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[PDF] Top 20 Rapid screening of MDR TB using molecular Line Probe Assay is feasible in Uganda

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Rapid screening of MDR TB using molecular Line Probe Assay is feasible in Uganda

Rapid screening of MDR TB using molecular Line Probe Assay is feasible in Uganda

... from MDR-TB suspects for DST. Currently DST is performed using MGIT 960, but this comes with a number of chal- lenges related to the need for cold storage of specimens during transport and high level ... See full document

7

Rapid detection of Multi Drug Resistant- Tuberculosis using Line Probe Assay (LPA) in Sudan

Rapid detection of Multi Drug Resistant- Tuberculosis using Line Probe Assay (LPA) in Sudan

... Pulmonary TB patients were diagnosed for the first time while118 ...P- TB reflecting the active transmission of ...the molecular methods were highly consistent with the conventional culture and DST ... See full document

14

Frequency and patterns of second-line resistance conferring mutations among MDR-TB isolates resistant to a second-line drug from eSwatini, Somalia and Uganda (2014–2016)

Frequency and patterns of second-line resistance conferring mutations among MDR-TB isolates resistant to a second-line drug from eSwatini, Somalia and Uganda (2014–2016)

... in MDR isolates that are resistant to second line anti-TB drugs from eSwatini, Somalia and Uganda is high especially to FQs, implying that rapid molecular tests ...MTBDRplus/sl ... See full document

9

Course on Multidrug-Resistant Tuberculosis MDR-TB

Course on Multidrug-Resistant Tuberculosis MDR-TB

... routinely using molecular methods to rapidly diagnose drug ...the rapid turnaround time; disadvantages include the high cost, the low sensitivity for cer- tain drugs, the potential for false-positive ... See full document

220

A study on mutation in genes associated with rifampicin and isoniazid resistance in Mycobacterium tuberculosis complex using line probe assay

A study on mutation in genes associated with rifampicin and isoniazid resistance in Mycobacterium tuberculosis complex using line probe assay

... world’s TB cases. It is estimated that nearly 50% of the world’s burden of MDR-TB cases is in India and ...for TB diagnosis. Which play a major role in failure of TB control program in ... See full document

5

Combination of the MODS Assay with the SensititreTM MYCOTB Plate for Rapid  Detection of MDR  and XDR TB

Combination of the MODS Assay with the SensititreTM MYCOTB Plate for Rapid Detection of MDR and XDR TB

... http://dx.doi.org/10.4236/jtr.2014.23012 How to cite this paper: Salee, P., Harrison, L., Dionne, K., McArthur, C. and Parrish, N. (2014) Combination of the MODS Assay with the Sensititre™ MYCOTB Plate for ... See full document

6

Evaluation of genotype MTBDRplus VER 2 0 line probe assay for the detection of MDR TB in smear positive and negative sputum samples

Evaluation of genotype MTBDRplus VER 2 0 line probe assay for the detection of MDR TB in smear positive and negative sputum samples

... sputum of patients who had treatment failure or relapse in a routine outpatient setting in the study. In addition, in the study done in South Africa by Barnard et al. [22] to evaluate LPA with Xpert MTB/RIF from smear ... See full document

8

Line Probe Assay Protocol

Line Probe Assay Protocol

... that line probe assay protocol described ...changes: line probe assay protocol described here they are both ...a line probe assay a single strip assay ... See full document

9

Evaluation of the AID TB Resistance Line Probe Assay for Rapid Detection of Genetic Alterations Associated with Drug Resistance in Mycobacterium tuberculosis Strains

Evaluation of the AID TB Resistance Line Probe Assay for Rapid Detection of Genetic Alterations Associated with Drug Resistance in Mycobacterium tuberculosis Strains

... the line probe assay was shown to be capable of rapid genetic assessment of drug resistance in MGIT broth cultures, the results of which were in 100% agreement with those of DNA sequencing and ... See full document

7

Prospective evaluation of simply modified MODS assay: an effective tool for TB diagnosis and detection of MDR-TB

Prospective evaluation of simply modified MODS assay: an effective tool for TB diagnosis and detection of MDR-TB

... diagnosed TB patients’ sputum ...highly TB-burdened area with limited ...routine TB control program service at 16 district hospitals and a regional ...for TB diagnostic pipe lines following ... See full document

