[PDF] Top 20 Protective effects of naringin in indomethacin-induced gastric ulcer in rats

... as indomethacin (IND) are extensively used to decrease pain and reduce fever in inflammatory diseases as rheumatoid arthritis and ...side effects such as gastrointestinal toxicity and can cause peptic ... See full document

... to rats in a similar model proved effective as ...The protective effects of selenium was proved in testicular IR ...treated rats showed almost normal ...and naringin showed similar ... See full document

... Gastric ulcer is one of the serious problems and diseases for many of patients that cause a lot of sufferings to these patients and its cause may be either due to stress or by using of a lot of ... See full document

... of gastric mucosa, congestion of submucosal edema associated with hemorrhage ...and gastric pits have also been noted ...well, gastric mucosa fell away into a deep ulcer whose base contained ... See full document

... the effects of IND and or GEN on gastric secretion, studies were performed in different groups of pylorus ligated rats as described by Rajashekhara et ... See full document

... these effects, prostaglandin protects the mucosa from ulceration (Ananya et ...hydrophobic protective lining of the mucus gel layer leading to ulcerations (Al-Harbi et ...inhibited indomethacin ... See full document

... NSAID induced gastric ulcers. Similarly, indomethacin (IND) is widely approved in medical prac- tice as being an NSAID; it shows exceptional efficiency in the treatment of fever, pain and ... See full document

... Peptic ulcer is a major health hazard both in terms of morbidity and ...side effects and higher ...gastro protective and antiulcer efficacy of Mollugo oppositifolia plant extract in the alcohol ... See full document

... the rats prevented the formation of gastric lesions induced by HCl/ethanol, indomethacin/HCl-ethanol, indomethacin and pylorus ...ulcers induced by acetic acid and ... See full document

... ing indomethacin treatment of the rat stomach was reduced by lansoprazole and lycopene, an antioxidant substance; however, SOD levels were increased under these conditions ...to gastric mucosa after ... See full document

... beneficial effects through their ability to block cyclooxygenase, thereby inhibiting prostaglan- din production ...particular, indomethacin causes gastric ero- sions with increased lipid peroxidation ... See full document

... the gastric adenocar- cinoma (GA) and paired non-neoplastic mucosa tissues, one of the upregulated proteins identified in GA was trans- gelin which was validated by immunohistochemistry and western blotting ... See full document

... experimental gastric ulcer in rats resulting in severe gastric mucosal ...harmful effects either through direct generation of reactive metabolites, including free radical species that ... See full document

... that indomethacin could increase gastric lipid peroxidation therefore generate reactive oxygen ...damage gastric cells. This was reflected by decreased amount of DNA in gastric mucosa which, ... See full document

... Peptic ulcer is a common illness in internal medicine which affects a considerable number of people worldwide ...of gastric ulcers ...adverse effects, such as arrhythmias, impotence, gynecomastia, ... See full document

... employing indomethacin, ethanol and pylorus ligation ulcer ...in gastric volume, total acidity, free acidity, ulcer index and increase in pH of gastric ...pylorus ulcer in the ... See full document

... against induced-ulcer in four different ...of ulcer that induced by aspirin in rat stomach and reduced ulcer index from ...that induced by 150mg/kg aspirin to ...that ... See full document

... Animals: Twelve week-old healthy Wistar rats (150- 200 g) of either sex procured from Indian Institute of Sciences Bangalore were used for this study. They are maintained under standard conditions (temperature ... See full document

... The leaf decoction of the study genus is used for treating uterine and other fluxes; lukewarm leaf juice is used as ear drops for fungal infections; leaves are astringent, refrigerant and also used to cure ulcers; stem ... See full document

... various gastric disorders including intestinal ...gastroprotective effects of Triphala formulations against experimental gastric ulcer in rats to substantiate its traditional ...claim. ... See full document