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[PDF] Top 20 Towards a Personalized Cancer Gene Therapy: A Case of Clear Cell Renal Cell Carcinoma

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Towards a Personalized Cancer Gene Therapy: A Case of Clear Cell Renal Cell Carcinoma

Towards a Personalized Cancer Gene Therapy: A Case of Clear Cell Renal Cell Carcinoma

... ideal cancer gene therapy would selectively destroy the cancer nodules with negligible effects on the surrounding not yet compromised ...the cancer but not in the normal ...commander ... See full document

8

Ovarian metastasis of clear cell renal cell carcinoma: A case report

Ovarian metastasis of clear cell renal cell carcinoma: A case report

... for clear cell renal cell carcinoma (RCC) occurring 21 years ago; she currently presented with a bilateral ovarian ...was clear cell carci- ...be clear cell ... See full document

5

Case Report Sporadic renal hemangioblastoma with CA9, PAX2 and PAX8 expression: diagnostic pitfall in the differential diagnosis from clear cell renal cell carcinoma

Case Report Sporadic renal hemangioblastoma with CA9, PAX2 and PAX8 expression: diagnostic pitfall in the differential diagnosis from clear cell renal cell carcinoma

... sporadic renal hemangioblastoma have been ...a case that might cause the diagnostic ...a renal mass by periodic medical ...VHL gene mutation, hypermethylation and loss of heterozygosity of ... See full document

8

Case Report Synchronous renal neoplasms: clear cell renal cell carcinoma, papillary renal cell carcinoma, and multilocular cystic renal cell neoplasm of low malignant potential in the same kidney

Case Report Synchronous renal neoplasms: clear cell renal cell carcinoma, papillary renal cell carcinoma, and multilocular cystic renal cell neoplasm of low malignant potential in the same kidney

... cystic renal cell carcinoma (MCRCC), which was classified as a rare sub- type of CCRCC with an excellent ...cuboidal clear cells, and the thin septas between the cysts contain groups of ... See full document

6

A gallbladder tumor revealing metastatic clear cell renal carcinoma: report of case and review of literature

A gallbladder tumor revealing metastatic clear cell renal carcinoma: report of case and review of literature

... cell carcinoma; CEA is expressed only in gallbladder carcinomas ...our case, tumor cells expressed vimen- tin and ...Metastatic clear cell RCC should also be differentiated from a ... See full document

6

Review Article Role of hypoxia-inducible factor in clear cell renal cell carcinoma and its application in targeted therapy

Review Article Role of hypoxia-inducible factor in clear cell renal cell carcinoma and its application in targeted therapy

... Currently, renal cell carcinoma (RCC) accounts for 3% of all adult tumors and 95% of all renal malignancies ...are clear cell renal cell carcinomas (CCRCCs, ... See full document

9

Identification of clear cell renal cell carcinoma and oncocytoma using a three gene promoter methylation panel

Identification of clear cell renal cell carcinoma and oncocytoma using a three gene promoter methylation panel

... cases, renal mass biopsy is mandatory, for adequate risk stratification, which requires accurate diagnosis [4, ...in renal mass biopsy, it is non-diagnostic in approximately 15% of patients, more frequently ... See full document

9

The Gene Master Regulators (GMR) Approach Provides Legitimate Targets for Personalized, Time-Sensitive Cancer Gene Therapy

The Gene Master Regulators (GMR) Approach Provides Legitimate Targets for Personalized, Time-Sensitive Cancer Gene Therapy

... tissue in a case of metastatic clear cell renal cell carcinoma, a case of papillary thyroid cancer and two 356. cases of prostate cancer[r] ... See full document

20

Alteration of ASIC1 expression in clear cell renal cell carcinoma

Alteration of ASIC1 expression in clear cell renal cell carcinoma

... of the immunohistochemical ASIC1 protein expression. CCRCC tissues and matched adjacent normal tissues from 75 patients were included in this study. The clinicopatho- logical characteristics of the study population and ... See full document

7

Expression of KI67, P53 and MUC1 in Renal Cell Carcinoma in Correlation with Nuclear Grade

Expression of KI67, P53 and MUC1 in Renal Cell Carcinoma in Correlation with Nuclear Grade

