Top PDF The Prevalence of HCV, HBV, HIV in Blood Donors of Golestan Province, (2006-2008)

The Prevalence of HCV, HBV, HIV in Blood Donors of Golestan Province, (2006-2008)

The Prevalence of HCV, HBV, HIV in Blood Donors of Golestan Province, (2006-2008)

9_ Uneke CJ, Ogbu O, Lnyama P, Anyanwa GL, Njoku MO, Iobok IH, Prevalence Of hepatitis-B Surface antigen among blood donors and human immunodeficiency Virus- infected Patients in jos,Nigeria .Men inst oswaldo cruz,Riode Janeiro , 2005;100(1):13_16.

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Objective: To assess the prevalence of HBV,HCV and HIV among replacement donors and voluntary

Objective: To assess the prevalence of HBV,HCV and HIV among replacement donors and voluntary

Blood transfusion is a significant route of transmission of infectious diseases like HBV, HCV and HIV. These diseases are of great concern because they can cause fatal acute and chronic life threatening disorders, risks may be reduced by the vigorous screening of donors and donated blood. Prevalence of HBV, HCV and HIV among the healthy blood donors or the replacement donors reflect the disease prevalence in the community 7 . Due to limitation in current blood screening practices in developing countries, donation by such individual is a potential threat to recipient 8 .
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Prevalence of HBV and HCV among blood donors in Kosovo

Prevalence of HBV and HCV among blood donors in Kosovo

Out of 70348 samples of the blood donors, 3145 were positive. From overall positive samples, 2939 were HBV positive, 192 HCV positive while 14 samples were positive for both viruses. The HBV prevalence among the blood donors of Kosovo is 4.2%, which range Kosovo to the second zone according to the CDC classification of the geographical spread of the HBV infection. The HCV prevalence among the blood donors in Kosovo is 0.3%. Compared to the other European countries this level of prevalence is relatively low.
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Systematic review and meta analysis of HIV, HBV and HCV infection prevalence in Sudan

Systematic review and meta analysis of HIV, HBV and HCV infection prevalence in Sudan

systematic review was aimed to provide pooled seroprevalence estimates of the three viruses in Sudan. Structured review of the literature was conducted to obtain relevant studies published in both national and international databases. After assessment of quality and bias in all proposed studies, 57 prevalence studies were included. Meta-analysis was conducted for all studies and subgroup analysis was also approached. The total sample size of participants in included studies providing HIV antibodies prevalence was 15,479. Based on information retrieved from these studies, HIV prevalence ranged from 0 to 18.3% among different study populations. However, pooled prevalence estimate for HIV antibodies was 1%. Kassala, Eastern Sudan was the most endemic State (4.18%). The HBV reported seroprevalence rates ranged from 5.1 up to 26.81% among different populations and the overall pooled prevalence was 12.07%. For HCV antibodies; 2.74% was determined to be the pooled prevalence. Khartoum State was the most endemic State of both HBV and HCV with seroprevalence of 12.69% and 6.78%, respectively. Based on data reviewed and synthesized; there is no evidence for an HIV endemic in the general population of Sudan. However, both HBV and HCV seroprevalence rates are indicating otherwise. Reducing the overall burden of HIV, HBV and HCV infections will require new measures and national strategies and the recognition of the infections as one of the country ’ s priority issues.
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Prevalence of HBV and HCV Infections among Blood Donors in Northeast Libya

Prevalence of HBV and HCV Infections among Blood Donors in Northeast Libya

The prevalence of hepatitis infection in the general population in Northeast of Libya is not available due to the lack of publication for the past decades. Hepatitis markers are important tests in screening blood donors and prevent transfusion-related hepatitis. Total 78.987 donors were screened over an 8-year period from 2008 to 2015. The results of this study indicate that of the apparently healthy voluntary blood donors in four regions (172) 0.21% were positive for HBsAg and (197) 0.24% were positive for anti- HCV (total number 369). This prevalence for HBsAg is lower than that reported in the international finding in Libya during 2003 (2.2% for HBV and 1.2% for HCV) [8]. In Libya, a study conducted between 1991 and 2001 indicated that the prevalence of HCV infection ranged from 1.2% to 1.6% among blood donors, similar to the prevalence among the general population reported in 2014 of 1.2%, though it was much higher (20.5%) among hospital personnel but similar to that reported from the western region 0.8% for HBV and 0.7% for HCV [11]. This could be explained by the fact that families of blood receipts search for “physically healthy” blood donors. The prevalence of HBsAg among blood donors has been found to be 9.8% in Yemen [12], 1.2% in Egypt [13] and 1.2–1.7% in India [14].
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Seroprevalence and risk factors for HIV, HCV, HBV and syphilis among blood donors in Mali

