[PDF] Top 20 Regulation of Septum Formation in Aspergillus nidulans by a DNA Damage Checkpoint Pathway
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Regulation of Septum Formation in Aspergillus nidulans by a DNA Damage Checkpoint Pathway
... Figure 8.—A branched regulatory pathway controls the cell types ( Fiddy and Trinci 1976; Harris 1997; timing of septum formation in predivisional hyphal cells. Dis- Kaminskyj and Hamer 1[r] ... See full document
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The Aspergillus nidulans snt Genes Are Required for the Regulation of Septum Formation and Cell Cycle Checkpoints
... the DNA damage checkpoint results in a of these mechanisms is the regulation of the cell cycle delay in septum formation (Harris and Kraus ...mitotic regulation is the ... See full document
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The Aspergillus nidulans uvsB Gene Encodes an ATM-Related Kinase Required for Multiple Facets of the DNA Damage Response
... In Aspergillus nidulans, uvsB and uvsD belong to the same epistasis group of DNA repair ...cycle checkpoint responses to DNA damage and incomplete ...the DNA damage ... See full document
10
Transcriptome Analysis of Aspergillus nidulans Exposed to Camptothecin-Induced DNA Damage
... tumor formation through redox stress resulting from increased pro- duction of reactive oxygen species (ROS) in mitochondria ...of DNA damage caused by ROS ...phosphate pathway that produces ... See full document
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DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide
... Figure 3. Effect of deletion of Chk2 on osteoblastic bone formation in Pthrp KI mice. (A) Representative longitudinal and cross sectional images of three-dimensional reconstructed distal ends of femurs and mid ... See full document
10
The csnD/csnE Signalosome Genes Are Involved in the Aspergillus nidulans DNA Damage Response
... to DNA damage that were investigated in this ...during checkpoint-dependent inhibition of septum formation, whereas the D csnD mutation does not; and (iv) the D csnD/ D csnE mutations ... See full document
13
Hypomorphic bimAAPC3 Alleles Cause Errors in Chromosome Metabolism That Activate the DNA Damage Checkpoint Blocking Cytokinesis in Aspergillus nidulans
... S-phase checkpoint con- trolling entry into mitosis (Figure 8B) or in the pathway controlling recovery from S-phase perturbation (data not shown), suggesting that the APC/C may be more intimately involved ... See full document
13
Regulation of Hyphal Morphogenesis and the DNA Damage Response by the Aspergillus nidulans ATM Homolog AtmA
... dependent regulation of hyphal ...the formation of mycelial colonies whose edge consists of well-spaced hyphae that grow outward in a linear manner (Figure ... See full document
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Spy1 Regulation of the DNA Damage Response; Checkpoint Activation and Cellular Senescence
... the formation of γ-H2AX foci ...as DNA damage-induced breaks, repair mechanisms like non-homologous end joining (NHEJ) are able to join any two dysfunctional chromosomal ends and lead to chromosomal ... See full document
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SepBCTF4 Is Required for the Formation of DNA-Damage-Induced UvsCRAD51 Foci in Aspergillus nidulans
... A. nidulans homo- logs of the spindle assembly checkpoint proteins Bub1p and Bub3p, respectively, and are required for meta- the anti-FLAG antibody and an additional epitope in ...defects nidulans ... See full document
12
Colorimetric Assay for Antifungal Susceptibility Testing ofAspergillus Species
... by Aspergillus species. The Aspergillus strains were incubated for 24 or 48 h and were then exposed for 1, 2, and 4 h to various concentrations of XTT, 200 (squares), 100 (triangles) and 50 (circles) g/ml, ... See full document
7
Aspergillus nidulans Ambient pH Signaling Does Not Require Endocytosis
... If so, endocytosis should be dispensable for signaling. In yeast, endocytosis involves ⬎ 30 proteins that are recruited in an orderly fashion to endocytic sites to mediate sequentially clathrin coat FIG 6 PalB is ... See full document
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Working hard for recovery: mitotic kinases in the DNA damage checkpoint
... DNA damage is frequently induced by radiation, geno- toxic chemicals, and metabolic byproducts, posing enor- mous threats on genomic ...Upon DNA damage, the cell must activate the DNA ... See full document
8
The Activation of ATR in Response to Double-Stranded DNA Breaks
... SANT DNA-binding domain, which in conjunction with the adjacent SLIDE domain is required to mediate the substrate recognition and chromatin remodeling activities of ISWI 161,162 ...The regulation of ISWI ... See full document
101
Discovery of a family of γ aminobutyrate ureas via rational derepression of a silent bacterial gene cluster
... conserved DNA sequences in the sgnR-sgnL and gbnR-sgnH intergenic regions as well as in the promoter region of gbnA ...conserved DNA sequences are proposed to be binding sites for GbnR ...putative ... See full document
6
Regulation of bone formation by baicalein via the mTORC1 pathway
... Total RNA was isolated from cultures with TRIzol reagent (Life Technologies, Grand Island, NY, USA) according to the manufacturer’s protocol. After MC3T3-E1 cells were incubated in differentiation medium for 14 days, ... See full document
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Diverse Regulation of the CreA Carbon Catabolite Repressor in Aspergillus nidulans
... Furthermore, regulation of CreA is thought to occur via the removal of ubiquitin molecules from the protein that leads to active CreA, a process that may be mediated by the CreB-CreC deubiquitination (DUB) complex ... See full document
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Cloning of the DNA repair gene, uvsF, by transformation of Aspergillus nidulans.
... More recently, this has been achieved by complementation of mutants using co- transformation of Aspergillus with wild-type library DNA in plasmid vectors that contain [r] ... See full document
9
Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC -deficient cells
... of DNA damage and the DNA repair ...the damage and repair aspects helps to more accurately interpret how individual alkylating agents induce ...the DNA damage response (DDR) ... See full document
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Fanconi Anemia FANCM/FNCM-1 and FANCD2/FCD-2 Are Required for Maintaining Histone Methylation Levels and Interact with the Histone Demethylase LSD1/SPR-5 in Caenorhabditis elegans
... FA pathway via FNCM-1 at stalled replication forks, we examined the localization of SPR-5 and factors acting in the FA pathway by ...FA pathway at stalled DNA replication forks, analogous to ... See full document
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