[PDF] Top 20 Profiling genome-wide DNA methylation
Has 10000 "Profiling genome-wide DNA methylation" found on our website. Below are the top 20 most common "Profiling genome-wide DNA methylation".
Profiling genome-wide DNA methylation
... reference genome [96–101] and methylation calling ...erence genome, and reads with both Cs and Ts can then be ...higher methylation levels ...reference genome and the read into Ts, and ... See full document
16
Genome-wide average DNA methylation is determined in utero
... DNA was extracted from buccal cells in the PETS, from adipose tissue in the MuTHER and from whole blood in the other studies. Each study measured DNA methylation using the HM450 assay and performed ... See full document
9
A genome-wide DNA methylation study in colorectal carcinoma
... bp) and 148 were hypomethylated (median distance from TSS 308 bp) in CRC. Hypomethylated loci were slightly more distal from TSS (Mann-Whitney U test, p < 0.001). On average, 42.8% of the variation in the ... See full document
16
Establishing an analytic pipeline for genome-wide DNA methylation
... the methylation differences at this CpG ...tory genome annotation data provided by the ENCODE [70] and Roadmap Epigenomics [71] projects, an alterna- tive and/or complimentary approach is to evaluate the ... See full document
10
Genome-wide analysis of DNA methylation in bronchial washings
... of DNA methylation [10]. It modulates DNA methy- lation by the following these mechanisms: (i) recruiting DNA methyltransferase 1 (DNMT1) to damage sites during DNA repair; (ii) ... See full document
9
DNA methylation study of fetus genome through a genome-wide analysis
... a DNA- binding transcription factor which may regulate gene ex- pression, morphogenesis and ...development. Methylation of this gene may result in the loss of its ... See full document
8
A genome wide survey of DNA methylation in hexaploid wheat
... For mapping analyses in this study, rather than mapping directly to the 6-Mb Agilent bait probe sequences, un- less otherwise stated, data were mapped to the baits plus any surrounding contiguous DNA sequence that ... See full document
15
Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy
... family. DNA methylation analysis by high-resolution genome-wide DNA methylation array identified a decrease in CpGs with 0 – 10 % methylation and 80 – 95 % ... See full document
6
Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer’s disease
... We first employed linear regression to delineate disease- specific effects on methylation between cases and controls at each of the 461,272 autosomal CpGs. Linear models were developed to account for various ... See full document
14
Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies
... of DNA methylation associated with imprinted genes can be illustrated by the data for three known imprinted genes, GNAS, CDKN1C and MEST, for which multiple probes were present on the Infinium ... See full document
16
Genome-wide DNA methylation profiling shows a distinct epigenetic signature associated with lung macrophages in cystic fibrosis
... We were able to identify enrichment of hyper- or hypo-methylated loci to specific genomic contexts sug- gesting their importance for gene regulation. Hypo- methylated CpGs in CF subjects were enriched for puta- tive ... See full document
10
Methylation Abnormalities in Mammary Carcinoma: The Methylation Suicide Hypothesis
... novo methylation of tumor suppressor genes has been proposed as comparable or equivalent to inactivating mutations as a factor in ...thylation profiling in primary ...genomic methylation status of a ... See full document
15
DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer
... of DNA methylation patterns on bevacizumab efficacy. Methods: Genome-wide methylation profiling using the Illumina Infinium HumanMethylation450 BeadChip was performed in archival ... See full document
11
DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns
... with methylation data) with a mean age at initial recruitment of 70 ...collected. Genome-wide DNA methylation was analyzed using the Illumina Human Methylation 450K Beadchip ... See full document
8
Tackling the methylome: recent methodological advances in genome-wide methylation profiling
... the genome size obstacle (the mouse genome is ...from DNA digestion with the MspI restriction enzyme, which has a recognition site (CCGG) abundant in CpG islands ...size-selected DNA ... See full document
7
Nivolumab in chemotherapy-resistant cervical cancer: report of a vulvitis as a novel immune-related adverse event and molecular analysis of a persistent complete response
... a genome- wide DNA methylation analysis (Infinium Methylation EPIC, Illumina) and compared the methylation pattern by a combined filtering and dimension reduction ap- proach [12, ... See full document
7
Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C
... specific methylation “epi-signature” resulting from loss of function mutations in the KDM5C gene that can be used to diagnose males with X-linked intellectual disability and asymptomatic female ...unique ... See full document
11
Genome-wide epigenomic profiling for biomarker discovery
... in DNA methyla- tion and DNA demethylation, respectively, and EZH2, which is part of the polycomb repressive complex 2 (PRC2) complex that trimethylates lysine 27 on histone 3 (H3K27me3) ...promoter ... See full document
17
Genome Wide Characterisation of DNA Methylation in an Invasive Lepidopteran Pest, the Cotton Bollworm Helicoverpa armigera
... Genome Wide Characterisation of DNA Methylation in an Invasive Lepidopteran Pest, the Cotton Bollworm Helicoverpa armigera 1 Genome wide characterisation of DNA methylation in an invasive Lepidopteran[.] ... See full document
26
Integrated analyses of multi-omics reveal global patterns of methylation and hydroxymethylation and screen the tumor suppressive roles of HADHB in colorectal cancer
... of DNA de- methylation, a series of techniques have been developed to accurately differentiate cytosine methylation states, including hMeDIP-seq, oxBS-seq, and TAB-seq [14, 20, ...of ... See full document
13
Related subjects