Seroprevalence and risk factors for HIV, HCV, HBV and syphilis among blood donors in Mali

Continuous variables were described with median and interquartile range [IQR] and categorical variables as number and percentages. The prevalence of HIV, HBV and HCV was expressed with a 95% confidence interval (CI95%) and group’s comparison was performed using Chi-2 test for categorical variables. Univariable and mul- tivariable (including gender, age, education level (none, primary school, secondary school, higher), marital status, geographical setting and type of blood donation covari- ates) logistic regression analyses were performed with R (v3.6.1) [11] software to identify risk factors of each in- fection. Factors associated with HIV, HBV or HCV in- fection with a P value of < 0.20 in the univariate logistic regression analyses were included in the multiple logistic regression model. The level of significance for each ana- lysis was set at 0.05.
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Seroprevalence of transfusion transmissible viral infections (HIV, HBV and HCV) among voluntary blood donors at University of Gondar Comprehensive Specialized Hospital, Gondar; Northwest Ethiopia

Seroprevalence of transfusion transmissible viral infections (HIV, HBV and HCV) among voluntary blood donors at University of Gondar Comprehensive Specialized Hospital, Gondar; Northwest Ethiopia

Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) are the greatest threats to blood safety because of their prolonged pres- ence in the blood as a carrier or latent state. They are the leading cause of death, chronic and life-threatening abnormality. Blood transfusion accounts for 5–10% of HIV infections in sub-Saharan Africa [1]. The frequency of HIV infection among blood donors varies significantly between different countries of the world. There is a strong association between infection with the human immunodeficiency virus and hepatitis C virus infection [2]. HIV infection occurs worldwide and is endemic in central Africa. Transmission occurs through sexual con- tact, exposure to contaminated blood or blood products, and perennially. Human immunodeficiency virus is one member of the human retrovirus and is associated with progressive immune deficiency accompanied by a wide range of opportunistic infections [3].
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Trace Element Levels, Cytokine Profile and Immune Activation Status in Plasma among Repeat Blood Donors with Asymptomatic HIV 1, HBV and HCV Infection

Trace Element Levels, Cytokine Profile and Immune Activation Status in Plasma among Repeat Blood Donors with Asymptomatic HIV 1, HBV and HCV Infection

The project was approved by institutional review board including ethical clear- ance. The donors were explained the purpose of the study. Written consent for the study was obtained from the donors using a predesigned consent form in lo- cal language. During the period from July to December 2016, all the major blood banks including the private ones in the national capital territory of Delhi were requested to refer the blood donors found seropositive for HIV, HBV and HCV at their centres to the Centre for AIDS and Related Diseases, National Centre for Disease Control (NCDC). A total of 120 blood donors (all males), 40 each con- firmed to be seropositive for HIV-1, HBV and HCV at NCDC were selected for the study. The period between detection of seropositivity for HIV-1, HBV and HCV in the blood banks referring the donors and confirmation of the same at Centre for AIDS and Related Diseases department, NCDC was considered dura- tion of infection since diagnosis. In addition, since the donors were repeat do- nors donating blood at intervals of 4 - 8 months, whenever a seropositive blood donor was referred by a blood bank to our centre, test results for HIV, HBV and HCV at preceding blood bank attended by the seropositive donors were checked from the records available with blood banks to confirm seronegativity at the time of preceding donation. Forty, age and socioeconomically matched male blood donors seronegative for HIV-1, HBV and HCV infections and donating at the same blood banks were included as controls.
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Prevalence of anelloviruses (TTV, TTMDV, and TTMV) in healthy blood donors and in patients infected with HBV or HCV in Qatar

Prevalence of anelloviruses (TTV, TTMDV, and TTMV) in healthy blood donors and in patients infected with HBV or HCV in Qatar

