[PDF] Top 20 Origins of Cdx1 regulatory elements suggest roles in vertebrate evolution

... chicken Cdx1 (Gaunt et ...chicken Cdx1/lacZ reporter construct expressed in trans- genic mouse embryos (Gaunt et ...the Cdx1/lacZ reporter resulted in substantial loss of lacZ expression in ... See full document

... in vertebrate evolution because it ushered the transition from a sessile, filter feeder such as am- phioxus into an active predator, facilitating vertebrate radiation into new environments (Northcutt ... See full document

... large regulatory landscapes (>50 kb) ...of regulatory complexity ...of regulatory regions during vertebrate evolution (and/or a decrease in these regions in amphioxus)—particularly ... See full document

... A major conceptual problem is to understand how actin can be persuaded to polymerize in a ring under the plasma mem- brane to form the walls of the macropinocytic cup. This requires organization of actin polymerization ... See full document

... brate evolution, we will need to validate their contribution to vertebrate ...the vertebrate gut microbiome culture collection can provide added opportunities to test specific ... See full document

... the identification of regulatory elements (Wasserman et al., 2000; Yuh et al., 2002). We attempted to use conservation to direct the further dissection of kn Mel 1-2330 to define a minimal regulatory ... See full document

... LAVA elements within the gibbon genome is a hallmark of the increased genomic plasticity in the gibbon lineage and contributes to the enhanced structural variation within the gibbon ...FVA elements. These ... See full document

... While identifying sleep in jellyfish and molluscs opens the door for studies for sleep function, rhythmic circadian behavior or gene expression has been identified in many other systems that have not been analysed for ... See full document

... Fibronectins are large disulphide-linked dimers encoded by a single gene. There are many forms of fibronectin formed through alternative splicing and the resulting proteins are modular in design with many functionally ... See full document

... during vertebrate evolution ...the vertebrate gene duplications occurred after the divergence of prevertebrates from invertebrate ...the evolution of this ... See full document

... extant vertebrate, the sea ...represent vertebrate- specific innovations, such as in cranial ectodermal placodes and the neural crest; whereas others represent structures characteristic of chordates, ...the ... See full document

... Like earlier mentioned, agile development teams often work with the Scrum method. The Scrum method enables a team to, for example, self-regulate their work (Moe, Dingsøyr, & Dybå, 2010). Scrum is a development ... See full document

... data suggest that Sox2-class factors are essential for early neuroectoderm cells to consolidate their neural identity during secondary steps of neural differentiation ... See full document

... the vertebrate gill may have been predominantly acid-base regulation with a small role in gas ...early evolution of the vertebrate ...ancestral vertebrate gill was acid-base relevant ... See full document

... evolution of animal morphology (e.g. Grenier and Carroll, 2000; Grandien and Sommer, 2001). Bapx1 (Nkx3.2) is an evolutionarily conserved homeobox-containing gene that belongs to the NK-2 family of transcription ... See full document

... Other sequences yield abundant gene products, but are nevertheless cryptic in the sense captured by our model, as a result of epistatic interactions that attenuate their pheno- typic effects (Segre et al. 2004; Carlborg ... See full document

... The scenarios proposed are: 1 a single 265 origin of stomata in the ancestor of all extant land plants, but with total loss in the ancestor of 266 the stomataless liverwort clade Chen et[r] ... See full document

... Breast cancer is not a single disease, but rather is composed of distinct subtypes associated with different clinical outcomes. Understanding this heterogeneity is key for the development of target- ed ... See full document

... To understand the structural basis for the activating role of the PDZ domain in regulating the activity of Prc, we have determined a set of crystal structures in the unliganded resting state of Prc, alone or in complex ... See full document

... as origins of knowledge about the fauna by the studied students, converging with the results of previous studies that em- phasized the role of schooling in the processes of knowledge acquisition regarding animals ... See full document