[PDF] Top 20 Original Article Zerumbone induces G1 cell cycle arrest and apoptosis in cervical carcinoma cells
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Original Article Zerumbone induces G1 cell cycle arrest and apoptosis in cervical carcinoma cells
... addition, zerumbone has subsequently been shown to inhibit prolifera- tion in a variety of cancer cell, but not in normal ...that zerumbone treatment of cervical, liver and pancreatic cancer ... See full document
8
Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells
... eukaryotic cells is controlled at specific stages of the cell cycle, particularly at the Gl to S and G2 to M transition and affected through the peri- odic activation and inactivation of a series of ... See full document
12
Original Article Puerariae radix flavone induces cell cycle arrest and apoptosis of NB4 cells accompanied with JNK and mitochondrial pathway activation
... APL cell line NB4 and to explore the potential mechanisms. Methods: NB4 cells were exposed to various concentrations (0, 10, 30, 50 µg/ml) of ...PRF. Cell viability was mea- sured by MTT assay. The ... See full document
9
Casticin induces apoptosis and G0/G1 cell cycle arrest in gallbladder cancer cells
... Flavonoids, which are plentiful in components of human diets, such as fruits and vegetables, exhibit extensive biolog- ical effects, including anti-cancer, anti-inflammatory, anti- oxidant and anti-viral activities [7]. ... See full document
10
Original Article Combination of metformin and valproic acid synergistically induces cell cycle arrest and apoptosis in clear cell renal cell carcinoma
... bated for 24 h till all cells sufficient attached to the plate. Before the drug treatment, the cul- ture medium changed as RPMI 1640 medium contained 2% FBS. After 24 h, 48 h, and 72 h treatment with varying doses ... See full document
6
Original Article TRIM29 functions as an oncogene in gastric cancer and is regulated by miR-185
... GC cells. In addition, down-regulation of TRIM29 in GC cells blocks cell cycle progression by arresting cells in ...induced apoptosis of GC ... See full document
9
Original Article Downregulation of RECQL4 inhibits gastric cancer cell proliferation and induces cell cycle arrest at G0/G1 phase
... SGC-7901 cells. Moreover, cell cycle analysis showed that inhibition of RECQL4 induced cell cycle arrested in G0/G1 phase in AGS and SGC-7901 ...GC cell proliferation and ... See full document
12
Original Article TRIM66 knockdown inhibits cell growth, but induces cell cycle arrest and apoptosis of hepatocellular carcinoma cells
... Hepatocellular carcinoma (HCC) has become a major health problem as it is one of the most common malignancies and the third leading cause of cancer-related deaths worldwide [1, ... See full document
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Original Article Salidroside induces cell cycle arrest and apoptosis in human cervical cancer SiHa cells
... SiHa cells were treated with or without different concentrations of salidroside for 48 h, and their morphology was observed under a light micro- ...control cells without salidroside treatment displayed a ... See full document
9
Original Article Simvastatin suppresses cell migration and invasion, induces G0/G1 cell cycle arrest and apoptosis in osteosarcoma cells
... for cell existence and ...MNNG/HOS cells were treated with various concentrations of Sim (0, 8, 16 μM) for 48 h, as shown in Figure 4C, 4D and 4F, the expressions of PI3K (p110β) and phospho-Akt (p-Akt) ... See full document
12
Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells
... related cell apoptotic mole- cules in the knockdown of TMPO-induced cell apop- tosis, the effect of TMPO silencing on two classical cell apoptotic molecules caspase-3 and PARP was examined by western ... See full document
8
Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cells
... DMSO and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphe- nyltetrazolium bromide (MTT) were obtained from Sigma-Aldrich (M2128, St. Louis, MO, USA). Fetal bovine serum and RIPM1640 were purchased from Gibco (Grand Island, NY, ... See full document
13
Quercetin: A Promising Flavonoid with a Dynamic Ability to Treat Various Diseases, Infections, and Cancers
... There are several cardiovascular benefits associated with quercetin. Much of the evidence remains in murine models and the mechanisms of action have not been resolved as of yet. The severity of ischemia-reperfusion had ... See full document
13
Morus rubra Extract Induces G1 Cell Cycle Arrest and Apoptosis in Human Lung and Prostate Cancer Cells
... Then, cells were washed 2 times with assay buffer and finally, each cell pellet was gently resuspended in 500 µL of assay ...10000 cells per sample were collected and analyzed on a flow ... See full document
8
Curcumol: From Plant Roots to Cancer Roots
... of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several ... See full document
10
<p>MicroRNA-30a-3p inhibits the progression of lung cancer via the PI3K/AKT by targeting DNA methyltransferase 3a</p>
... A549 cells overexpression miR-30a-3p or siDNMT3a, resulting in inhibition of cell proliferation and cell cycle ...p38-involved cell cycle regulates expression of p21CIP1, ... See full document
10
Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells
... cancer cells were seeded in a six-well plate and allowed to adhere overnight before treatment with various concentra- tions of Artonin E (3, 10, and 30 µ M) at various time ...adherent cells were collected ... See full document
15
Effect of magnetic Fe3O4 nanoparticles with 2-methoxyestradiol on the cell-cycle progression and apoptosis of myelodysplastic syndrome cells
... SKM-1 cells and its underlying ...assay. Cell-cycle distribution and apoptosis were assessed by flow ...of cell-cycle marker protein was measured by Western ...SKM-1 cells ... See full document
7
Lycorine induces cell-cycle arrest in the G0/G1 phase in K562 cells via HDAC inhibition
... Histone acetylation and deacetylation regulate the chromatin structure and gene transcription. Dysregu- lation of their function has been associated with human cancer development. Recent studies have uti- lized HDAC as a ... See full document
6
Expressions of Long Non Coding RNAs in Carcinogenesis of Cervix: A Review
... transitional cell carcinoma with high specific- ity and sensitivity [82] ...squamous cell carcinoma, tongue squamous cell carcinoma, breast cancer, gastric cancer, ovarian ... See full document
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