[PDF] Top 20 The pathogenesis and immunoregulation of the inflammatory response in the central nervous system
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The pathogenesis and immunoregulation of the inflammatory response in the central nervous system
... XVl ABB RE VIA TIO NS ACTH adrenocorticotrophic hormone BBB blood brain barrier B cell B lymphocyte BSA CFA CNS ConA CREAE CsA CSF CT EAE EAN ELAM-1 ELISA FACS FCS FITC bovine serum albu[r] ... See full document
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Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2
... in response to even minor path- ological conditions in the CNS ...in response to brain insults, may contribute to the neurodegenerative processes ...pro- inflammatory cytokines, such as TNF-α and ... See full document
12
Apoptosis in the Mouse Central Nervous System in Response to Infection with Mouse-Neurovirulent Dengue Viruses
... The pathogenesis of severe DEN disease remains poorly ...pathological response to DEN virus infection in vivo remains ...in response to DEN virus infection in vitro (7, ...model system for the ... See full document
7
Mice with different susceptibility to tick-borne encephalitis virus infection show selective neutralizing antibody response and inflammatory reaction in the central nervous system
... Results: An animal model of TBE based on BALB/c-c-STS/A (CcS/Dem) recombinant congenic mouse strains showing different severities of the infection in relation to the host genetic background was developed. After ... See full document
13
Nogo receptor complex expression dynamics in the inflammatory foci of central nervous system experimental autoimmune demyelination
... less inflammatory burden of the phase, while the neuronal reappearance might be con- nected to axonal remodeling and plasticity of corticosp- inal tract found during EAE rehabilitation period ...plasticity ... See full document
13
Recruitment and Retention of B Cells in the Central Nervous System in Response to Alphavirus Encephalomyelitis
... immune response, mirroring the CLNs, but small numbers of Ki-67 ⫹ B cells were detected for at least 6 months after ...the inflammatory response wanes and there is a steady decline in production of ... See full document
10
Central Nervous System Extracellular Matrix as a Therapeutic Bioscaffold for Central Nervous System Injury
... commonly includes (8) an inflammatory response (12), calcium mediated damage (13), glutamate excitotoxicity (14), vascular disruption (15), and apoptosis (5). In the later phase of secondary degeneration, ... See full document
166
Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration
... Lipopolysaccharide (LPS)-induced endotoxemia model A previously described model for systemic bacterial infection-induced CNS inflammation was employed in which mice were given either single or dual, staggered injections ... See full document
16
Impairment of autophagy in the central nervous system during lipopolysaccharide-induced inflammatory stress in mice
... However there are various regimens followed in mice. Among the acute treatments, the most frequently encoun- tered are i.p. LPS injection of 0.5, 1 or 5 mg/kg and sacrifice of animals after one hour to ten days. In that ... See full document
16
Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis
... The potential significance of B cell persistence in the MS CNS, including within meningeal immune-cell col- lections, is highlighted by the growing recognition that B cells may contribute to disease-relevant immune re- ... See full document
11
Central nervous system melanoma metastasis. Experimental studies on pathogenesis, diagnosis and therapy.
... In 1999 Holash et al. reported on the phenomenon of vessel co-option 8 using an animal glioma model. The authors described that in this model initial co-option of pre-existent vessels occurred, followed by vessel ... See full document
161
The response of the mature central nervous system to traumatic brain injury
... While astrocytes facilitate brain function in an uninjured brain, whether astrocytes play an overall beneficial or adverse function after brain injury remains unclear. Astrocytes undergo a stereotypical sequence of ... See full document
238
Drugs Acting on Central Nervous System
... A number of unwanted effects are common to most clinically useful inhaled anaesthetics; however, each agent also has additional unwanted effects. • Cardiovascular system. Most agents, particularly halothane, ... See full document
59
Is Ghrelin Synthesized in the Central Nervous System?
... the central nervous system, where ghrelin signaling regulates a vast variety of physiological functions [ ...particular, central actions of ghrelin play a major role in the regulation of the ... See full document
18
REGENERATION AND REPAIR OF THE CENTRAL NERVOUS SYSTEM
... We have conducted the only experiment to date on autonomic/somatic specificity of synapses made by sprouting axons. We caused the corticospinal tract (which normally synapses on very few spinal, sympathetic ... See full document
7
Reversible developmental stasis in response to nutrient availability in the Xenopus laevis central nervous system
... Many organisms confront intermittent nutrient restriction (NR), but the mechanisms to cope with nutrient fluctuations during development are not well understood. This is particularly true of the brain, the development ... See full document
11
HYPERVITAMINOSIS A-INDUCED CENTRAL NERVOUS SYSTEM DEFECTS
... Data obtained from histological studies of the lumbar vertebrae of control and experimental fetuses showed a thin layer of connective tissue covering the vertebral canal and spinal cord. The vertebral laminae and ... See full document
6
Central Nervous System Control of Glucose Homeostasis
... The central administration of macronutrients such as glucose or oleic acid de- creases blood glucose and insulin ...Like central insulin action, the central effect of circulating macronutrients on ... See full document
8
Agonist-antagonist interactions in the central nervous system
... In general glycine and GABA depress the excitation of Renshaw cells by glutamate, aspartate, DLH and acetylcholine to the same extent, thus the small degree of selectivity of HAP as an e[r] ... See full document
227
The signalling and function of EB12 in the central nervous system
... W hile th e cu rren t study provided considerable insight into th e basic biology, signalling and function of EBI2 in th e CNS th e re are certain lim itations th a t should be addressed. Firstly, th e role o f EBI2 ... See full document
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