[PDF] Top 20 Original Article Fibrosis and cardiac dysfunction in insulin-resistant rats: changes in myocardial type I collagen and telmisartan’s effects
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Original Article Fibrosis and cardiac dysfunction in insulin-resistant rats: changes in myocardial type I collagen and telmisartan’s effects
... Abstract: Myocardial fibrosis may be an important contributor to the association of insulin-resistance with cardiac ...the effects of telmisartan on cardiac function and ... See full document
10
Original Article Effects of low-frequency noise on cardiac collagen and cardiomyocyte ultrastructure: an immunohistochemical and electron microscopy study
... tissue fibrosis. We previously re- ported the development of myocardial and perivascular fibrosis and a reduction of cardiac connexin43 in rats, but data is lacking concerning the ... See full document
9
Original Article Association between collagen cross-linking and cardiac function and remodeling in rats with furazolidone-induced dilated cardiomyopathy
... of collagen mechanics [16]. Properties such as collagen fiber diameter and the ratio of collagen I to III all contribute to the mechanical behavior at the tissue level [17, ...Col I ... See full document
9
Original Article Anti-inflammatory effects of lycopene prevents cardiac dysfunction in streptozotocin-diabetic rats
... ous type of cells ...cause myocardial hypertrophy and fibrosis in diabetes ...of fibrosis in various tissues ...alleviates fibrosis in many diseases, such as hypertensive cardiac ... See full document
8
Original Article Qiliqiangxin ameliorates cardiac dysfunction in heart failure rats post myocardial infarction via activation of HIF/VEGF pathway
... Male Sprague-Dawley rats, weighing 200-250 g, were purchased from Experimental Animal Center of Shanghai Medical College, Fudan University. All animal experiments were per- formed in compliance with the Guide for ... See full document
9
Cardiac remodeling and myocardial dysfunction in obese spontaneously hypertensive rats
... SHR-ob, cardiac protein expression of GLUT1 was increased compared to SHR-lean and normotensive con- ...the insulin in- dependent glucose transporter GLUT1 is a major mediator of basal cardiac ... See full document
10
Gualou Xiebai decoction inhibits cardiac dysfunction and inflammation in cardiac fibrosis rats
... To determine the heart hemodynamic function, parame- ters were measured in closed-chest anesthetized rats [11]. Animals were anesthetized with chloral hydrate and trachea was intubated to facilitate breathing. ... See full document
8
Original Article The protective effect of trimetazidine on cardiac myocardial cells in rats with heart failure
... promotes myocardial energy ...on myocardial energy metabolism and structure in a heart failure rat ...addition, myocardial tissue structure changes were observed under lighted and electron ... See full document
6
Original Article Qiliqiangxin improves cardiac function and attenuates cardiac remodeling in rats with experimental myocardial infarction
... NRG-1 is a member of the epidermal growth factor family, which plays a crucial role in the cardiovascular development and maintenance of structural and functional integrity of the adult heart. Xiao J et al. [15] found ... See full document
11
Impact of aging on cardiac function in a female rat model of menopause: role of autonomic control, inflammation, and oxidative stress
... and insulin resistance in all groups when compared with ...old rats (OC and OO) presented a higher left ventricular mass and increased left ventricular diameter during diastole when compared with young ... See full document
10
Original Article Effects of electroacupuncture at Shenting and Baihui on cAMP-PKA-CREB signaling pathways in rats with cognitive dysfunction caused by cerebral ischemia reperfusion
... Ferranti S, Després JP, Fullerton HJ, Howard VJ, Huffman MD, Judd SE, Kissela BM, Lackland DT, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Matchar DB, McGuire DK, Mohler ER 3rd, Moy CS, Muntner P, Mussolino ... See full document
8
Original Article Effects of glycyl-glutamine dipeptide supplementation on myocardial damage and cardiac function in rats after severe burn injury
... decreases myocardial damage in ischemia/reperfusion ...on myocardial damage in severe burn rats. Seventy-two Wistar rats were randomly divided into three groups: normal control (C), burned ... See full document
10
Overexpression of Interleukin-18 Aggravates Cardiac Fibrosis and Diastolic Dysfunction in Fructose-Fed Rats
... All rats were handled in accordance with the Animal Management Rules of the Ministry of Health, People’s Republic of China (documentation 55, 2001), and experimental protocol was approved by the Institutional ... See full document
6
Glucagon-Like Peptide 1 Protects against Hyperglycemic-Induced Endothelial-to-Mesenchymal Transition and Improves Myocardial Dysfunction by Suppressing Poly(ADP-Ribose) Polymerase 1 Activity
... cells that coexpress vWF was much greater than that in nondiabetic mice. In addition, GLP-1 treatment significantly reduced the percentage of vWF + /α-SMA + cells. The reason that we chose vWF in- stead of VE-cadherin in ... See full document
11
Proarrhythmic risk and determinants of cardiac autonomic dysfunction in collagen induced arthritis rats
... occur on different timescale. PRSA technique could synchronize all periodic components of the signal irre- spective of their frequency and timescale. It thus integrated all contributions of above mentioned mechanisms by ... See full document
8
<p>Liraglutide attenuates cardiac remodeling and improves heart function after abdominal aortic constriction through blocking angiotensin II type 1 receptor in rats</p>
... these changes, liraglutide signi fi cantly decreased the populations of macrophages and myo fi broblasts in the myocar- dium, which were accompanied by reduced protein levels of transforming growth factor beta1, ... See full document
13
Original Article Effects of myocardial mir-124 on the expression of insulin-like growth factor-1 (IGF-1) in hypothyroid rats
... the insulin-like growth fac- tor family and is present in most types of tis- sues in the ...of myocardial cells in hypothyroidism patients is affected by the TH level ... See full document
6
Original Article Effects of changes in the intestinal function of rats with intestinal dysfunction induced by new intestinal obstructions
... Wister rats, in which a homemade atraumatic intestinal clamp was used to externally op- press the ...study changes in intestinal histopathology, damage indexes of ileum mucosa, serum carbamyl ornithine ... See full document
12
Edaravone inhibits pressure overload-induced cardiac fibrosis and dysfunction by reducing expression of angiotensin II AT1 receptor
... anti- collagen type III monoclonal antibody (Sigma-Aldrich Co, St Louis, MO, USA), and a mouse anti-beta actin monoclonal antibody (Sigma-Aldrich Co), ... See full document
15
Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway
... iting fibrosis of the heart may be its inhibition of EndMT in the fibrotic ...the fibrosis while improve the endothelial ...the effects of RLX on the EndMT and whether another pathway mediates the ... See full document
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