[PDF] Top 20 Original Article Single nucleotide polymorphisms in VEGF gene are associated with an increased risk of osteosarcoma
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Original Article Single nucleotide polymorphisms in VEGF gene are associated with an increased risk of osteosarcoma
... of VEGF under hypoxic conditions is involved in prolonging the lifetime of malignant cell which play a critical role in tumor growth and invasion, and also play an important role in the development of metastases ... See full document
7
Vascular endothelial growth factor polymorphisms are associated with osteosarcoma susceptibility
... (VEGF) gene may contribute to osteosarcoma risk, but the results of previous studies have been inconsistent and ...three VEGF gene polymorphisms (+936C/T, –634 G/C, +1612 ... See full document
9
Original Article Single nucleotide polymorphisms of HER2 related to osteosarcoma susceptibility
... between single necleotide polymor- phisms (SNPs) of human epidermal growth factor receptor-2 (HER2) gene with osteosarcoma susceptibility in Chinese Han ...with osteosarcoma and 100 healthy ... See full document
6
Original Article NR1H4 gene single nucleotide polymorphisms are associated with susceptibility to colorectal polyps, ulcerative colitis and colorectal cancer
... major risk factor for colon cancer development [1], and cholecystectomy has been associated with right-sided colon cancer ...an increased bile acids (BA) load in the intestine, and higher relative ... See full document
9
Original Article Associations of LIM kinase1 (LIMK1) gene single nucleotide polymorphisms with prostate cancer susceptibility in Chinese population
... affect gene expression and disease susceptibility when locate in upstream or downstream from the gene ...rs710968 increased the risk of intracranial aneurysms [22], and this conclu- sion was ... See full document
10
Original Article Association between EPAS1 gene single nucleotide polymorphisms and risk and prognosis of renal clear cell carcinoma
... HIF controls several important genes just like vascular endothelial growth factor (VEGF), erythropoietin (EPO), endothelin-1 (ET-1) and nitric oxide synthase (NOS) etc. which were involved in the formation of new ... See full document
9
Original Article Screening of TRIM and TLR4 single nucleotide polymorphisms in patients with different period of clinical osteosarcoma in China
... with osteosarcoma, which may contribute to TRIM- 14 overexpression in osteosarcoma ...TLR4 gene correlate with many human disease, such as myeloproliferative disorders, infectious diseases and ... See full document
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Original Article Association between single nucleotide polymorphisms of the MTHFR gene and thromboangiitis obliterans
... methionine. Single nucleotide polymorphisms (SNP) of the MTHFR gene have been demonstrated to be correlated with decreased enzyme activity, eventually causing elevated homo- cysteine (Hcy) ... See full document
7
Original Article Identification of novel single nucleotide polymorphisms in androgen receptor gene in two families with complete androgen insensitivity syndrome
... is associated with an increased risk of developing testicular can- cer in males due to gene mutations ...AR gene likely con- tribute to the development of ovarian cancer [15], prostate ... See full document
6
Original Article An association between single nucleotide polymorphisms (SNPs) of -4719A/T (rs2619679) and -4601A/G (rs5030789) RAD51 gene and breast cancer
... berg equilibrium values with control values by the standard Chi-square test. Genotype fre- quencies in the study cases and the controls were compared by the Chi-square test. Gen- otype specific risks were estimated as ... See full document
6
Original Article Clinical significance of single nucleotide polymorphisms of adiponectin gene in Chinese benign prostatic hyperplasia patients
... closely associated with meta- bolic syndrome (MetS), which commonly associated with decreased serum adiponectin ...tag Single Nucleotide Polymorphisms (SNPs) of adiponectin gene ... See full document
6
Original Article The polymorphisms of oncostatin M receptor gene associated with increased risk of lung cancer
... The lung cancer patients enrolled in this study included 120 adenocarcinoma (ADC) and 111 squamous carcinoma (SCC) with complete fol- low-up. The single variate analysis indicated rs2292016 had no relationship ... See full document
8
Original Article Interleukin-31 single nucleotide polymorphisms are significantly associated with endometrial cancer in Chinese Han women
... IL-31 gene poly- morphisms have been associated with several ...complete gene and identified 3 most common haplotypes that were present in ...IL-31 gene haplotype is strongly associated ... See full document
10
Original Article Association of single nucleotide polymorphisms of DNA repair gene and susceptibility to pancreatic cancer
... mon polymorphisms can play a role in an indi- vidual’s genetic susceptibility to cancer ...XRCC4 gene may lead to decrease or loss of its DNA repair capacity and confer the variation in susceptibility to ... See full document
6
Original Article Polymorphisms in TP53 are associated with risk and survival of osteosarcoma in a Chinese population
... [24] Schildkraut JM, Goode EL, Clyde MA, Iversen ES, Moorman PG, Berchuck A, Marks JR, Lis- sowska J, Brinton L, Peplonska B, Cunningham JM, Vierkant RA, Rider DN, Chenevix-Trench G, Webb PM, Beesley J, Chen X, Phelan C, ... See full document
6
Original Article HSG single nucleotide polymorphisms associated with serum lipids in Chinese patients with hypertension
... the gene and in turn play an important role in the expression regulation of ...the increased triglycer- ide content in 25-month-old rats was followed by the down-regulation of HSG/Mfn2 and the decreased ... See full document
9
Original Article Association between XRCC1 and ERCC2 gene polymorphisms and development of osteosarcoma
... XRCC1 gene (Arg194Trp, rs1799782; Arg280His rs25489; Arg399Gln rs25487) and one SNP in ERCC2 gene (Lys751Gln rs13181) with the susceptibility to ...confirmed osteosarcoma and 275 control subjects ... See full document
7
DNA repair gene variants are associated with an increased risk of myelodysplastic syndromes in a Czech population
... previously associated with bladder cancer in work by Andrew et ...a gene that encodes another transmembrane protein, which belongs to the ABC (ATP-binding cassette) protein transporter ... See full document
6
Novel single-nucleotide polymorphisms in the calsequestrin-1 gene are associated with Graves’ ophthalmopathy and Hashimoto’s thyroiditis
... Results: DNA samples from 300 patients and 106 control subjects (100 males, 306 females) with GO (n=74), GH (n=130), HT (n=96) and control subjects (n=106) were genotyped for the SNPs rs74123279, rs3747673 (n=405), and ... See full document
10
Genotyping panel for assessing response to cancer chemotherapy
... on single nucleotide primer exten- sion that has been successfully adapted to the Applied Biosystems 3730 DNA Analyzer ...Three single nucleotide polymorphisms, rs42427 in the APC ... See full document
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