[PDF] Top 20 Refractory pituitary adenoma: a novel classification for pituitary tumors

... and classification systems, and different clinicians use the term differently ...aggressive pituitary adenomas in the clinical setting ...increased pituitary adenoma aggressiveness [19], ... See full document

... normal pituitary tissues as well as distinctive overexpression of PKC in invasive PAs com- pared with noninvasive ones [35, ...as novel strategies for treating invasive PAs ... See full document

... between the tumor cells, as well as the tumor microenvironment, with other organs and systems of the body, which emphasizes the influence of tumors on the whole body. A number of studies have been done to ... See full document

... all pituitary tumors ...Organs Classification, The Ki-67 labeling index > 3% and p53 immunoreactivity might indicate that the tumor is more aggressive ...all pituitary carcinoma, but it is ... See full document

... brain tumors termed brain tumor- initiating cells (BTICs) [25, ...murine pituitary stem cells [1, 5, 7, ...which adenoma cells are cultured as tumor spheres in serum-free media or immuno- ... See full document

... Mortini et al. [14] showed that total resection rate of giant pituitary adenoma was 14.7%. Goel et al. [3] showed that the total resection rate was 29.65%, while Sinha et al. [15] showed a total resection ... See full document

... to rule out a coexisting intra- or juxtasellar aneurysm [18]. If there is abnormal signal in the PA or an unusual flow void signal, clinicians should be suspicious of a coincidental aneu- rysm within the adenoma. ... See full document

... and pituitary tumor volume, nor with cavernous sinus invasion, in our study we observed a sta- tistical association between headache presence and tumor size, optic chiasm compression, sellar destruction and ... See full document

... normal pituitary tissue (n=7), CD151 mRNA levels are increased in non-invasive pituitary adenomas (n=36) and further increased in invasive pituitary adeno- mas (n=24) (Figure ...normal ... See full document

... Background: Retinitis pigmentosa (RP) is one of the most severe hereditary retinal disorders with a worldwide prevalence reaching 1 in every 3000 – 5000 people and a total of almost one million affected individuals. RP ... See full document

... of pituitary adenomas in mice ...really novel, is the mechanism that leads to E2F1 activation by HMGA2: the E2F1 protein is not displaced from the pRB complex, but an increased acetylation that is dependent ... See full document

... trans-sphenoidal technique, which was initially reserved only for sellar lesions, has lead to a progressive possibility to access the skull base from the nose. This route allows midline access and visibility to the ... See full document

... the pituitary and adjacent skull base has under- gone rapid evolution in recent ...a pituitary ade- noma associated with obstructive hydrocephalus treated by endoscopic transnasal transsphenoidal ... See full document

... Ovarian hyperstimulation syndrome (OHSS) occurs mostly as an iatrogenic complication of as- sisted reproductive technology [1]. Classification of OHSS is based on clinical features and labo- ratory findings. ... See full document

... These adenomas do not exhibit any clinical or biochemical evidence of CD. The exact incidence rate of SCAs is unknown, which is reported to vary from 9% to 32.7% (3). Before surgery, they present in an identical way to ... See full document

... (TSH)beta. Expression of one or more of the anterior pituitary hormone genes was found in 12/14 (86%) of the patients with clinically classified nonfunctioning adenomas. Expression of one or more of the ... See full document

... In Oligodendroglial tumors the tissue usually crushes easily. They form evenly spread moderately to highly cellular smears. Smear would show discohesive relatively small tumor cell with uniform round slight dark ... See full document

... right with a retina and a papilla without any particular abnormality; But on the left there was a papillary edema. The field of vision was normal to the right. On the left, there was a temporal hemianopia. Magnetic ... See full document

... Right now, temozolomide is only used in cases, where other treatment options already failed. Due to the low rate of side effects, it seems warranted to discuss the initiation of temozolomide at an earlier point of time. ... See full document

... common tumors in the sellar or suprasellar areas. Pitu- itary tumors represent 10% to 15% of all intracranial tu- mors, with an annual incidence of ...coexisting tumors diffi- ...a pituitary ... See full document