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[PDF] Top 20 Original Article TNF-α -308G/A polymorphism associated with TNF-α protein expression in patients with diabetic nephropathy

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Original Article TNF-α -308G/A polymorphism associated with TNF-α protein expression in patients with diabetic nephropathy

Original Article TNF-α -308G/A polymorphism associated with TNF-α protein expression in patients with diabetic nephropathy

... mRNA expression level was low in the unacti- vated GMC [20], while it was upregulated with lipopolysaccharide (LPS) activation ...the expression of TNF-α [22]. In addi- tion, ... See full document

5

Original Article Association of -308G/A and -238G/A polymorphisms of TNF-α and osteosarcoma risk

Original Article Association of -308G/A and -238G/A polymorphisms of TNF-α and osteosarcoma risk

... of patients was the distant metastasis [11, ...gene expression and gene loss or loss of func- tion of anti-oncogene that leads to carcinogen- esis ...[14]. TNF-α is a peptide regulatory factor ... See full document

5

Original Article Tumor necrosis factor-α gene 308G/A polymorphism is not associated with esophageal squamous cell carcinoma risk in Kazakh patients

Original Article Tumor necrosis factor-α gene 308G/A polymorphism is not associated with esophageal squamous cell carcinoma risk in Kazakh patients

... the TNF-α-308A allele has an increased risk for several cancers, such as hepatocellular cancer, breast cancer, gastric cancer and breast ...the polymorphism of TNF-α- 308G/A is ... See full document

7

Original Article Roles of TNF-α, GSK-3β and RANKL in the occurrence and development of diabetic osteoporosis

Original Article Roles of TNF-α, GSK-3β and RANKL in the occurrence and development of diabetic osteoporosis

... addition, TNF-α is closely relat- ed to bone metabolism ...the TNF receptor ligand superfamily, playing an important role in bone metabolism; its metabolic imbalance is associated with bone ... See full document

10

Original Article Genetic polymorphisms of the TNF-α-308G/A are associated with metabolic syndrome in asthmatic patients from Hebei province, China

Original Article Genetic polymorphisms of the TNF-α-308G/A are associated with metabolic syndrome in asthmatic patients from Hebei province, China

... the patients with asthma, anthropometric and biochemical parameters were analyzed under the genotypes of ...asthma patients and an insulin resistance state in relation with the AA + GA genotypes of the ... See full document

8

The involvement of proinflammatory cytokines in diabetic nephropathy: Focus on interleukin 1 (IL-1), interleukin 6 (IL-6), and tumor necrosis factor-alpha (TNF-α) signaling mechanism

The involvement of proinflammatory cytokines in diabetic nephropathy: Focus on interleukin 1 (IL-1), interleukin 6 (IL-6), and tumor necrosis factor-alpha (TNF-α) signaling mechanism

... Diabetic nephropathy remains a major challenge in the field of medicine. Huge number of evidence now exist to prove that several proinflammatory cytokines are known to be involved in its mech- anism, ... See full document

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The Possible Role of the Incretin Enhancer Sitaglipten, in Renal Ischemic Reperfusion Injury in Type 2 Diabetes Mellitus

The Possible Role of the Incretin Enhancer Sitaglipten, in Renal Ischemic Reperfusion Injury in Type 2 Diabetes Mellitus

... Diabetes mellitus in rats were induced by administration of nicotinamide (NIC) (230 mg/kg, i.p.), 15 min prior to a single intraperitoneal (i.p.) injection of streptozotocin (65 mg/kg, STZ) dissolved in di-sodium citrate ... See full document

17

TNF α is crucial for the development of autoimmune arthritis in IL 1 receptor antagonist–deficient mice

TNF α is crucial for the development of autoimmune arthritis in IL 1 receptor antagonist–deficient mice

... RA patients can cause inflammatory arthritis in SCID mice ...receptor α (CD25), CD69, CD44, CD40 ligand (CD40L; also known as CD154), and OX40 (also known as CD134) (12) CD40L on T cells and its receptor on ... See full document

10

Original Article Tumor necrosis factor-α (TNF-α) and its receptor gene polymorphisms association with the susceptibility to papillary thyroid cancer in Chinese Han population

Original Article Tumor necrosis factor-α (TNF-α) and its receptor gene polymorphisms association with the susceptibility to papillary thyroid cancer in Chinese Han population

... Genetic polymorphism of TNFR2 A1466G was found to be predictive response in Japanese ESCC patients with a definitive 5-FU/CDDP-based ...of patients or experiments in vitro should be performed to ... See full document

