Top PDF PREVALENCE OF EXCESSIVE DAYTIME SLEEPINESS (EDS) AMONG MEDICAL STUDENTS

PREVALENCE OF EXCESSIVE DAYTIME SLEEPINESS (EDS) AMONG MEDICAL STUDENTS

PREVALENCE OF EXCESSIVE DAYTIME SLEEPINESS (EDS) AMONG MEDICAL STUDENTS

EDS is found to be associated with increased inflammatory markers such as TNF α and IL-6 [21]. If these cytokines remain chronically it will predispose an early onset of systemic disorders like Diabetes Mellitus, Hypertension etc., Also individuals with EDS were reported to have psychological problems like irritability and decreased quality of interpersonal relationships [14]. All these factors can ultimately impair the quality of life and reduce the lifespan of the affected individual. This can be prevented by early lifestyle modifications with the complete understanding and co-operation of the affected individuals
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Excessive Daytime Sleepiness and Hypertension in Cameroonian Adult Population

Excessive Daytime Sleepiness and Hypertension in Cameroonian Adult Population

Excessive daytime sleepiness (EDS) is a common clinical problem. It is one of the main consequences of sleep disorders and it is associated with a reduction of the quality of life, road accidents and workplace accidents [1, 2]. EDS is an inability to maintain vigilance and alertness during major period of the day when subject is expected to be awake, with sleep occurring unintentionally or at inappropriate times and this almost daily [3]. Its prevalence is estimated between 10 and 20% in the general population [4–12] and reaches 68% in some groups of patients [13]. The independent association between EDS and hypertension is found in several studies including patients with sleep apnea syndrome (SAS) [13–16]. Hypertension is a common condition in the general population and is one of the major risk factors for cardiovascular mortality and morbidity [17]. Studies of the relationship between EDS and hypertension in the general population regardless of association with SAS are scarce. In a prospective cohort study carried out in a relatively healthy adult population, Goldstein et al. found a high risk of developing hypertension in subjects with EDS [18]. Otherwise, in a recent prospective cohort study in Brazil, Drager et al. did not find any association between hypertension and EDS [19]. Moreover, in a group of subjects recruited from a sleep laboratory in China, normotensive subjects had a more severe SDE than hypertensive subjects with OSA [20]. The factors associated with EDS in hypertensive subjects are obesity, type 2 diabetes and uncontrolled hypertension [21]. In this light, we carried out this study having as objective to investigate the association between the EDS and hypertension, and to determine the factors associated with the EDS in the subjects having hypertension in the general adult population of Cameroon.
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Excessive daytime sleepiness is associated with an exacerbation of migraine: A population-based study

Excessive daytime sleepiness is associated with an exacerbation of migraine: A population-based study

Background: Previous studies have shown that migraine and sleep disturbances are closely associated. Excessive daytime sleepiness (EDS) is a common symptom of various types of sleep disturbance. Findings from clinic-based studies suggest that a high percentage of migraineurs experience EDS. However, the prevalence and clinical impact of EDS among migraineurs at the population level have rarely been reported. The objective of this study was to investigate the prevalence and impact of EDS among migraineurs using a population-based sample in Korea. Methods: We selected a stratified random sample of Koreans aged 19 to 69 years and evaluated them using a semi-structured interview designed to identify EDS, headache type, and the clinical characteristics of migraine. If the score on the Epworth Sleepiness Scale (ESS) was more than or equal to 11, the participant was classified as having EDS. Results: Of the 2,695 participants that completed the interview, 143 (5.3 %) and 313 (11.6 %) were classified as having migraine and EDS, respectively. The prevalence of EDS was significantly higher in participants with migraine (19.6 %) and non-migraine headache (13.4 %) compared to non-headache controls (9.4 %). Migraineurs with EDS had higher scores on the Visual Analogue Scale (VAS) for headache intensity (6.9 ± 1.8 vs. 6.0 ± 1.9, p = 0.014) and Headache Impact Test-6 (59.8 ± 10.2 vs. 52.5 ± 8.2, p < 0.001) compared to migraineurs without EDS.
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Prevalence and determinants of excessive daytime sleepiness in hypertensive patients: a cross-sectional study in Douala, Cameroon

Prevalence and determinants of excessive daytime sleepiness in hypertensive patients: a cross-sectional study in Douala, Cameroon