The current study was conducted on a total of 607 blood samples from healthy blood donors ( n = 500), sub- jects with HBV ( n = 54) or HBC ( n = 53). Findings of the present study showed an overall high prevalence rates of the three viruses (Fig. 1); TTV prevalence rates (85.2%t) were significantly higher ( p < 0.05) than the other two vi- ruses (76.3 and 66.6% for TTMDV, and TTMV, respect- ively). A closer comparative look at the ditribution of the three viruses in the different study groups (healthy, HBV, and HCV) revealed interesting findings. Firstly, the incidences of the three viruses were significantly high in the HBV and HCV groups as compared to the healthy group ( p < 0.05) (Table 2); prevalence rates were even highre in the HBV group (reaching 98% in the HBV group for TTMDV). Secondly, the prevalence rates of the three viruses were significantly different in the healthy ( p < 0.001) and HBV ( p < 0.04) groups but not in the HCV group (Table 2).
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HIV, HBV, HCV and T. palliduminfections among blood donors and Transfusion-related complications among recipients at the Laquintinie hospital in Douala, Cameroon

HIV, HBV, HCV and T. palliduminfections among blood donors and Transfusion-related complications among recipients at the Laquintinie hospital in Douala, Cameroon

Blood transfusion therapy is used among patients with se- vere anemia due to various medical, surgical or obstetric conditions, and in patients undergoing transplantation of an organ. Blood transfusion is beneficial and safe for the recipient when it is performed in strict compliance with immunological and hygienic standards, and following a strict screening of donors. In Cameroon, the current blood safety guidelines necessitate blood banks to routinely per- form serological testing for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and Treponema pallidum ( T. pallidum ). These guidelines progressively followed the exponential rise in blood donors from 75,000 in 1992 to 130,000 in 2002 [1], however, necessitate regular monitoring and adaptation to frequently changing epidemiological and demographic pa- rameters that include urbanization, migration flows, and increased demand for blood transfusion in the country. Although blood safety has greatly improved over the past 15 years, TTIs still represent a major public health pro- blem in Cameroon given the high prevalence of HIV infections, hepatitis, malaria, and several sexually trans- missible diseases (STD) [2,3]. Data recorded in 2006 show that 26,079 units of blood were collected in health faci- lities in Cameroon with over 2,477 infected cases, thus a TTIs prevalence of 9.5% among blood donors. Of these in- fectious risks, viral infections (HIV, HBV and HCV) are the most feared by patients and prescribers [4-7]. In Cameroon, screening for hepatitis B and C virus was not part of routine tests performed in blood donors until the year 2005. The reduction of the residual risk of contami- nation is currently based on a strict selection of donors and the introduction of new tests such as genomic testing for HIV, HCV and HBV [6,8]. A study conducted among blood donors at the Yaoundé Central Hospital (YCH) re- vealed that the risk of TTI from patients with residual in- fections remains high (9.8%) in Cameroon [9]. Bacterial contamination remains a major risk of infection during blood transfusions. Endotoxic shock caused by massive, usually Gram-negative, bacterial contamination is rare but represent a very serious outcome that includes sudden death [10]. Bacterial infections including T. pallidum have been reported in Cameroon, and are common in many other countries [11-14].
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Prevalence of HIV, HCV, HBV in Blood Donors of Golestan Province, Iran, 2012 - 2013

Prevalence of HIV, HCV, HBV in Blood Donors of Golestan Province, Iran, 2012 - 2013

Results: The blood donors were 47,830 and 45,811 in 2012 and 2013, respectively. The Prevalence of HBV in 2012 was%0. 299 and in 2013 %0. 284; of HCV % 0. 06 in 2012 and % 0.05 in 2013, and the prevalence of both HCV and HIV totally was 0. 001percent in two years of study. The highest rate of positive case was among the first time donors, married and in those with less than high school education (P<0.05).

