[PDF] Top 20 Regulation of microRNA expression and function by nuclear receptor signaling
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Regulation of microRNA expression and function by nuclear receptor signaling
... myometrial expression of miR-200b/429, yet it also sig- nificantly increases ZEB1 mRNA and protein, a target of the miR-200 ...the expression of let-7, which targets PGRMC1 (proges- terone receptor ... See full document
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Microbial regulation of microRNA expression in the amygdala and prefrontal cortex
... appropriate regulation of miRNA expression within the amygdala and PFC is influenced by microbiota composition and activity and relies on the presence of a functional microbiota during critical windows of ... See full document
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Toll like receptor signaling in “inflammaging”: microRNA as new players
... ligands expression levels, both exogenous and endogen- ous, during cellular aging could contribute to such inflammation ...age-related expression of the TLR signaling pathway components have been ex- ... See full document
10
PKM2, function and expression and regulation
... MiR/miRNA: microRNA; MUC-1: Mucin-1; mTORC l: mammalian rapamycin target protein sensitive complex 1; NADH: nicotinamide adenine dinucleotide; NADPH: triphosphopyridine nucleotide; NEK2: never in mitosis ... See full document
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The role of miR-29b in cancer: regulation, function, and signaling
... aberrant expression of miR- 29b is common in the majority of human ...cancer regulation, function, and ...and signaling pathways, as well as to provide therapeutic implications for overcoming ... See full document
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Comprehensive evaluation of gene expression signatures in response to electroacupuncture stimulation at Zusanli (ST36) acupoint by transcriptomic analysis
... filaments Regulation of cytoskeleton rearrangement Skeletal muscle development Elongation-Termination Cell junctions Integrin-mediated cell-matrix adhesion Phagocytosis Cadherins EMT_Regulation of ... See full document
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Original Article MicroRNA-27a adjusts diabetic nephropathy patients and inhibits TGF-β/Smad signaling pathway
... complicated receptor signal transduction path- ways on cell surface in the manners of auto- crine and paracrine ...of microRNA- 27a suppressed apoptosis and caspase-3 activity,reduced TGFβ1 and p-Smad2 ... See full document
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A global microRNA screen identifies regulators of the ErbB receptor signaling network
... signaling pathways. Pathway topology information was re- trieved from Reactome, a manually curated and fast grow- ing pathway database, and combined with protein-protein interaction data. For the identification of ... See full document
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Effects of pamidronate disodium on the loss of osteoarthritic subchondral bone and the expression of cartilaginous and subchondral osteoprotegerin and RANKL in rabbits
... A signaling molecule composed of osteoprotegerin/ receptor activator of nuclear factor-κ B/RANK ligand (OPG/RANK/RANKL) has been described as critical in controlling osteoclast ...decoy ... See full document
12
Evolution and developmental expression of nuclear receptor genes in the ascidian Herdmania
... 169 nuclear receptor-containing clones derived from the PCR amplification of genomic DNA (55 clones) and cDNA (114 clones), identified eight unique consensus se- ...the nuclear receptor ... See full document
6
The roles of microRNAs in regulation of mammalian spermatogenesis
... The biogenesis of miRNAs is modulated at a few levels, including miRNA transcription, processing by Drosha and Dicer, RNA methylation, uridylation and adenylation (Fig. 1) [25–27]. The initial transcripts are termed the ... See full document
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Original Article MicroRNA30a inhabits tumor invasiveness and metastasis by targeting IGF1R in non-small lung cancer
... (Invitrogen). RNA was reverse transcribed using SuperScript First-Strand cDNA System (Invitr- ogen) according to manufacturer’s instructions. qRT-PCR analysis were conducted with Power SYBR Green (Takara). All protocols ... See full document
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Modulation of expression of the nuclear receptor NR0B2 (small heterodimer partner 1) and its impact on proliferation of renal carcinoma cells
... Nevertheless, even if the underlying mechanism for the antiproliferative effect in renal carcinoma cells has not been clarified, our findings in human kidney cells, and the results of others showing the tumor growth ... See full document
12
GABA suppresses neurogenesis in the adult hippocampus through GABAB receptors
... progenitors that generate proliferating neuroblasts, which exit the cell cycle before differentiating into granule neurons (Lugert et al., 2012). Neurogenesis is tightly regulated through a balance of NSC maintenance and ... See full document
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A Role of Swi/snf Complex in Aba-Dependent Drought Responsive Gene Expression in Arabidopsis Thaliana
... treatment, I next examined nucleosome positioning and occupancy at the ABI5 promoter using high-resolution MNase mapping (Chodavarapu et al., 2010; Rafati et al., 2011). I identified two well-positioned nucleosomes in ... See full document
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Transcriptional profiling of spiny lobster metamorphosis reveals three new additions to the nuclear receptor superfamily
... in expression between the three species examined, with the adult tis- sue distribution in ...tutive expression than in the larvae, where expression seems to be metamorphosis-specific in MAR1 and MAR3 ... See full document
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Regulation of ion homeostasis in plans and differential expression and function of arabidopsis thaliana nhx na+/h+ antiporters in the salt stress response
... other signaling proteins. Being a vital part of the SOS signaling pathway, the regulatory region of SOS2 has been shown to interact with SOS3 (Halfter et ...stress signaling (Ohta et ...the ... See full document
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Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet
... the transducers monitoring arterial pressure and renal blood flow were sampled at a rate of 100 samples/s for a period of 2 min, which usually was sufficient time to allow flow to return to its baseline value after each ... See full document
11
TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation
... Wnt signaling (98) and increased ex- pression of sclerostin (Wnt receptor antagonist) and Dkk1 ...BMP signaling to inhibit canonical Wnt sig- naling and therefore negatively regulate bone mass (99) ... See full document
17
Methotrexate and low dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor κβ expression in monocytes from patients with early rheumatoid arthritis
... Figure 4 Serum sRANKL and OPG levels in healthy donors and patients with RA at baseline and after MTX and low-dose prednisolone treatment. Both sRANKL and the sRANKL/OPG ratio increased in patients at baseline when ... See full document
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