[PDF] Top 20 Original Article Expression of IL-4 and IL-13 predicts recurrence and survival in localized clear-cell renal cell carcinoma

... and IL-13 are anti-inflammatory and immunoregulatory cytokines that can influence cancer-directed ...tumor-derived IL-4 and IL-13 in patients with localized ccRCC after ... See full document

... better survival in bladder cancer, myxofibrosarcoma and gastro- intestinal cancer [11, 12], while CD44s overex- pression was associated with poor survival in pharyngeal and laryngeal cancer patients ...no ... See full document

... with localized or locally advanced ccRCC who presented at The First Affiliated Hospital and The Third Affiliated Hospital of Sun Yat-sen University between 2003 and ...The original inclu- sion criteria were ... See full document

... Seventy-four of 90 samples were involved in the analysis except for patients with metasta- sis (3 cases), loss of follow-ups (9 cases), and absence of information of TNM phase (4 cases). The clinical features of ... See full document

... ligand 4 (Dll4) and Notch signaling pathway plays a key role in embryonic vascular develop- ment and tumor ...the expression of Dll4 in clear cell renal cell carcinoma ... See full document

... Renal cell carcinoma (RCC) is the most preva- lent malignancy of the adult kidney, accounting for approximately 90-95% of all kidney neo- plasm ...and 4% annually) ...with recurrence ... See full document

... with renal cell carcinoma (RCC) each year, accounting for 2-3% of adult solid ...[1]. Clear cell renal cell carcinoma (ccRCC) accounts for approxi- mately 70% of ... See full document

... The expression status of WNT6 in ESCCs and their clinico-prognostic significanc- es remain to be ...WNT6 expression and survival parameters were ...long-term survival in ESCC ... See full document

... The light zone B cells known as centrocytes are derived from the dark zone centroblasts (MacLennan, 1994a). The hght zone cells are smaller and less closely packed and are separated by a dense network of FDCs. The hght ... See full document

... TaqMan Gene Expression Assays (Thermo Fisher Scientific, USA) were used to estimate the mRNA level of genes. The following kits were selected: RARA (Hs00940446_m1); RARB (Hs00977140_m1), RARG (Hs01559234_m1), RXRA ... See full document

... Although our study revealed the prognostic significance of Dot1l expression ccRCC patients, some limitations remain to be acknowledged. As this is a retrospective study and all samples and data of patients were ... See full document

... that expression of miRNAs is deregulated in various types of human cancer like renal cancer, pros- tate cancer, breast cancer, lung cancer and pancreas cancer ...human renal cancer, lots of miRNAs ... See full document

... necessary. Recurrence was defined as: imaging studies or biopsy confirmed new lesions in the liver or out- side the ...Free Survival (DFS) was defined as the time from the date of surgery to the time of ... See full document

... SPRY4-IT1 expression resulted in cell growth defects, decreased invasion and migration, and increased rates of apoptosis in melanoma cells ...the cell proliferation, migration and inva- sion in human ... See full document

... co expression of CAV1 and activated components of the AKT/mTOR pathway represents a ‘ linked molecular signature ’ that identifies patients with localized RCC that are at high risk of developing meta- ... See full document

... the renal capsule, involvement of adrenal gland, lymph nodal involvement and metastasis to distant organs, and all of which are established independent prognostic markers and when they are assessed in combination ... See full document

... Co‑expression network construction and module analysis Firstly, expression data profile of DEGs was tested by to check if they were the good samples and good genes. Afterwards, power value was screened out ... See full document

... 14 renal cell carcinomas and found the leiomyo- matous stromal component in all analyzable (8/14) cases to be polyclonal and therefore reactive rather than ...in renal cell carcinomas is poly- ... See full document

... reduced cell proliferation, migration and invasion ability in Caki- 1 cells, and that a mimic of miR-27a-3p significantly increased cell proliferation, migration and invasion abilities in 786-O ...cancer ... See full document

... PGAM1 expression was found in both normal kidney and CCRCC, but the high-expression rate of PGAM1 in CCRCC was significantly high- er compared with those in normal ...hepatocellular carcinoma, oral ... See full document