9

Original Article Effects of nicotine on a rat model of early stage osteoarthritis

Original Article Effects of nicotine on a rat model of early stage osteoarthritis

... is associated with several limita- ...higher expression of α7nAChR in the syno- vial tissue of the nicotine-treated group com- pared to the saline-treated group, but no pub- lished literature supports these ... See full document

11

Original Article Increased HDAC3 and decreased miRNA-130a expression in PBMCs through recruitment HDAC3 in patients with spinal cord injuries

Original Article Increased HDAC3 and decreased miRNA-130a expression in PBMCs through recruitment HDAC3 in patients with spinal cord injuries

... The PBMCs RNA extraction was performed according to the TRIzol manufacturer’s protocol (Invitrogen, Carlsbad, CA, USA). Synthesis of cDNAs was performed by reverse transcription reactions with 2 μg of total RNA using ... See full document

8

Original Article Effect of TNF-α on osteoporosis by regulating the RANKL/OPG signaling pathway

Original Article Effect of TNF-α on osteoporosis by regulating the RANKL/OPG signaling pathway

... Osteoporosis (OP) is a chronic systemic skele- tal system disease, which is common in the elderly and menopausal women [1, 2]. With the natural loss of bone and menopause, taking drugs such as glucocorticoids, the ... See full document

7

Inhibiting TNF-α signaling does not attenuate induction of endotoxin tolerance

Inhibiting TNF-α signaling does not attenuate induction of endotoxin tolerance

... anti-TNF- α or anti-TNF- α receptor antibodies from the primary stimula- ...nant TNF- α in the presence of anti-TNF- α and anti-TNF- α receptors and ... See full document

9

on cell proliferation, apoptosis, and expression of SOST, β-catenin, Collagen II, and MMP13 in rat articular chondrocytes induced by TNF-α in vitro

on cell proliferation, apoptosis, and expression of SOST, β-catenin, Collagen II, and MMP13 in rat articular chondrocytes induced by TNF-α in vitro

... 19]. TNF-α is a cytokine secreted by activated macrophages with many biological functions, including regulating in- flammatory response, apoptosis, and antiviral ...with TNF-α to establish the ... See full document

9

Beneficial effect of TNF-α inhibition on diabetic peripheral neuropathy

Beneficial effect of TNF-α inhibition on diabetic peripheral neuropathy

... of diabetic peripheral neuropathy rats The rat model of DPN was generated as previously de- scribed [11] with a slight ...the diabetic animals were continuously fed with a high-fat, high-sugar diet for ... See full document

9

Review Article Association between TNF-α 238 G/A polymorphism and gastric carcinoma risk: a systematic review and a meta-analysis

Review Article Association between TNF-α 238 G/A polymorphism and gastric carcinoma risk: a systematic review and a meta-analysis

... with TNF-α 238 G/A ...or polymorphism” and “238 G/A or TNF-α or TNF or tumor necrosis factor” and “stomach carcinoma or stomach cancer or gastric cancer or gastric ... See full document

10

Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma

Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma

... that associated with tumor fibrosis are tumor promoting in ...As TNF-α also overexpressed in PSCs isolated from PDAC, we hypothesized that anti-TNF-α treatments will show anti- ... See full document

13

Antithrombotic activity of TNF α

Antithrombotic activity of TNF α

... by TNF-a in thrombus formation and growth in an in vivo mouse ...of TNF-a at doses found in sepsis transiently inhibits thrombus formation and delays arterial occlusion upon vascular ...the ... See full document

9

Allium hookeri root protects oxidative stress induced inflammatory responses and β cell damage in pancreas of streptozotocin induced diabetic rats

Allium hookeri root protects oxidative stress induced inflammatory responses and β cell damage in pancreas of streptozotocin induced diabetic rats

... increasing associated with various complications either at the macrovascular level causing coronary artery and cerebrovascular diseases or at the microvascular level causing renal failure, blind- ness, limb ... See full document

10

Normalization of the levels of inflammatory molecules in Mycobacterium smegmatis-infected U937 cells by fibrate pretreatment

Normalization of the levels of inflammatory molecules in Mycobacterium smegmatis-infected U937 cells by fibrate pretreatment

... of protein was extracted and electrophoresed on a sodium dodecyl sulfate polyacrylamide gel (Bio-Rad, Hercules, CA, ...The protein-containing membrane was blocked using 5% skim milk (Bio-Rad) and then ... See full document

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