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[PDF] Top 20 Potential of Mesenchymal Stem Cell based application in Cancer.

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Potential of Mesenchymal Stem Cell based application in Cancer.

Potential of Mesenchymal Stem Cell based application in Cancer.

... various cancer models, to list a few, IFN-ß on pancreatic cancer, 39 IL-12 on melanoma and hepatoma, 51 IFN-α on melanoma, 52 IFN-r on leukemia, 53 IL-2 on glioma, 34 NK4 on lung cancer 54 and TRAIL ... See full document

9

Application of mesenchymal stem cells for therapeutic agent delivery in anti tumor treatment

Application of mesenchymal stem cells for therapeutic agent delivery in anti tumor treatment

... breast cancer cells by activating the Wnt signaling pathway (Lin et ...metastatic potential of gastric cancer cells (Gu et ...tumor cell resistance to ...gastric cancer cells by ... See full document

10

Zoledronic acid prevents the tumor-promoting effects of mesenchymal stem cells via MCP-1 dependent recruitment of macrophages

Zoledronic acid prevents the tumor-promoting effects of mesenchymal stem cells via MCP-1 dependent recruitment of macrophages

... the potential ability for self-renewal, long- term viability, and capacity for differentiation toward a variety of cell types ...breast cancer cells [8]. MSC may sustain cancer cell ... See full document

11

Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis

Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis

... ovarian cancer treatment. Indeed, targeting stem/progenitor cells has emerged as a novel potential approach to battle ovarian cancer ...target stem/progenitor cells [35, 36], and the ... See full document

14

Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumonia

Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumonia

... By direct engineering methods, therapeutic agents (bio-molecules and drugs) are directly loaded into exosomes isolated from confident source cells, and then these exosomes are delivered into the tissue of target. By ... See full document

10

EMT, CTCs and CSCs in tumor relapse and drug-resistance

EMT, CTCs and CSCs in tumor relapse and drug-resistance

... the potential to determine proliferation and ...increase cell cycle progression, motility, survival, and other metastatic phenotypes of tumor ...squamous cell carcinoma (HEp3) inactivates ... See full document

15

EMT and tumor metastasis

EMT and tumor metastasis

... breast cancer, CTC were found to express known EMT regulators, including TGF-β pathway components and the FOXC1 transcription ...breast cancer patients and specifically show elevated expression in patients ... See full document

13

Current status and potential challenges of mesenchymal stem cell-based therapy for malignant gliomas

Current status and potential challenges of mesenchymal stem cell-based therapy for malignant gliomas

... gastric cancer cells to promote cancer progression through a series of transformations ...neoplastic potential to contribute to mesenchymal tumour development after transducing the human ... See full document

9

Urine-derived stem cells for potential use in bladder repair

Urine-derived stem cells for potential use in bladder repair

... Stem cell-based therapy for bladder repair is most relevant to congenital bladder conditions (for example, bladder exstrophy) or conditions such as radiation damage, infec- tion, interstitial ... See full document

10

A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors

A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors

... of cancer to attempt eradication of the residual tumor ...needed. Stem cells may provide the basis for a new approach. Emerging stem cell therapy of brain tumors The lack of efficacy for ... See full document

11

Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis

Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis

... also mesenchymal cells simultaneously contribute to the initiation and development of liver diseases, although the mechanisms remain unclear ...and mesenchymal cells is important for remodeling of injured ... See full document

7

Potential clinical applications of adult human mesenchymal stem cell (Prochymal<sup>®</sup>) therapy

Potential clinical applications of adult human mesenchymal stem cell (Prochymal<sup>&reg;</sup>) therapy

... irreversible. Cell-based therapies have the potential to provide an alternative approach, according to data obtained from animal models of inflammatory nervous ... See full document

12

Development of immortalized Hertwig’s epithelial root sheath cell lines for cementum and dentin regeneration

Development of immortalized Hertwig’s epithelial root sheath cell lines for cementum and dentin regeneration

... in stem cell-based approaches of tooth tissue ...a potential source for the construc- tion of tooth ...immortalized cell lines with the characteristics of under- going EMT and ... See full document

13

Mesenchymal stem cell infusion for the treatment of neurological sequelae of canine distemper virus: a clinical study

Mesenchymal stem cell infusion for the treatment of neurological sequelae of canine distemper virus: a clinical study

... for application to patients with distemper and so the idea of using it was ...is based on the changes presented by patients at the first consultation, establishing an increasing descriptive numerical scale ... See full document

13

An improvised one-step sucrose cushion ultracentrifugation method for exosome isolation from culture supernatants of mesenchymal stem cells

An improvised one-step sucrose cushion ultracentrifugation method for exosome isolation from culture supernatants of mesenchymal stem cells

... Mesenchymal stem cells (MSCs) are multi-potent self- renewing cells having remarkable potential in regenerative ...as stem cells themselves [5, ...for cell free therapy, having low risk ... See full document

11

Mesenchymal stem cell (MSC) as a potential cell therapy for immune related disease

Mesenchymal stem cell (MSC) as a potential cell therapy for immune related disease

... its application in Inflammatory Bowel Disease (IBD) is still ...its application in each autoimmune disease as well as determining the effective dose of MSC for each type of autoimmune ... See full document

6

Role of Neonatal Dietary Ca in Bone Development and Characteristics of Porcine Mesenchymal Stem Cells.

Role of Neonatal Dietary Ca in Bone Development and Characteristics of Porcine Mesenchymal Stem Cells.

... ranked based on their expression of osteogenic and adipogenic genes under appropriate induction ...including cell adhesion, organization of the actin cytoskeleton, as well as immune-regulatory function, ... See full document

109

The challenges and promises of allogeneic mesenchymal stem cells for use as a cell-based therapy

The challenges and promises of allogeneic mesenchymal stem cells for use as a cell-based therapy

... the potential immune response? Second, what is the dynamic fate of implanted allogeneic ASCs, includ- ing being eliminated by recipients, being maintained in the stem cell state, or differentiating ... See full document

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The Osteogenic Capacity of Human Amniotic Membrane Mesenchymal Stem Cell (hAMSC) and Potential for Application in Maxillofacial Bone Reconstruction in Vitro Study

The Osteogenic Capacity of Human Amniotic Membrane Mesenchymal Stem Cell (hAMSC) and Potential for Application in Maxillofacial Bone Reconstruction in Vitro Study

... Mesencymal stem cells (MSC) are the most potential adult stem cell for bone regeneration due to their multipotential properties ...quality stem cells if taken from elderly or medically ... See full document

8

Therapeutic potential of mesenchymal stem cell based therapy for osteoarthritis

Therapeutic potential of mesenchymal stem cell based therapy for osteoarthritis

... Although MSCs have demonstrated the unique abil- ity and promise to combat degenerative diseases such as OA, they possess another mechanism of regenera- tive abilities not previously discussed: their exosomal products. ... See full document

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