8

Molecular characterization of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates identifies local transmission of infection in Kuwait, a country with a low incidence of TB and MDR-TB

Molecular characterization of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates identifies local transmission of infection in Kuwait, a country with a low incidence of TB and MDR-TB

... active TB disease, > 80% of all TB cases and > 95% of DR-TB and MDR-TB cases occur among expa- triate patients, mainly originating from TB endemic countries of South Asia ... See full document

13

Screening and preventive therapy for MDR/XDR-TB exposed/infected children (and adults)

Screening and preventive therapy for MDR/XDR-TB exposed/infected children (and adults)

... • Close contacts of MDR-TB patients should receive careful clinical follow-up for at least two years. • If active disease is present or develops, prompt initiation of MDR-TB treatment [r] ... See full document

25

Evaluation of Two Line Probe Assays for Rapid Detection of Mycobacterium tuberculosis, Tuberculosis (TB) Drug Resistance, and Non TB Mycobacteria in HIV Infected Individuals with Suspected TB

Evaluation of Two Line Probe Assays for Rapid Detection of Mycobacterium tuberculosis, Tuberculosis (TB) Drug Resistance, and Non TB Mycobacteria in HIV Infected Individuals with Suspected TB

... evaluating line probe assays in a known HIV-infected ...MTBDR line probe assay for rapid ...HIV-infected TB suspects, specifically in settings where rapid ... See full document

8

Line-probe assay and molecular typing reveal a potential drug resistant clone of Mycobacterium tuberculosis in Ethiopia

Line-probe assay and molecular typing reveal a potential drug resistant clone of Mycobacterium tuberculosis in Ethiopia

... 7%, respectively. Drug resistance of strains carrying the most prevalent spoligotype in Ethiopia - SIT149 - was further explored. Stratification by MIRU-VNTR identified one genotype with a high rate of drug resistance ... See full document

7

Validation of the GenoType® MTBDRplus assay for detection of MDR TB in a public health laboratory in Thailand

Validation of the GenoType® MTBDRplus assay for detection of MDR TB in a public health laboratory in Thailand

... Two AFB-positive sputum specimens were confirmed as INH resistant by MGIT AST and sensitive by the Geno- Type ® MTBDR plus . We were able to obtain interpretable sequence data of the promoter region for inhA and katG for ... See full document

6

A commercial line probe assay for the rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta analysis

A commercial line probe assay for the rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta analysis

... of MDR- TB seen in routine clinical practice settings, even in high prevalence regions such as Estonia ...a TB laboratory would actu- ally receive, estimates of sensitivity and specificity may be ... See full document

9

Development and Evaluation of a Line Probe Assay for Rapid Identification of pncA Mutations in Pyrazinamide Resistant Mycobacterium tuberculosis Strains

Development and Evaluation of a Line Probe Assay for Rapid Identification of pncA Mutations in Pyrazinamide Resistant Mycobacterium tuberculosis Strains

... This assay can detect ...this assay does not have an internal control. In addition, this assay cannot correctly identify mixed PZA-resistant and -sus- ceptible ...This assay cannot detect ... See full document

6

ECDC GUIDANCE. Management of contacts of MDR TB and XDR TB patients.

ECDC GUIDANCE. Management of contacts of MDR TB and XDR TB patients.

... of MDR TB and XDR TB patients is controversial with little scientific evidence to support guideline ...of MDR TB contacts in European Union/European Economic Area (EU/EEA) revealed a ... See full document

28

Treatment Outcomes of Patients with Multidrug-Resistant Tuberculosis (MDR- TB) Compared with Non-MDR-TB Infections in Peninsular Malaysia

Treatment Outcomes of Patients with Multidrug-Resistant Tuberculosis (MDR- TB) Compared with Non-MDR-TB Infections in Peninsular Malaysia

... referral TB hospitals in peninsular Malaysia from January 2010 to January ...confirmed MDR-TB and XDR-TB cases at the selected study hospitals and as for non MDR TB, a simple ... See full document

9

A bacterial assay for rapid screening of IAA catabolic enzymes

A bacterial assay for rapid screening of IAA catabolic enzymes

... the molecular function of GH3, UGT and DAO enzymes during IAA inactivation [9, 14–16, 20, ...examined using high per- formance liquid chromatography (HPLC)- and thin-layer chromatography (TLC)-based ... See full document

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