[PDF] Top 20 Primordial germ cells: the first cell lineage or the last cells standing?
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Primordial germ cells: the first cell lineage or the last cells standing?
... that cell-intrinsic events governing the specification of human PGCs are also different from those in mice, at least based on the results of in vitro ...PGC-like cells derived from human embryonic stem ... See full document
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Deadenylase depletion protects inherited mRNAs in primordial germ cells
... all cells reduces the enrichment of Seawi transcript in the sMics, detected by FISH (green), compared with mCherry alone ...sMic lineage is traced by EdU incorporation ...EdU-positive cells in ... See full document
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The migrations of Drosophila muscle founders and primordial germ cells are interdependent
... the germ cells, we disabled Wunen function in the PGCs using tissue-specific RNAi- mediated knockdown of wun or ...important. First, wun2 transcripts are detectable within germ cells ... See full document
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Closing the circle of germline and stem cells: the Primordial Stem Cell hypothesis
... At first sight, it seems counter-intuitive, due to the fact that asexually re- producing animals have been traditionally understudied, and the germline concept has only been associated with sexual ...the ... See full document
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Germes is involved in translocation of germ plasm during development of Xenopus primordial germ cells
... plasm’. Germ plasm is present in the vegetal cortex of a fertilized egg, where it divides into about four blastomeres via the first two cleavages, and then distributes unequally to daughter cells ... See full document
6
Mouse primordial germ cells produce cysts that partially fragment prior to meiosis
... of primordial follicles ...original cell. The oocyte normally forms from the most downstream cell, which is the initial cell in 16-cell Drosophila ...one cell that is still ... See full document
7
The allocation and differentiation of mouse primordial germ cells
... the lineage potency of epiblast cells of the early-streak stage mouse embryo reveals that the developmental fate of the cells is determined by their position in the germ ...Epiblast ... See full document
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Transient translational quiescence in primordial germ cells
... stem cells (Rezza et ...stem cells are also common in cancer and are the bane of chemotherapy; a quiescent cancer stem cell escapes many of the cancer treatments intending to kill the rapidly ... See full document
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The distribution and behavior of extragonadal primordial germ cells in Bax mutant mice suggest a novel origin for sacrococcygeal germ cell tumors
... the first postnatal week. Heterozygous Bax littermates had fewer midline germ cells at ...in germ cells when they reach the genital ridges, and remains on throughout embryogenesis and ... See full document
12
Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells
... embryonic cells and for supporting survival in migrating ...embryonic cells and ...embryonic cells differs from that of unipotent PGCs (Kato et ...embryonic cells, differentiation-associated ... See full document
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Analysis of multi-lineage gene expression dynamics during primordial germ cell induction from human induced pluripotent stem cells
... obtain germ line cells from early hu- man embryos. Notably, in the last decade, generation of germ cells from pluripotent stem cells (embryonic stem cells, ESCs, and ... See full document
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Germ cells and germ cell transplantation
... 1997). Primordial follicles, in which the oocytes are arrested in the diplotene stage of first meiotic prophase, have been recovered from the neonatal mouse ovary and matured in vitro by appropriate hormone ... See full document
6
Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
... midline germ cell death at ...increased germ cell survival in the midline (Stallock et ...2). Germ cells (GFP+) in the ‘midline’ region (between the coelomic angles) and ... See full document
9
Identification of side population cells in mouse primordial germ cells and prenatal testis
... stem/progenitor cell types (Challen and Little, 2006) and relies on the activity of ATP-binding cassette (ABC) transporter su- perfamily, including multidrug resistance 1 (Mdr1a/1b, mouse; MDR1, human) and breast ... See full document
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Programmed cell death of primordial germ cells in Drosophila is regulated by p53 and the Outsiders monocarboxylate transporter
... gonads. Germ cell movements are not delayed, and the PGCs appear to respond to midline repulsive signals, separating into two bilateral ...in germ cells is able to suppress the effects of ... See full document
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Programmed cell death in mouse primordial germ cells
... (2002), first suggesting a role of MAP kinase in preventing PGC apoptosis via Kit show- ing that two potent MEK/MAPK inhibitors reduced the number of migratory PGC culture onto cell feeder layers producing ... See full document
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Alteration in Expression of Primordial Germ Cell (PGC) Markers During Induction of Human Amniotic Mesenchymal Stem Cells (hAMSCs)
... post-migratory germ cell decision-making in order to enter the meiosis or stop at the mitosis stage ...stem cells from different sources containing various ...stem cells were isolated from ... See full document
6
Differentiation of mouse primordial germ cells into female or male germ cells
... Mouse primordial germ cells (PGCs) migrate from the base of the allantois to the genital ...the first meiotic division in the ovary to become oocytes, while those in the testis become ... See full document
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Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles
... The Notch2 gene is expressed at high levels in granulosa cells, the somatic-cell lineage of the ovarian follicle. To assess whether Notch2 gene function is required for correct development of the ... See full document
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DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages
... Primordial germ cells (PGCs) are the founding population of cells that will ultimately give rise to the mature ...somatic cells (Fujiwara et ...can first be detected in the ... See full document
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