[PDF] Top 20 PREPARATION AND EVALUATION OF SOLID DISPERSIONS OF OFLOXACIN

... of solid dispersion technologies to improve the dissolution characteristics of poorly water-soluble drugs and in turn their oral ...Numerous solid dispersion systems have been demonstrated in the ... See full document

... the preparation and evaluation of solid dispersions of aceclofenac with view to develop fast release formulation of ...the solid dispersions of aceclofenac by solvent evaporation ... See full document

... with ofloxacin drug nano conjugate and evaluation of control release and anti bacterial activity against clinical isolate of Pseudomonas ...for preparation of BSA nanoparticles and optimization was ... See full document

... investigation, solid dispersions were prepared and characterized to improve the solubility and dissolution of poorly water soluble drug Ketoprofen, using glucosamine HCl as a ...and solid dispersion ... See full document

... Meloxicam (Class ΙΙ drug according to Biopharmaceutical Classification System) is a highly potent non-steroidal anti-inflammatory drug of the enolic acid class of oxicam derivatives. The low solubility of Meloxicam in ... See full document

... prepared solid dispersions (SDs) of tanshinone IIA (TSIIA) with silica nanoparticles, which function as dispersing carriers, using a spray-drying method and evaluated their in vitro dissolution and in vivo ... See full document

... The drug release data obtained for formulations SD1- SD16 are tabulated in Tables 5 and 6 which represent the cumulative percent drug released as a function of time for all formulations. In vitro studies reveal that ... See full document

... Previous literature had discussed various preparations of IBU/ SDs for improving its dissolution using different carriers (Dabbagh and Taghipour, 2007; Esnaashari et al., 2005; Islam et al., 2010; Newa et al., 2007; Newa ... See full document

... as solid dispersions (SDs), lyophilization, liquisolid technique, complexation with cyclodextrin, nanosuspension and preparation of self- nanoemulsifying systems of GLB ... See full document

... release solid dispersion of Repaglinide was formulated by solvent evaporation ...Repaglinide solid dispersions were prepared using PEG 8000, Pluronic F 127 and Gelucire 44/14 by solvent evaporation ... See full document

... As soluble carrier dissolves, the insoluble drug gets exposed to aqueous environment as very fine particles and solubility gets increased. Enhancement in solubility was observed in following order. PVP K-40> PEG ... See full document

... and solid states and to improve the pharmaceutical properties of NI and ME via inclusion complexation with ...and solid state by different physicochemical ...in solid state was confirmed by ... See full document

... use solid lipid nanoparticles (SLN) to improve the pharmacological activity of ...ofloxacin. Ofloxacin-loaded SLN were prepared using palmitic acid as lipid matrix and poly vinyl alcohol (PVA) as ... See full document

... solid dispersions. In the present work an attempt was made to prepare solid dispersion (common solvent method) by using PEG 4000 and PEG 6000 in the ration of 1:1, 1:2, 1:3, 1:4, 1:9 drug polymer ... See full document

... the preparation of solid dispersion in which Nifedipine pure drug solubility was found to be ...the preparation of Nifedipine solid ... See full document

... Preliminary solubility studies were carried out to select suitable water- soluble carriers for the preparation of SD. Pure drug solubility was found to be 0.417 mg/ml. From this study, drug and Soluplus in ratio ... See full document

... by solid dispersions technique by employing L-HPC as carrier ...in solid state by Differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), Powdered X ray diffraction ... See full document

... The solid dispersion system displayed less intense and highly diffused peaks as compared to the pioglitazone ...drug-HPMC solid dispersion is ascribed to the marked reduction in the crystallinity of the ... See full document

... of solid lipid nanoparticles based gelling system of an antibiotic drug to be administered through ocular ...of solid lipid nanoparticles were prepared containing ...ofloxacin. Solid lipid ... See full document

... unprocessed candesartan cilexetil order kinetics with a very slow dissolution rate (≈1 % in 60 min). Compared to pure drug, the dissolution rate of 1:5 and 1:10 (w/w) compounds has increased significantly, reached to ... See full document