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Blood Donors Status of HIV, HBV and HCV in Central Blood Bank in Tripoli, Libya

Blood Donors Status of HIV, HBV and HCV in Central Blood Bank in Tripoli, Libya

A national serological survey for HBV and HCV infections among the general population was performed in Libya during 2003 and revealed prevalences of 2.2% and 1.2% for HBV and HCV, respectively [8]. Other local surveys reported that the rate of HBsAg positivity among blood donors ranged from 1.3% to 4.6% [9], while the rate of HCV antibodies was 1.2% [10]. The present study has been conducted to screen the HIV, HBV and HCV in blood donors in western Libya (Tripoli area), as well as to estimate the correlation risk factors in blood donor samples. This would be an important factor for the health authorities to consider in blood donor bank.
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Article: Prevalence and risk factors of Human Immunodeficiency virus, Hepatitis B virus, Hepatitis C virus and Syphilis infections among nonprofessional blood donors in Chittagong, Bangladesh

Article: Prevalence and risk factors of Human Immunodeficiency virus, Hepatitis B virus, Hepatitis C virus and Syphilis infections among nonprofessional blood donors in Chittagong, Bangladesh

We know that Hepatitis B virus is transmitted by blood, sexual contact, by birth, contact to body fluid etc. While our study, after getting any positive donor, we tried to find out by questionnaire what factors are contributed to transmit viruses (Table 4). In our questionnaire, 71.43% HBsAg positive donors was not aware of what factors are responsible for the transmission of Hepatitis B virus; 21.43% positive donors had sexual relationship to the commercial sex workers or extra married sex partners, Even 7.14% positive donors informed about their parents that they (either father or mother or both) were carrier of Hepatitis B virus. In similar questionnaire about the HCV study, 50% HCV positive donors was not aware of what factors are responsible for the transmission of Hepatitis C virus; 50% positive donors informed that they taken intravenous drug. In our study 71.43% HBsAg and 50% HCV positive donor did not know about the route of HBsAg and HCV transmission, which indicated that the blood donors are unconscious and illiterate. So we can suggest that government and non-government organization taken special attention for HBV, HCV infection by blood donation.
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Prevalence of Occult Hepatitis B Infection among HBsAg Negative Blood Donors in Golestan Province

Prevalence of Occult Hepatitis B Infection among HBsAg Negative Blood Donors in Golestan Province

region. In another study in southeastern part of Iran (Sistan and Baluchestan province), which is a high HBsAg prevalence area, HBV-DNA positive was observed in neither the HBsAg- negative nor anti-HBc-positive donors. Furthermore, the broad range of OBI (0.006%- 22%) has been reported among blood donors in different parts of the world. For instance, in European countries like Poland, Italy, Spain, and Germany, OBI pervasiveness rates of 0.006%, 0.22%, 0.05%, and 0.0006%, have been reported respectively. All in all, these data imply that the prevalence of OBI is distinctive in every country [11].
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Trends of Transfusion Transmissible Infections among the blood donors In a Tertiary Care Hospital

Trends of Transfusion Transmissible Infections among the blood donors In a Tertiary Care Hospital

test tube. Five mandatory TTI s for which screening was done in the Blood Bank immediately after collection are Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV), Hepatitis C Virus (HCV), Malaria & Syphilis. To detect TTI in the collected blood following tests are being conducted in the institution. The screening of HIV is done by ELISA using Erba Lisa [TRANSASIA BIO- MEDICALS LTD] kit. The screening of HBsAg for HBV is done by ELISA using Erba Lisa [TRANSASIA BIO-MEDICALS LTD] kit. (HCV) infection was screened for anti-HCV by ELISA using Erba Lisa [TRANSASIA BIO-MEDICALS LTD] kit. Test for Syphilis is done by R.P.R. Test kit supplied by NACO. Malaria parasite was tested by ICT using My test [NanoEnTek] Kit. All the tests were performed according to the manufacturer’s instructions. The samples which came reactive were again repeat tested on the following day to confirm them positive. The blood bag was discarded for which the pilot sample was positive and corresponding donor was notified.
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Seroprevalence of transfusion transmitted infection among blood donors at Jijiga blood bank, Eastern Ethiopia: retrospective 4 years study

Seroprevalence of transfusion transmitted infection among blood donors at Jijiga blood bank, Eastern Ethiopia: retrospective 4 years study