This study has demonstrated that a high proportion of hypertensive patients suffer from EDS. This was signi fi - cant in patients with diabetes mellitus: in snorers, in obese patients and in patients with uncontrolled BP. Patients who feel very dizzy during the day should consult their physician for screening while health per- sonnel involved in the management of hypertensive patients should screen EDS and consider weight loss in positive patients. Health-related organisations and policy- makers should promote programmes of sensitisation on EDS as well as encourage the purchase of sleep diagnos- tic tools in our context. Researchers should use this study as baseline for further studies on sleep related dis- orders in hypertensive patients in sub-Saharan Africa.
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Relationship between poor quality sleep, excessive daytime sleepiness and low academic performance in medical students

Relationship between poor quality sleep, excessive daytime sleepiness and low academic performance in medical students

Purpose: Poor quality of sleep and excessive daytime sleepiness affect cognitive ability and have a negative impact on the academic performance of medical students. This study aims to determine the prevalence of excessive daytime sleepiness, sleep quality and psychological distress as well as assess their association with low academic performance in this population. Participants and methods: A cross-sectional study was conducted among 457 medical students from the Faculty of Medicine and Pharmacy of Rabat, Morocco, who completed the Pittsburgh Sleep Quality Index (PSQI) questionnaire and the Epworth Sleepiness Scale to determine the quality of sleep and excessive daytime sleepiness, respectively. Sociodemographic variables and psychological distress (Kessler Psychological Distress Scale) were also measured. Multivariate linear regression was performed in order to evaluate the link between low academic performance and sleep quality after adjusting for other covariates.
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Factors Associated with Excessive Daytime Sleepiness in Obstructive Sleep Apnea Syndrome under CPAP Treatment

Factors Associated with Excessive Daytime Sleepiness in Obstructive Sleep Apnea Syndrome under CPAP Treatment

In PSQI-J component scores in the present study, overall sleep quality (C1), duration of sleep (C3), sleep disturbance (C5), and day dysfunction due to sleepiness (C7) were significantly higher in the EDS(+) group than in the EDS(–) group. It was obvious that day dysfunction due to sleepiness (C7) were more severe in the patients with EDS compared to those without EDS. It was sug- gested that EDS was associated with low subjective sleep quality, short sleep duration and more sleep disturbed in the patients of EDS(+) group. EDS in OSAS is not al- ways caused by sleep apnea alone, although causative relations should further be evaluated. It should be pointed out that sleepiness is a common symptom in the general population, and often results from sleep deprivation. This type of sleepiness will not improve with CPAP if they do not have sleep disorders breathing. EDS in OSAS under good CPAP compliance may be caused clinically, by 1) development of new conditions associated with OSAS/ CPAP, such as increase in weight, rhinitis or other medical illness; or 2) an undiagnosed associated condition such as poor sleep hygiene, treatment with sedating drugs, de- pression, or other sleep disorders; or 3) loss of placebo (honeymoon) effect revealing the conditions not previ- ously diagnosed [10]. It was suggested that the subjective sleep evaluation, chiefly EDS, in the OSAS patients under CPAP treatment may have involved many factors sur- rounding the sleep habits, chiefly behaviorally induced insufficient sleep.
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Factors associated with diabetes-related distress over time among patients with T2DM in a tertiary hospital in Singapore

Factors associated with diabetes-related distress over time among patients with T2DM in a tertiary hospital in Singapore

BMI: Body mass index; DRD: Diabetes-related distress; EDS: Excessive daytime sleepiness; EMR: Electronic medical records; GEE: Generalized estimating equation; GLM: Generalized linear model; HbA1c: Glycated haemoglobin; HRQoL: Health-related quality of life; OSA: Obstructive sleep apnea; PAID: Problem areas in diabetes; PUBMED: Search engine accessing primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics; RLS: Restless leg syndrome; T2DM: Type 2 diabetes mellitus

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Excessive daytime sleepiness and adherence to antihypertensive medications among Blacks: analysis of the counseling African Americans to control hypertension (CAATCH) trial

Excessive daytime sleepiness and adherence to antihypertensive medications among Blacks: analysis of the counseling African Americans to control hypertension (CAATCH) trial

