[PDF] Top 20 Proton pump inhibitors and acute kidney injury: a nested case–control study

... of acute kidney injury thought to result from an idiosyncratic, cell-mediated immunologic reaction ...in case-reports of PPI-induced AIN, the triad of symptoms was present in a minority of ... See full document

... this study is that it reflects daily clinical ...COX-2 inhibitors were conducted in relatively young, healthy ...Our study suggests that these may not be the patients who are especially at risk for ... See full document

... Our analysis revealed that younger patients might be more likely to develop AKI due to PPIs use than elderly patients. In older participants ($60 years old), PPIs use had no significant association with AKI, but a ... See full document

... of kidney diseases among patients using proton pump inhibitors (PPIs) have been ...of kidney diseases in patients with PPIs ...pool study-specific risk ...with kidney ... See full document

... of case–control data was used to investigate the association of treatment (exposure to PPI) with each outcome of interest [8]; onset of CKD and mortality, respectively, controlling for age, sex, race, GI ... See full document

... The AKI developed 2–5 days from admission. AKI was diagnosed in 61 patients (25.9%). Of these cases, 66.1% had Stage I disease whereas Stage II and Stage III disease were present in 12.9% and 21.0%, respectively. A ... See full document

... 4 case- control ...(Risk, Injury, Failure, Loss, End-stage renal disease) criteria [20] ( “ R ” stage: plasma creatinine levels ≥ ...1 study defined AKI as a greater than 25% rise in serum ... See full document

... The study enrolled 139 patients diagnosed with GERD by the gastroenterologist, among which two third were ...this study was in accordance with the results of the study conducted by Kiyotaka et ...our ... See full document

... Our study has several ...population-based study that characterized the risk of AKI associated with atypical antipsychotic drug ...our study explored potential reasons why AKI may develop from the ... See full document

... Risk, Injury, Failure, Loss, and End-stage (RIFLE) renal disease criteria in 2004, [11] the AKI Network (AKIN) criteria in 2007 [12], and the Kidney Disease Improving Global Outcomes (KDIGO) AKI criteria in ... See full document

... acids and glucose injections were administered for intravenous nutritional support. The blood pressure was controlled by urapidil hydrochloride injection pump point, and the urine volume by furosemide. The patient ... See full document

... Nevertheless, in most cases, hemodynamic or toxic actions seem to be insufficient in the pathogenesis of AKI [89]. The role of nonhemodynamic factors, such as dys- functional inflammatory cascades, oxidative stress, ... See full document

... cohort study had also evaluated the risk of adverse cardiovascular events while on a PPI and clopidogrel with pooled data from patients enrolled in 3 large health insurance ... See full document

... Proton pump inhibitors are commonly used drugs for treating acid peptic disorders like peptic ulcer, gastro oesophageal reflux disorders, NSAID induced mucosal injury, Zollinger Ellison ... See full document

... within about 1 week of discontinuation of PPI therapy. In cases of re-challenge, hypomagnesemia developed within a couple of weeks of re- initiation of PPI therapy. The patients generally presented with profound ... See full document

... this study is the fact that this is a retrospective ...no control group during the entire observation period, but we can show a sufficient length of control periods as seen in Figure 1 and Figure ... See full document

... prescribing proton pump inhibitor drugs (PPIs), (In 2006 PPI was the third most frequently prescribed drug in ...The study have included that general practitioners (GPs) prescribe PPIs irrationally ... See full document

... Case presentation: A 19-year-old woman was sent to the emergency room for taking 80 colchicine tablets (0.5 mg per tablet) 44 h previously. The main physical symptom was abdominal pain. Following ingestion, the ... See full document

... (Risk, Injury, Failure, Loss, End-stage kidney disease) classification to categorize the severity of AKI ...therapy. Acute lung injury (ALI) and acute respiratory distress syndrome ... See full document

... Abstract: There is a lack of consistent guidelines and consensus for the diagnosis of laryngopharyngeal refl ux (LPR). A therapeutic trial with a proton pump inhibitor (PPI) has been suggested to identify ... See full document