[PDF] Top 20 Programming dynamic nonlinear biomolecular devices using DNA strand displacement reactions

... a nonlinear quasi sliding mode (QSM) controller can be developed using a set of chemical reactions inspired by the ultrasensitive behaviour exhibited by a covalent modification cycle (CMC) cascade ... See full document

... understanding strand displacement, it does not predict or explain the underlying biophysical mechanisms, nor can it easily be adapted to han- dle more complex structural variants or explain ... See full document

... chemical reactions may be readily implemented in DNA-based chemistry (see ...cal reactions can serve as a programming language for designing synthetic circuits based on DNA-based chem- ... See full document

... of nonlinear system theoretic operators such as multivariate polynomi- als, rational functions, and Hill-type ...linear dynamic systems in ...idealised reactions, ...chemical reactions into ... See full document

... implemented using enzyme-free, entropy driven DNA reactions has huge potential in the field of Synthetic ...two biomolecular feedback control systems, a linear PI controller and a biologically ... See full document

... domains using strand displacement have been explored in ...of strand displacement reactions: one toehold-inactivated strand could have its toehold activated via ... See full document

... or devices at a biomolecular level [1], ...embedded biomolecular feedback control circuits ...controllers using DNA within this framework has focussed on the design of linear ... See full document

... of nonlinear feedback controllers can be designed using idealized abstract chemical reactions and implemented via DNA strand displace- ment (DSD) ...a programming language for ... See full document

... Naturally reduced genome studies show the evolutionary preservation of genes that are involved in protein synthesis. 35 A core set of almost 100 genes that encodes the protein expression factors has been established. 31 ... See full document

... model using agents and to simulate the interactions of those agents in parallel to model the real phenomena on a system ...such dynamic properties as movement, velocity, acceleration, and ... See full document

... coli DNA polymerase (lanes 1 to 7) and bacterio- phage T4 DNA polymerase (lanes 8 to 14) on a poly(dA)- oligo(dT) ...distributive DNA polymerase, the average length of product increased as a func- ... See full document

... novel dynamic programming methodology to achieve global and adaptive suboptimal stabilization of uncertain nonlinear systems via online ...M-file programming. Key Words: Global adaptive ... See full document

... Today, adaptive control has been widely used in nonlinear parameterized systems (Chen et al., 2011). NNs have obtained many applications and have attracted a great deal of attention in RL due to their ability to ... See full document

... replicates its DNA), some of the some of the telomere is lost due to exonuclease telomere is lost due to exonuclease activity (i.e. ends are degraded). activity (i.e. ends are degraded). – Eventually little or no ... See full document

... the DNA molecule, we conduct the calculation according to the results obtained ...of DNA as a sample space,and selecting a sample of DNA ...use DNA molecular to compute Bayesian ... See full document

... T7 DNA poly- merase reveals the presence of a loop of 4 aa (residues 401– 404) within the DNA-binding groove; this loop is not present in other members of the DNA polymerase I ...T7 DNA ... See full document

... We then find that the I-V characteristics are gapped with a conductance gap on the order of 2 V, in good agreement with controlled STS experiments. The transport is dominated by HOMO conduction and this essentially ... See full document

... Hybridization experiments of the singlestranded DNA with isolated complementary strands of adenovirus type 5 DNA showed that this DNA hybridized only with the viral L-strand the strand w[r] ... See full document

... Analysis of in vitro reverse transcription reactions carried out by mutant virions showed that minus-strand strong-stop DNA was formed but did not efficiently translocate to the 3' end o[r] ... See full document

... In the chaos theory, when the initial conditions have a little changes, the future state of system can be caused extremely large difference through the continuous amplification. In numerous continuous chaos system, ... See full document