[PDF] Top 20 Reactivity and selectivity in glycosylation reactions

... poor reactivity of 30 and to support this, picolyl protected 35 and 36 were prepared to disrupt this network by favoring intramolecular ...hydrogen-bonding. Glycosylation with C-4–OH acceptor 35 was as ... See full document

... (2) Analyses of reactivity selectivity relationships: (a) Stock, L. M.; Brown, H. C. Adv. Phys. Org. Chem. 1963, 1, 35–154. (b) Leffler, J. E.; Grunwald, E. Rates and Equilibria of Chemical ... See full document

... unusual reactivity of the nitrite-modified Wacker oxidation and the complexity of the catalytic system comprised of several co-catalytic species, we conducted a series of experiments aiming to deconvolute the ... See full document

... and selectivity. This theoretical study of chemical reactivity was carried out using the Density Functional Theory (DFT) method, at the B3LYP/6-31G (p) calculation ...these reactivity quantities ... See full document

... company is going to conduct testing on the compound, they cannot afford to waste 96% of their original materials. Thus, it is important for academic groups to discover as many different types of reactions and ways ... See full document

... donor reactivity study to date has been reported by Wong and co- workers, who quantified the reactivity of more than a hundred S-tolyl ...relative reactivity values (RRVs) were established in ... See full document

... substitution reactions of 3,3′-dmbp include chlorination that gives a mixture of 2-, 4- and 6-chloro-3,3′-dmbp with the 4-isomer being dominating [38], bromination and iodination that lead to the 4-halo ... See full document

... molecular reactivity and selectivity parameters for selected quinoxaline derivatives and to correlate some of the quantum chemical parameters with the experimental determined inhibition efficiency (%IE) ... See full document

... in glycosylation reactions, when used either as a donor or as an acceptor, 28,29 indicating that a postglycosyla- tion − oxidation strategy, in which the glycan backbone is made before the introduction of ... See full document

... although glycosylation reactions with oxathiane ketal sulfonium ions 4 are notable for the formation of glycosides with complete -stereoselectivity, 19,21 the resulting O-2 acyclic ketal formed in the ... See full document

... This strategy was successfully borne out with the phosphinooxazoline framework (Figure A6.4). Steric interaction between the equatorial P-aryl group and the allylic substituent controls the facial orientation of the ... See full document

... Typical samples for kinetic resolution consisted of the racemic substrate (1.0 mol dm'^), amine-borane catalyst (0.3 mol dm'^), DTBP (28% v/v) and t-butyl-benzene (0.2-0.4 mol dm'®) as an un reactive internal ... See full document

... and reactivity of these species depend on the position and configuration of the acyl ...of glycosylation reactions, employing a set of model nucleophiles of gradually decreasing nucleophilicity, we ... See full document

... The reactivity of aliphatic diamines on DHA is done by using DFT-based reactivity ...and selectivity sites of these compounds towards electrophilic and nucleophilic attacks, various global ... See full document

... probing glycosylation and other cognate reactions, including the development of cation clocks, mass spectrometry and 13 C NMR isotopic-labelling studies, and ... See full document

... of glycosylation of an amide nitrogen, using trimethylsilyl acetamide - an early demonstration of the potential utility of glycosyl sulfoxides as novel glycosyl ...the glycosylation of less reactive ... See full document

... Currently, there are few serologic test options for infections caused by fungi, and these tests aim to detect certain key fungal polysaccharides, such as galactomannan and glucan. However, to detect antigens, a large mi- ... See full document

... Dewar later went on to generalize his conclusions from the MIND0/3 studies of the Diets-Alder reaction and reported his view that ''Multi-bond reactions cannot normally be synchronous".3[r] ... See full document

... Chupakhin et al. also studied the ambident reactivity of primary and tertiary anilines with the N-methylacridinium ion (T). With tertiary anilines, a charge transfer complex was obtained with a broad absorption ... See full document

... Complexation and selectivity behaviour of an ionophore are evaluated in different ways. One method for evaluating the binding properties of the ionophore according to the ISE response is with a membrane with two ... See full document