ... See full document
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Original Article Down-regulation of miR-26a-5p and its regulatory roles in hepatocellular carcinoma: an in silico analysis
... and microarray data respectively, practical studies comprising of RT-qPCR and fluorescence in situ hybridization (FISH) should be conducted to validate their ...current analysis, we discovered no ... See full document
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Original Article Overexpression of MiR-452-5p in hepatocellular carcinoma tissues and its prospective signaling pathways
... The expression lev- els of miR-452-5p in cancerous tissues were markedly up-regulated compared to the non- cancerous tissues in the 11 databases ...GSE data (GSE41874, GSE98269), no difference ... See full document
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Review Article Upregulated miR-18a-5p and its regulatory roles in hepatocellular carcinoma: a study based on bioinformatics analysis with miRNA-seq and miRNA-microarray data
... Background: Expression levels of miR-18a-5p and its molecular mechanisms in hepatocellular carcinoma (HCC) remain poorly ...examine expression profiling of ... See full document
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Original Article Prospective target genes and pathways of miR-30a-5p in colorectal cancer: an investigation using TCGA and bioinformatics analysis
... the potential mechanism of mircroRNA-30a-5p (miR-30a-5p) in colorectal cancer (CRC) development using The Cancer Genome Atlas (TCGA) and a bioinformatics ...The miR-30a-5p ... See full document
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Clinical significance of mitofusin 2 and its signaling pathways in hepatocellular carcinoma
... 18 pathways, including the PI3K–Akt signaling pathway, cyto- kine–cytokine receptor interaction, focal adhesion, and dir- ect p53 ...these pathways play important roles in tumor development and progression ... See full document
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Original Article Mechanism of ribavirin in treatment of hepatocellular carcinoma via microarray analysis
... a potential role in ...the potential prognosis of tumorigenic dis- ...way analysis, we uncovered the underlying mechanisms of ribavirin in the progression of ...lung carcinoma (SCLC) is a ... See full document
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Original Article Role of miR-1 and its potential regulation of signaling pathways in bladder cancer: a comprehensive investigation based on TCGA, GEO, ArrayExpress, and bioinformatics analysis
... as miR-1, miR-133a, miR-133b, and miR-206, are abnormally expre- ssed in certain malignancies and that they play vital roles in tumor initiation, progression, and ...of miR-1 in BC, ... See full document
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Lower expressed miR-198 and its potential targets in hepatocellular carcinoma: a clinicopathological and in silico study
... relevant lower expression of miR-198 in HCC, as compared to that in their para- noncancerous liver ...Downregulated miR-198 level was closely related to the disease progression of ...that ... See full document
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Original Article miR-181a-5p is downregulated and inhibits proliferation and the cell cycle in prostate cancer
... gene expression. Previous reports showed altered expression of miRNAs in numerous hu- man malignancies, including prostate cancer ...of miR- NAs in PCa could provide a novel insight to search the ... See full document
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Original Article Decreased expression of serum miR-424 correlates with poor prognosis of patients with hepatocellular carcinoma
... Although miR-424 has been demonstrated to inhibit progression of hepatocellular carcinoma (HCC), its expression level in serum samples and the potential clini- cal values remain ... See full document
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Original Article Identification of the clinical diagnostic value of miR-10b-5p and the key targets and pathways in glioma, a study based on meta-analysis and bioinformatics
... all, miR-10b-5p was overexpressed in glioma and may act as a satisfactory diagnos- tic ...of miR-10b-5p including PHLPP2, MAKP1, RPS6KA2, PRKCE, YWHAG, EPHA4, and NEDD4L, especially PRKCE and ... See full document
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Original Article MiR-26b inhibits hepatocellular carcinoma cell proliferation, migration, and invasion by targeting EphA2
... in expression of their target ...the expression of miR-16b in eight hepatocellular carcinoma (HCC) cell lines, revealed the roles of miR-26b on hepatocellular ... See full document
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miR-363-5p as potential prognostic marker for hepatocellular carcinoma indicated by weighted co-expression network analysis of miRNAs and mRNA
... and its protein are expressed in HCC, indicating that ZNF family may be involved in tumor biology of HCC ...between miR-363-5p and its target genes ... See full document
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Original Article Expression of HDAC4 in hepatocellular carcinoma and its correlation with prognosis
... of hepatocellular carcinoma cells and reduced the survival time of ...of hepatocellular carcinoma, HDAC4 might participate an unknown tumor suppress network and prolong the survival time of ... See full document
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