Out of 4224 blood units collected, 487 units that tested positive for any of the TTI tested giving an overall posi- tivity rate 11.5  %. No co-infection reported during this study period. Of all the TTI, hepatitis B form major- ity of infection 460/4224 (10.9 %), followed by hepatitis C 17 (0.4  %), while the least percentage was HIV and syphilis 6 (0.1  %), 4 (0.1  %) respectively. High percent- age of TTI was reported in 2010 (14.1  %), followed by 2012 (12.4 %), while least was reported on 2011 (10.1 %). High percentage (13.9 %) of HBV was reported in 2010, followed by 2012 (11.6  %), the least was reported in 2011 (9.4  %). There was statistically significant (Chi square  = 9.24 P value  = 0.02) change in sero-positivity from year 2010 to 2013. Trends of Hepatitis B also statis- tically significant from year to year (Chi square = 11.14 P value = 0.01). All TTIs types were reported in 2011 and 2013, while syphilis cases were not reported in 2010 and 2012 (Table 2). When grouping (HCV, HIV, and syphilis) by years, the percentage was increasing from year 2010 (0.3 %), 2011 (0.6 %), 2011 (0.8 %), and decline in 2013 (0.7 %), but there was no statistically significant change (P value = 0.576) (Table 2).
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HIV, HBsAg and HCV prevalences among voluntary blood donors in Mumbai: trends over a decade

HIV, HBsAg and HCV prevalences among voluntary blood donors in Mumbai: trends over a decade

Background: With over 93 million donations made every year worldwide, blood transfusion continues to save millions of lives each year and improve the life expectancy and quality of life of patients suffering from life threatening conditions. At the same time, blood transfusion is an important mode of transmission of infection to the recipient. The present study was conducted to estimate the prevalence of HIV, HBV and HCV infections in voluntary blood donors at a tertiary care teaching hospital in Mumbai over a decade.
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Abstract Aims & Objectives: Effective screening of donors blood as per WHO guidelines and to assess the sero

Abstract Aims & Objectives: Effective screening of donors blood as per WHO guidelines and to assess the sero

Efavirenz drugs are of immense value in controlling HIV viral replication. Entecavir & Telbivudine achieve HBV – DNA negativity in 90% of patients at one year of treatment of HBV. Graphs shown below clearly indicate the seroconversion of HBV and the carrier state and the next graph depicts seroconversion of HIV which are helpful in planning the drug treatment and resistance. Nucleic acid based assays of latest generation based on molecular biology of HIV, HBsAg, HCV are of great value in detecting even the lowest viremia even during window/latent phase of seroconversion. As such genetic based gadgets are used in the west the TTi prevalence rate is the lowest in the world. Only snag with such gadgets is they are not cost effective for developing countries with population explosion. The molecular structure of Hepatitis ‘B’ virus which is useful in targeting the drug action. HBV mutation and the natural course of Hepatitis ‘B’ disease with different phases of seroconversion like tolerance, clearance, latency and mutation which are significant in planning the time of performing the screening and diagnostic test to minimise TTi. Whereas Graph 1 gives a telltale picture of the amplitude of titre of different HBV antibodies which are of immense value in controlling the disease and minimising the spread of it. Graph 2 about the biological behaviour of HIV gives an idea about the seroconversion that takes place during the first few weeks of the total progression of the disease from 4 weeks to 3 years. The full blown picture of AIDS disease develops at the other end of the time scale of HIV. During the course the CD 4 titre falls after initial rise with the viral load (VL) increasing with advancing time. Untreated HIV cases can progress to AIDS in 25 – 35 % of patients.
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Investigation of Hepatitis Functioning through Bilurbin at Blood Donors with HBV and HCV Positive

Investigation of Hepatitis Functioning through Bilurbin at Blood Donors with HBV and HCV Positive

[9] Elzouki, A.N., Smeo, M.N., Sammud, M., Elahmer, O., Daw, M., Furarah, A., Ab- udher, A. and Mohamed, M.K. (2013) Prevalence of Hepatitis B and C Virus Infec- tions and Associated Risk Factors in Libya: National Sero-Epidemiological Survey. The Eastern Mediterranean Health Journal , 19, 589-599.

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Seroprevalence of markers of transfusion transmissible infections among blood donors at a tertiary care hospital blood bank: a 5 year retrospective study

Seroprevalence of markers of transfusion transmissible infections among blood donors at a tertiary care hospital blood bank: a 5 year retrospective study

Background: Transfusion transmitted infections (TTIs) can be caused by various microorganisms present in the blood of apparently healthy donors. The recipient may get infected after being transfused with the unsafe blood. It is mandatory to screen the blood for HIV 1 and 2, HBV, HCV, Syphilis and Malaria. This study was undertaken to investigate the seroprevalance of Transfusion transmitted infections among blood donors at our tertiary care centre and to compare our study with other studies conducted at different hospitals of the country as well as outside.
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