[PDF] Top 20 Regulation and Modulation of Human DNA Polymerase δ Activity and Function
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Regulation and Modulation of Human DNA Polymerase δ Activity and Function
... Discontinuous DNA synthesis at the lagging strand in eukaryotes involves the synthesis of Okazaki fragments of ...Pol δ has been shown to have properties that are conducive to a role in Okazaki fragment ... See full document
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Epigenetic Regulation of Polymerase II Transcription Initiation in Trypanosoma cruzi: Modulation of Nucleosome Abundance, Histone Modification, and Polymerase Occupancy by O-Linked Thymine DNA Glucosylation
... the regulation of the RNA Pol I transcribed protein-coding genes within the telomeric gene cluster in ...epigenetic regulation of Pol II transcribed genes has been ... See full document
8
Biochemical and functional characterization of Plasmodium falciparum DNA polymerase δ
... Pol δ by forming a molecular sliding clamp and also plays a crucial role in DNA transactions where it acts as a scaffold for the recruitment and organization of protein complexes involved in both DNA ... See full document
10
Host and Strain Specific Regulation of Influenza Virus Polymerase Activity by Interacting Cellular Proteins
... of human host factors (enhancers) for optimal function in both assays ...to DNA damage or cellular stress (PARP1, the Ku70/86 complex, and ...virus polymerase (Fig. 1D). Viral ... See full document
10
Drug-Sensitive DNA Polymerase δ Reveals a Role for Mismatch Repair in Checkpoint Activation in Yeast
... bind DNA (Zou and Elledge 2003), we propose that MMR is needed primarily to produce ssDNA ...some DNA repair proteins have been observed to remain associ- ated with partially repaired DNA to reduce ... See full document
18
Pheasant virus DNA polymerase is related to avian leukosis virus DNA polymerase at the active site.
... The determinants shared by ALV and SNV DNA polymerases are different from those shared by APV DNA polymerase and ALV DNA polymerase, since SNV DNA polymerase cannot compete in a heterolo[r] ... See full document
13
Co expression and regulation of p53 and muc1 in human carcinomas
... 3 function is essential for the maintenance of the non-tumorogenic phenotype of ...suppressor activity of p53 is reported by growth arrest of cells, DNA repair, senescence, differentiation or by ... See full document
6
Translational regulation of herpes simplex virus DNA polymerase.
... Analysis of the transcript of the herpes simplex virus DNA polymerase gene provides evidence that polymerase expression is inefficient at the level of translation.. The kinetics of expre[r] ... See full document
9
Regulation of the Epstein-Barr virus DNA polymerase gene.
... Second, a 1.29-kb genomic fragment containing this region, when cloned upstream of the chloramphenicol acetyltransferase reporter gene, demonstrated promoter activity in lymphoid cells c[r] ... See full document
9
A Novel Role for Cet1p mRNA 5′-Triphosphatase in Promoter Proximal Accumulation of RNA Polymerase II in Saccharomyces cerevisiase
... phosphorylated-RNA polymerase II as a component of capping ma- chinery via Ceg1p for cotranscriptional formation of mRNA cap structure that recruits cap-binding complex (CBC) and protects mRNA from ...RNA ... See full document
18
A Role for DNA Polymerase δ in Gene Conversion and Crossing Over During Meiosis in Saccharomyces cerevisiae
... of DNA polymerase ␦, an essential DNA polymerase involved in genomic DNA ...in DNA replication, but displays a reduction in the length of meiotic gene conversion tracts and a ... See full document
10
Dissecting the Fidelity of Bacteriophage RB69 DNA Polymerase: Site-Specific Modulation of Fidelity by Polymerase Accessory Proteins
... measurements have been performed a few times before positioned near the Pol catalytic site at the end of helix but only for the overall rate of mutation in a reporter P of the fingers domain. This tyrosine is conserved ... See full document
16
Conserved Features of the PB2 627 Domain Impact Influenza Virus Polymerase Function and Replication
... performing activity assays in another chicken cell line (LMH) ...retained activity in chicken cells but displayed a significant reduction in human ...showed activity, the basic face mutants ... See full document
10
Irradiation and thyroid disease: dosimetric, clinical and carcinogenic aspects. Medicine. EUR 6713 EN
... Effect of TSH on,adenyl cyclase activity and intermediary metabolism of cold thyroid nodules and normal human thyroid tissue.. Regulation of function and growth in normal human thyroid t[r] ... See full document
261
Detection and analysis of diverse herpesviral species by consensus primer PCR
... Taq DNA polymerase incorporated incorrect bases into PCR products, as determined by the presence of different nucleotides at the same position in different ... See full document
6
Identification of a Mutant DNA Polymerase δ in Saccharomyces cerevisiae With an Antimutator Phenotype for Frameshift Mutations
... T4 DNA polymerase, is also present in the Saccharomyces cerevisiae DNA pol ...mutant DNA pol ␦ has a serine substitution in place of glycine at position ...447. DNA replication fidelity ... See full document
10
DNA polymerase activities in growing cells infected with simian virus 40.
... It is known that the activity of DNA polymerase-a is increased in the cytoplasm of cells entering the S phase 2, 3, 6, 7, 26, 29, and the enhanced level of DNA polymerase activity that i[r] ... See full document
9
Regulation of DNA Polymerase Exonucleolytic Proofreading Activity: Studies of Bacteriophage T4 “Antimutator” DNA Polymerases
... The locations of mutations to the exonuclease active center serves as a kinetic bar- that confer the antimutator phenotype suggest the possi- rier to the exonucleolytic proofreading path[r] ... See full document
7
Adenovirus DNA synthesis in vitro in an isolated complex.
... They did not report inhibition studies on DNA synthesis in intact complexes or on the DNA polymerase activity in extracts of the complexes, and it may be that the a-polymerase of the inf[r] ... See full document
5
Specific Serological Relationships Among Partially Purified DNA Polymerases of Avian Leukosis-Sarcoma Viruses, Reticuloendotheliosis Viruses, and Avian Cells
... For example, IgGRSV-RAV-0 did not neutralize TDSNV DNA polymerase activity, and IgG-TDSNV only slightly neutralized RSV-RAV-0 DNA polymerase activity, whereas RSV-RAV-0 DNA polymerase wa[r] ... See full document
10
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