We used frequency distribution and measures of central ten- dency to describe sociodemographic factors and the overall health risk profile of the sample. We used multiple logistic regression analysis to assess for an association between EDS and medication adherence, adjusting for effects of age, sex, employment, education, body mass index, and smoking and drinking history. All analyses were conducted using Statis- tical Package for the Social Sciences version 20 software (SPSS Inc., Armonk, NY, USA). All participants provided written consent and the study was approved by the New York University Medical Center Institutional Review Board.
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Association of excessive daytime sleepiness with migraine and headache frequency in the general population

Association of excessive daytime sleepiness with migraine and headache frequency in the general population

Another potential limitation is that the data reported in the present study were self-reported. This study asked about lifetime prevalence of migraine. The single ques- tion about lifetime occurrence of migraine, which was used, has previously been evaluated against a clinical interview by two physicians in another Norwegian sur- vey in eastern Akershus County, reporting a raw agree- ment rate of 0.81 and kappa (κ) of 0.62, which is considered to be a good agreement [23]. Two previous epidemiological surveys used the same screening ques- tion for migraine as in the present study, and the ob- served agreement rates were 0.92 and 0.94, and κ were 0.77 and 0.81, respectively [2, 40]. Due to the high num- ber of participants in our survey, it was not feasible to apply the gold standard, i.e. a clinical interview by a physician/neurologist with expertise in headache diag- nostics. The current study did not investigate the effect of EDS on clinical characteristics of migraine, which would require more detailed clinical information than is possible in a questionnaire-based general population survey.
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Excessive daytime sleepiness in secondary chronic headache from the general population

Excessive daytime sleepiness in secondary chronic headache from the general population

headaches are poorly understood, thus, further research is warranted [23]. Studies suggest that CEH can be explained by local factors in the neck with dysfunction of the neck muscles and mechanical cervical spine pathology leading to limited cervical movements and projection of the pain [24]. Headaches attributed to head trauma and whiplash trauma have instead been sug- gested to represent an interplay between the physical in- jury, neuroinflammation, psychological disturbances and emotional stress of the accident [25, 26]. Finally, long- standing oedema of the nasal mucosa and rhinosinal in- flammation result in chronic rhinosinusitis which may give chronic headache [12]. The present study reported that CPTH/CEH and HACRS had similar prevalence of EDS despite these different headache forms probably be- ing caused by different pathophysiological mechanisms. Therefore, it may be the complex burden of pain, more than the specific condition that is associated with EDS. Furthermore, the prevalence was comparable to that of two other different headache entities; chronic migraine and chronic tension-type headache [11].
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Risk of obstructive sleep apnea and excessive daytime sleepiness in hospitalized psychiatric patients

Risk of obstructive sleep apnea and excessive daytime sleepiness in hospitalized psychiatric patients

reporting by our participants of their EDS. Despite most patients in this study sleeping less than 7 to 8 hours per day, there was no significant association between reported sleep time and EDS. A possible explanation for this finding may be habituation to chronic EDS in this patient population. Objec- tive measures of EDS, such as polysomnography with mean sleep latency testing, would be able to further quantify daytime sleepiness in this patient population. The relatively lower prevalence of EDS could also potentially be attributed to posi- tive behavioral changes, and improved sleep hygiene that the participants are exposed to during their stay at the psychiatric unit. Switching or adjusting the patients’ psychotropic medica- tions during hospitalization might also have contributed to the lower prevalence of EDS in this sample. In a previous study, patients with substance abuse were found to be at a very high risk of experiencing sleep disorders. 40 Even though EDS in
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Prevalence and Assessment of Excessive Daytime Sleepiness in Diabetic and Obese Patients.

Prevalence and Assessment of Excessive Daytime Sleepiness in Diabetic and Obese Patients.

