[PDF] Top 20 Original Article Gene expression profiling and identification of key genes involved in neonatal hypoxic-ischemic brain injury
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Original Article Gene expression profiling and identification of key genes involved in neonatal hypoxic-ischemic brain injury
... the Gene Expression Omnibus (GEO) database [19] in NCBI ...the original study [18], pregnant Wistar rats were purchased and the pups were reared with their dams until the start of the ...HI ... See full document
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Original Article The expression of PI3K/Akt signaling pathway and PTEN in hippocampus of the brain and the correlation with cognitive impairment after neonatal hypoxic ischemic brain damage in rats
... PTEN gene have been known to be closely related to hypoxia-ischemia brain injury, we hypothesized that they are involved in neonatal hypoxic ischemic brain damage ... See full document
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Original Article Hyperbaric oxygenation promotes neural stem cell proliferation and protects the learning and memory ability in neonatal hypoxic-ischemic brain damage
... was involved with the Nestin expression after ...Nestin expression was observed in astrocytes following brain inju- ry ...Nestin expression in astrocytes consisted with the embryonal ... See full document
8
Granulocyte Stimulating Factor Attenuates Hypoxic ischemic Brain Injury by Inhibiting Apoptosis in Neonatal Rats
... on neonatal hypoxic-ischemic brain ...after hypoxic-ischemic insult, hypoxia-ischemia induced increase in TUNEL-positive cells, annexinV+/PI- and JC-1 positive apoptotic cells in ... See full document
7
Use of estetrol with other steroids for attenuation of neonatal hypoxic-ischemic brain injury: to combine or not to combine?
... to injury. In the adult rat brain, the upregulation of nitric oxide synthase-2 (NOS-2), involved in production of nitric oxide free radicals, and pro-inflammatory IL-1β after ischemic events ... See full document
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Host parasite interaction: changes in human placental gene expression induced by Trypanosoma cruzi
... As expected, T. cruzi modifies an ample range of bio- logical processes during tissue invasion and infection. As described before, the parasite dramatically changes the gene expression in single cells [10]. ... See full document
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Inhibition of miRNA-210 reverses nicotine-induced brain hypoxic-ischemic injury in neonatal rats
... nicotine-treated neonatal brain was mixed with reverse-transcription master mix in a final volume of 20 µl and incubated for 60 min at 37 ℃, and the reaction was stopped at ...reference gene ... See full document
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Original Article Granulocyte-colony stimulating factor in combination with AMD3100 confers greater neuroprotection after hypoxic-ischemic brain damage than a solitary treatment in mice
... AMD3100 has been shown to result in a signifi- cant mobilization of progenitor cells via disrupt- ing SDF-1α/CXCR4 bond, the primary progeni- tor cell anchor in the bone marrow. Meanwhile, as a selective antagonist of ... See full document
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MR Imaging Quantification of Cerebellar Growth Following Hypoxic Ischemic Injury to the Neonatal Brain
... of injury include the cortex and subcortical white matter ...conventional neonatal MR im- ...cerebellar injury in infants with severe injury may not be obvious on early MR imaging (25), but in ... See full document
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Original Article Knockdown of NF-κB-inducing kinase prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns
... increased expression and nuclear transloca- tion of p52 through the non-canonical pathway and hence increased the transcriptional activi- ty of NF-κB [15, ...liver injury and fibrosis lead- ing to death in ... See full document
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Identification of key genes and specific pathways potentially involved in androgen-independent, mitoxantrone-resistant prostate cancer
... 636 genes were differentially expressed (P < ...downregulated genes according to the log ratio expres- sion values (Tables 1 and 2), and among these, the ones in the MTX-resistant CRPC groups whose ... See full document
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Original Article Effect of hyperbaric oxygen on neurological recovery of neonatal rats following hypoxic-ischemic brain damage and its underlying mechanism
... received hypoxic treatment (8% oxygen) at 37°C at a flow rate of ...the brain was collected. The macroscopic features of the brain were recorded and then the brain was placed in a freezing ... See full document
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<p>Identification of Key Genes Involved in Diabetic Peripheral Neuropathy Progression and Associated with Pancreatic Cancer</p>
... 729 genes (dark green dots) (FDR < 0.01). The 50 signi fi cant gene sets positively and negatively associated with MMP9 are shown in the heat map in Figure 5B and ...cant genes positively and ... See full document
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Original Article Identification of key genes and pathways in human glioblastoma multiforme by co-expression analysis
... 1, genes in the 3 clusters were mainly associated with cell cycle regulation, cell division, and immune response, highlighting their key roles in regulating GBM ...relevant expression pat- ...set. ... See full document
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Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic ischemic brain injury
... H-I injury and have some features in common with programmed cell death ...after brain injuries with prom- inent delayed cell death, then there may be a prolonged win- dow for therapeutic treatment with ... See full document
9
Resveratrol post-treatment protects against neonatal brain injury after hypoxia-ischemia
... ischemia/reperfusion injury [9, ...perinatal hypoxic-ischemic brain injury ...against neonatal hypoxic-ischemic brain ... See full document
15
Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury
... of neonatal HI, mitochondrial respiration and calcium homeostasis are impaired ...rodent neonatal HI models ...to neonatal HI insult [10] and a wide range of mitochondrial morphologies are observed ... See full document
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Intrapartum factors associated with neonatal hypoxic ischemic encephalopathy: a case controlled study
... Identifying risk factors for HIE are key, because if they develop intrapartum and are modifiable, specific inter- ventions or labor and delivery practices may impact the incidence of HIE. To date, studies to ... See full document
7
Neonatal dexamethasone treatment exacerbates hypoxic-ischemic brain injury
... HI-induced brain injury is one of major causes of ...the neonatal brain to subsequent HI ...protect neonatal brain against subsequent HI injury [15,16,34], our results do ... See full document
11
Original Article Bioinformatics analysis of gene expression profile data to screen key genes involved in cardiac ischemia-reperfusion injury
... essed genes were most significantly as- sociated with inflammation mediated by che- mokine and cytokine signaling pathway, ...I/R injury and inflammation after on-pump coronary artery bypass graft sur- ... See full document
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