... for clear cell variety of ...in case of grade 1 tumours, 65% in case of grade 2 tumours and 46% in case of grades III-IV ...of clear cell type of ... See full document

174

Cell death-related molecules and biomarkers for renal cell carcinoma targeted therapy

Cell death-related molecules and biomarkers for renal cell carcinoma targeted therapy

... which clear cell RCC (ccRCC) is the most frequent (75– 80%), followed by papillary RCC (pRCC; 15%) and chro- mophobe RCC (chRCC; 5%) [6], and biallelic von-Hippel Lindau (VHL) gene defects occur in ... See full document

15

Crosstalk between VEGFR and other receptor tyrosine kinases for TKI therapy of metastatic renal cell carcinoma

Crosstalk between VEGFR and other receptor tyrosine kinases for TKI therapy of metastatic renal cell carcinoma

... Three generations of EGFR-TKIs were developed. The first generation of EGFR-TKIs such as erlotinib or gefi- tinib, exhibit resistance after several months of treatment in patients with EGFR-activating mutations, ... See full document

9

Construction of a novel gene-based model for prognosis prediction of clear cell renal cell carcinoma

Construction of a novel gene-based model for prognosis prediction of clear cell renal cell carcinoma

... To the best of our knowledge, there has not been any study using the screening methods like ours to iden- tify the upregulated DEGs with HR > 1 and downregu- lated DEGs with HR < 1. The method can exclude some ... See full document

18

Original Article Expressions of miR-193b and miR-338-3p in renal clear-cell carcinoma cells and their effects on biological function

Original Article Expressions of miR-193b and miR-338-3p in renal clear-cell carcinoma cells and their effects on biological function

... in renal clear-cell carcinoma ...in renal clear-cell ...pancreatic cancer cells, while miR-338-3p regulates the proliferation, invasion, and other biological ... See full document

9

Upregulation of Rarb, Rarg, and Rorc Genes in Clear Cell Renal Cell Carcinoma

Upregulation of Rarb, Rarg, and Rorc Genes in Clear Cell Renal Cell Carcinoma

... of clear-cell renal-cell carcinoma and adjacent morphologically normal tissues were taken during surgical resection from patients with primary ccRCC without neoadjuvant ... See full document

9

A four-gene signature predicts survival in clear-cell renal-cell carcinoma

A four-gene signature predicts survival in clear-cell renal-cell carcinoma

... provide risk assessment and survival analysis in cancer datasets using a biomarker gene list as an input [40]. In databases provided by SurvExpress, TCGA (KIRC) and ZHAO database contain much larger samples ... See full document

15

Thyroid Metastases from Clear Cell Renal Carcinoma: Presentation of an Unusual Case and Literature Review

Thyroid Metastases from Clear Cell Renal Carcinoma: Presentation of an Unusual Case and Literature Review

... of Cancer Therapy the best laboratory tool available for a correct defferential diagnosis is immuno- ...Epithelial Cell Membrane Antigen (EMA), Vimentin (variably), Renal Cell ... See full document

7

Somatic mutations in renal cell carcinomas from Chinese patients revealed by targeted gene panel sequencing and their associations with prognosis and PD-L1 expression

Somatic mutations in renal cell carcinomas from Chinese patients revealed by targeted gene panel sequencing and their associations with prognosis and PD-L1 expression

... : renal cell carcinoma; ccRCC : clear cell renal cell carcinoma; PRCC : papil- lary renal cell carcinoma; ChRCC : chromophobe renal ... See full document

6

A nomogram based on 9-lncRNAs signature for improving prognostic prediction of clear cell renal cell carcinoma

A nomogram based on 9-lncRNAs signature for improving prognostic prediction of clear cell renal cell carcinoma

... urothelial carcinoma associated 1 (UCA1), which could pro- mote aggressiveness of cancer cell, is associated with prog- nosis of multiple tumor such as bladder cancer, colorectal ... See full document

15

Original Article Identification of hypomethylation profile of Ki-67 promoter in vitro and in vivo

Original Article Identification of hypomethylation profile of Ki-67 promoter in vitro and in vivo

... in cancer diagnosis, but little is known about its gene regula- ...Ki-67 gene regulation, we performed bisulfite sequencing and methylation specific PCR (MSP) to generate the methylation profile of ... See full document

9

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