[PDF] Top 20 Original Article The rs1447295 polymorphism in the 8q24 gene contributes to cancer risk, especially prostate cancer: a meta-analysis

... “the 8q24 gene”, “single nucleotide polymor- phism”, “rs1447295” and “cancer” to identify relevant articles on the ...tween rs1447295 C>A polymorphism and can- cer ... See full document

... first meta-analysis exploring the relationship of MSH3 rs26279 G > A polymorphism with over- all cancer ...A polymorphism was found to confer 10% to 27% increase in the risk ... See full document

... Prostate cancer is the fifth most common can- cer in the world and the second most common cancer in men ...tate cancer are still not well understood, which may has been one of the most ... See full document

... Tyrer J, Kolonel LN, Le Marchand L, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Goh C, Ahmed M, Go- vindasami K, Guy M, Tammela TLJ, Auvinen A, Wahlfors T, Schleutker J, Visakorpi T, ... See full document

... (AGTR1) gene A1166C polymorphism and risk of cancer but revealed in consistent ...AGTR1 gene A1166C polymorphism and risk of ...AGTR1 gene A1166C ... See full document

... The first identified member of the toll-like recep- tor family is the toll-like receptor 4 (TLR4), which can identify pathogen-associated molecular patterns (PAMPs) and damage-associated mo- lecular pattern (DAMPs). The ... See full document

... the risk of gastric cancer (GC) remain conflicting and have not been stud- ied in ...This meta-analysis was performed to clarify the association between CTLA-4+49A/G, -1661A/G and -1722T/C ... See full document

... XRCC3 gene plays crucial roles in DNA damage repairing that is closely involved in pathogenesis of tu- ...XRCC3 gene and Thr241Met poly- morphism in patients with ...this meta-analysis ... See full document

... nucleotide polymorphism (SNP) rs4245739 in MDM4 is associated with cancer ...date meta-analysis was performed to investigate the association between rs4245739 and cancer risk in ... See full document

... genetic polymorphism of methylenetetra- hydrofolate reductase (MTHFR) in exon 4 codon 677 (C/T) and the susceptibility to ovarian ...a meta-analysis of 12 studies involving 7876 controls and 5057 ... See full document

... colorectal cancer (CRC) have been assessed with several studies, but the conclusions were ...a meta-analysis to evaluate the impact of CASR polymorphisms on CRC risk and ...CRC risk was ... See full document

... and cancer risk has been widely investigated, while many publications have reported controversial ...a meta-analysis evaluating the association between CTLA-4 rs5742909 C>T ... See full document

... for meta-analysis, and the other nine studies involving nine polymorphisms (MMP2 rs2285053, MMP2 rs1477017, MMP2 rs17301608, MMP2 rs11639960, MMP3 11715A/6A, MMP3 1161A/G, MMP3 5356A/G, MMP9 rs17576, and ... See full document

... Several limitations should be considered in our study. First, cases and controls were selected from one hospital, which may not be represen- tative of other populations. Selection bias may exist in this study. Second, ... See full document

... this meta-analysis, which might cause publication ...precise analysis should be performed. Third, several factors such as gene–gene or gene–environment interaction may influence ... See full document

... for meta-analysis. Third, our analysis might overlook the possibility of gene–gene or SNP–SNP interactions or linkage disequilibrium between ...this gene polymorphism ... See full document

... of prostate cancer and it may make some difference ...lower risk populations where dietary or environmental risk may play a disproportionate impact (for example, in- cidence of prostate ... See full document

... were diverse and might affect the results of meta-analysis. Due to a lack of valid data pertaining to age and gender for all included studies, we could not evaluate their impacts on the pooled OR value. ... See full document

... liver cancer patients and 540 control subjects were select- ed, the mean age for all participants was ...Liver cancer cases were diag- nosed by combination of pathological examina- tion, ultrasound and ... See full document

... our meta- ...the meta-analysis, the sample size in each study or each type of cancer was very ...overall cancer risk, but did not perform stratified analysis based on ... See full document