E. O. Bixler et al., in their study indicated that when diagnosing a case with a complaint of EDS, sleep disturbance (e.g. due to sleep apnea) should not be considered the only cause. It appears that EDS is more strongly associated with mood factors (e.g. depression) as well as metabolic factors (obesity and/or diabetes), i.e. the metabolic syndrome. EDS appears to be more prevalent in the very young, suggesting unmet sleep needs and/or depression. EDS is also more prevalent in the very old, most likely associated with increasing medical illnesses and health issues. Their findings indicated that patients with a complaint of EDS should be adequately assessed for depression, obesity, and/or diabetes both in the presence or absence of sleep apnea and then treated appropriately. 40
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Factors Associated with Smoking Behaviors among Military Cadets of King Khalid Military Academy (KKMA), Riyadh, Saudi Arabia (2015-2016)

Factors Associated with Smoking Behaviors among Military Cadets of King Khalid Military Academy (KKMA), Riyadh, Saudi Arabia (2015-2016)

The present study showed that the excessive daytime sleepiness was prevalent among the medical students, The University of Tabuk, no significant statistical differences was found between the students with the excessive daytime sleepiness and others without this serious sleep disorder regarding age, sex, hours spent in Technology/day, coffee intake, use of sleep medications, and chronic diseases. The current data showed that the use of Technology was higher among those with excessive daytime sleepiness. It is a well-established fact that attentiveness during class time is a significant determinant of academic achievement; excessive daytime sleepiness could lead to fatigue and substantially impair attention. 6 The situation of excessive daytime
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<p>The Effect of Sleep Quality on Students&rsquo; Academic Achievement</p>

<p>The Effect of Sleep Quality on Students&rsquo; Academic Achievement</p>

Sleep is an inseparable part of human health and life, and is pivotal to learning and practice as well as physical and mental health. 1 Studies have suggested that insuf fi cient sleep, increased frequency of short-term sleep, and going to sleep late and getting up early affect the learning capacity, academic performance, and neurobehavioral functions. 2,3 Previous studies have indicated that the quantity of sleep reported by individuals as delayed or inappropriate sleep, waking up too late, especially at weekends and daytime sleepiness is associated with compromised academic performance in children and adults. 2 Some studies have emphasized the relationship between delayed starting time of classes and academic success. 4 Reduced overnight sleep or altered sleep patterns has been associated with severe drowsiness and failure in academic success. 5 In a study, people who had enough sleep compared to their sleep-deprived individuals used innovative solutions twice as often when confronted with complex mathematical problems. 6 The chance of academic failure was as long as one or more than 1 year in students with inadequate sleep compared to those with proper sleep. 7 People who sleep less and sleep during the day are more prone to vehicle and work accidents. 8 In some studies, sleep ef fi ciency has been considered as essential for recovery, cognitive processing, and memory integration. 9 On the other hand, lack of sleep has been associated with
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Daytime Sleepiness and Hyperactivity in Children With Suspected Sleep-Disordered Breathing

Daytime Sleepiness and Hyperactivity in Children With Suspected Sleep-Disordered Breathing

rameters and daytime sleepiness in this study brings up the possibility either that we are not measuring the right parameter during routine PSG or that the commonly measured parameters in PSG are not sen- sitive determinants of daytime sleepiness. Sleep frag- mentation seems not to be a major factor in the development of daytime sleepiness in children with OSAS, as there was no significant correlation be- tween daytime sleepiness and the arousal index. In fact, previous studies have shown that apneas in children are terminated by arousal less often than in adults, leading to less fragmented sleep. 36 Theoreti-
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Obesity and Excessive Daytime Sleepiness in Prepubertal Children With Obstructive Sleep Apnea

Obesity and Excessive Daytime Sleepiness in Prepubertal Children With Obstructive Sleep Apnea

In this study, we show that prepubertal obese snoring children are at greater risk for developing EDS (objec- tively assessed with a multiple sleep latency test), com- pared with nonobese children with OSA of similar se- verity. Our findings not only confirm our previous report on the association between polysomnographic measures of respiratory disturbance and the magnitude of EDS 21 but also support the concept that, although

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Prader Willi syndrome, excessive daytime sleepiness, and narcoleptic symptoms: a case report

Prader Willi syndrome, excessive daytime sleepiness, and narcoleptic symptoms: a case report

