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[PDF] Top 20 Ovarian Cancer. What is ovarian cancer?

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Ovarian Cancer. What is ovarian cancer?

Ovarian Cancer. What is ovarian cancer?

... The other important goal of surgery is to remove as much of the tumor as possible − this is called debulking. Debulking is very important in any patient with ovarian cancer that has already spread widely ... See full document

63

TGFBI promoter hypermethylation correlating with paclitaxel chemoresistance in ovarian cancer

TGFBI promoter hypermethylation correlating with paclitaxel chemoresistance in ovarian cancer

... Epigenetic alterations play an important role in the initiation and progression of cancer [6-8]. Hypermethy- lation of CpG rich islands in promoter regions of genes has been characterized as a common epigenetic ... See full document

6

Response to microtubule-interacting agents in primary epithelial ovarian cancer cells

Response to microtubule-interacting agents in primary epithelial ovarian cancer cells

... the cancer cells took over the culture. Ovarian cancer cells grew in vitro as to acquire a monolayer distribution with the typical epithelial cobblestone morphology (Figure ...most ovarian ... See full document

10

Original Article Dihydrofolate reductase as a predictor for poor response to platinum-based chemotherapy in epithelial ovarian cancer

Original Article Dihydrofolate reductase as a predictor for poor response to platinum-based chemotherapy in epithelial ovarian cancer

... an cancer following surgery ...epithelial ovarian cancer ...favor ovarian cancer ...in ovarian cancer tissues, which is a valuable biomarker to predict plati- num-based ... See full document

8

Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let 7 miRNA and miR 200

Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let 7 miRNA and miR 200

... of ovarian cancer, despite recent progress in chemotherapeutic treatments, the diagnosis of late stage disease is associated with a five-year survival rate of ...when ovarian cancer is ... See full document

12

Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients

Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients

... chemotherapy was evaluated retrospectively according to the World Health Organisation response evaluation criteria [31]. The evaluation was based on data from medical records describing patient ’ s clinical condition and ... See full document

9

miRNA expression profiling in formalin-fixed paraffin-embedded endometriosis and ovarian cancer samples

miRNA expression profiling in formalin-fixed paraffin-embedded endometriosis and ovarian cancer samples

... For the validation of the most relevant altered miRNAs, we selected a subset of 17 normal samples, 33 endometriosis samples and 28 ovarian cancer samples. We used a two-step qRT-PCR. cDNA was generated ... See full document

14

Endometriosis and ovarian cancer - what they have in common?

Endometriosis and ovarian cancer - what they have in common?

... Endometriosis-Related Ovarian Neoplasms (ERONs) [18]. Besides ovarian cancer, several other tumors were also observed in women with endometriosis, including endometrial stromal sarcoma [19], ... See full document

10

Meeting report from the 2018 12th Biennial Ovarian Cancer Research Symposium detection and prevention of ovarian cancer

Meeting report from the 2018 12th Biennial Ovarian Cancer Research Symposium detection and prevention of ovarian cancer

... Dr Naoko Sasamoto (Brigham and Women’s Hospital) and colleagues presented their efforts on improving the efficiency and accuracy of using CA125 as a prediction method. They hypothesized that the distinct personal ... See full document

5

No Sib Pair Concordance for Breast or Ovarian Cancer in BRCA1 Mutation Carriers

No Sib Pair Concordance for Breast or Ovarian Cancer in BRCA1 Mutation Carriers

... and ovarian cancers are both expressions of BRCA1 germ-line ...breast cancer, or when she might do ...of what kind of cancer a BRCA mutation carrier may contract has been discussed ... See full document

5

Drug–target–disease network analysis of gene–phenotype connectivity for genistein in ovarian cancer

Drug–target–disease network analysis of gene–phenotype connectivity for genistein in ovarian cancer

... Only two ovarian carcinoma studies were included in cBio- Portal (Version 1.13.1). The seven genes (CDKN1B, PTEN, EGFR, MAPK1, MAPK3, PIK3CA, and AKT1) associated with the ovarian cancer pathway were ... See full document

8

<p>Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells</p>

<p>Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells</p>

... Ovarian cancer is the most common gynecological cancer and is the most deadly female tumor in the developed ...American Cancer Society, in 2018, there were 22,240 new diagnosed cases of ... See full document

13

Profile of vintafolide (EC145) and its use in the treatment of platinum-resistant ovarian cancer

Profile of vintafolide (EC145) and its use in the treatment of platinum-resistant ovarian cancer

... a better understanding of ovarian cancer biology will allow us to consider new molecular targeted agents. A number of promising molecular targeted agents have been the focus of recent clinical trials, ... See full document

8

MiR-1207 overexpression promotes cancer stem cell–like traits in ovarian cancer by activating the Wnt/β-catenin signaling pathway

MiR-1207 overexpression promotes cancer stem cell–like traits in ovarian cancer by activating the Wnt/β-catenin signaling pathway

... in ovarian cancer activated Wnt/β-catenin signaling by directly targeting and suppressing secreted Frizzled-related protein 1 (SFRP1), AXIN2 and inhibitor of β-catenin and TCF-4 (ICAT), which are vital ... See full document

13

&lt;p&gt;Co-Delivery of Curcumin and Paclitaxel by &amp;ldquo;Core-Shell&amp;rdquo; Targeting Amphiphilic Copolymer to Reverse Resistance in the Treatment of Ovarian Cancer&lt;/p&gt;

<p>Co-Delivery of Curcumin and Paclitaxel by &ldquo;Core-Shell&rdquo; Targeting Amphiphilic Copolymer to Reverse Resistance in the Treatment of Ovarian Cancer</p>

... experimental results, PTX and curcumin exert potent anti- ovarian cancer effects in vitro and can help reduce dosage and minimize side effects of cytotoxic therapies. The combined treatment with PTX and ... See full document

15

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.

... and Cancer Research Initiatives Foundation; MAY: National Institutes of Health (R01-CA122443, P30-CA15083, P50-CA136393); Mayo Foundation; Minnesota Ovarian Cancer Alliance; Fred ...MCC: ... See full document

37

SHP2 overexpression enhances the invasion and metastasis of ovarian cancer in vitro and in vivo

SHP2 overexpression enhances the invasion and metastasis of ovarian cancer in vitro and in vivo

... in ovarian cancer has not yet been ...in ovarian cancer tissue samples and 60 matched normal ovarian tissue samples from 60 patients with ovarian epithelial cancer, and we ... See full document

11

Ovarian Cancer: A Case Report

Ovarian Cancer: A Case Report

... the ovarian cancer that has been ...of ovarian cancer is ...the cancer has metastasized to other parts of the ...with ovarian cancer will undergo further tests to ... See full document

14

Ovarian Cancer (Event Driven)

Ovarian Cancer (Event Driven)

... the ovarian cancer market? What factors are driving the market for ovarian cancer therapies? What factors are constraining the market for ovarian cancer therapies? ... See full document

7

Plasma levels of lysophosphatidic acid in ovarian cancer versus controls: a meta-analysis

Plasma levels of lysophosphatidic acid in ovarian cancer versus controls: a meta-analysis

... Ovarian cancer (OC) is the deadliest among gynecological cancers, with 5-year survival rates ranging between 30-50 ...common cancer worldwide, and the age-standardized incidence rates range from more ... See full document

9

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