Modafinil is a psychostimulant prescribed for the treatment of sleepiness in narcolepsy and other hyper- somnia disorders. The mechanism or set of mechanisms through which modafinil promotes arousal and activity are incompletely understood; however, it is believed to activate the catecholamine systems at α and β adrenergic receptors and dopamine receptors [10]. Treatment with modafinil in small pilot studies has been shown to im- prove the sleepiness in patients with PWS [11] and was clinically beneficial for our patient. The drug, however, has no reported benefit on control of cataplexy [12]. Our patient began treatment with modafinil at age seven years six months of age (initially at 50mg daily and then progressed to 150mg daily). Two PSGs were performed subsequent to the initiation of this drug and both re- vealed an improvement in a number of sleep parameters. The PSG performed at ages eight and nine demonstrated excellent improved sleep efficiencies of 94 and 95 per- cent, respectively. Additionally, modafinil therapy in our patient eliminated SOREM periods and decreased REM sleep latency. However, a reduction in REM sleep remained at the final PSG at eight years of age, indicating that not all aspects of sleep abnormality were ameliorated with modafinil treatment. It is worth noting that at the increased modafinil dosage (150mg daily), a longer period of REM sleep was observed. Therefore, further optimization of modafinil dosing might be helpful. A MSLT would have been useful in objectively assessing the impact of modafinil on our patient’s hypersomnia after a period of therapy; how- ever, the patient refused further MSLT testing. A significant improvement in alertness, irritability, and reduction in naps and cataplectic episodes was noted by caregivers.
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The Psychosocial Problems of Children With Narcolepsy and Those With Excessive Daytime Sleepiness of Uncertain Origin

The Psychosocial Problems of Children With Narcolepsy and Those With Excessive Daytime Sleepiness of Uncertain Origin

We are most grateful to the children and their parents who contributed to the study and to those who helped with recruitment. We are especially indebted to the fol- lowing colleagues who provided participants and ar- ranged for assessments to be made outside the United Kingdom: Dr Marie-Josephe Challamel (Centre Hopi- talier Lyon-Sud, Pierre-Benite, France); Dr Helena Es- tevao (Hospital Pediatrico de Coimbra, Coimbra, Portu- gal); Dr David Gozal (University of Louisville, Louisville, KY); Dr Carole Marcus (Johns Hopkins University, Bal- timore, MD); Prof Sona Nevsimalova (Charles Univer- sity, Prague, Czech Republic); Dr Stephen Sheldon (Chil- dren’s Memorial Hospital, Chicago, IL); Dr Michael Thorpy (Montefiore Medical Centre, New York, NY); and Dr Margot Davey (Monash Medical Centre, Mel- bourne, Australia).
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Neuropsychiatric Complications of Patients with Obstructive Sleep Apnea Syndrome

Neuropsychiatric Complications of Patients with Obstructive Sleep Apnea Syndrome

Inclusion criteria for the study were: 1) Egyptian ethnicity; 2) patients who had been referred for snoring, fatigue, and/or daytime sleepiness and diagnosed as OSA with AHI > 5 and admitted to intensive care units. 3) Ability to give written consent or the availability of patients' guardians to give consent to participate in this study; and 4) ability to have informed knowledge of the patients’ earlier and current cognitive functioning. Exclusion criteria included: 1) Previous treatment for sleep apnea with CPAP, corrective airway surgery or a mandibular advancement device; 2) refusal to perform maintenance wakefulness test; 3) the presence of cardiovascular risk factors (hypertension, diabetes, dyslipidaemia ---etc ,and 4) presence of a mental, neurological or physical impairment severe enough to participate and complete the questionnaires.
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Clinical Assessment Of Non Motor Symptoms In Parkinson’s Disease

Clinical Assessment Of Non Motor Symptoms In Parkinson’s Disease

study by Paus et al. (2003) where there was 75% incidence of excessive daytime sleepiness using ESS Score (≥ 10).In the present study we observed that 21.33% (n=32) patients had restless leg syndrome (RLS). Out of these, all the patients belonged to mild (n=24, 16%) and moderate (n=8, 5.3%) severity of RLS score. Also we have observed that 40.67% (n=61) patients had RBD problems (RBD Scale >5). The mean RBD Score was statistically significant between the treated and drug naïve PD (4.10 ± 3.39 vs 1.60 ± 2.40). It was also observed that as the disease progresses there was increase in the severity of RBD symptoms. We also observed that there is an increased occurrence of hallucinations (n=40, 65.57%) in PD patients with RBD and all the patients had poor overall sleep quality. This study was similar to the study by Madhuri Behari et al. (2013) observed higher frequency of hallucinations among RBD patients. Kee Hyung Park et al. (2016) observed that RBD patients had more sleep disturbances, lower sleep quality and more motor disability.
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