[PDF] Top 20 <p>Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma</p>
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<p>Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma</p>
... and P-values less than ...of B7-H3 expression levels with clinicopatho- logical characteristics, the chi-square or Fisher ’ s exact test was appropriately ...and B7-H3 ... See full document
10
B7-H3 is a new cancer-specific endothelial marker in clear cell renal cell carcinoma
... of tumor cells that stained positive for B7-H3 were quantified in 10% ...of cells staining positive were scored negative. In addition, B7-H3 expression in the ... See full document
7
Original Article B7-H3 in combination with regulatory T cell is associated with tumor progression in primary human non-small cell lung cancer
... Abstract: B7-H3 belongs to the co-inhibitory B7 family and plays an important role in the adaptive immune response in regulating T ...malignancies, B7-H3 is reported to be ... See full document
9
High Immune Response Rates and Decreased Frequencies of Regulatory T Cells in Metastatic Renal Cell Carcinoma Patients after Tumor Cell Vaccination
... low/negative Foxp3 + CD3 9 + cells in patient ...stable Foxp3-expressing nTregs in the patient cohort did not dif- fer from healthy ...sponding T cells before and after vaccination ... See full document
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Expression and significance of B7-H3 and Tie-2 in the tumor vasculature of clear cell renal carcinoma
... of B7-H3 in ccRCC angiogenesis and its correlation with the angiogenic factor Tie-2 and MVD, and the findings suggest that B7-H3 may promote tumor angiogenesis through the Tie-2 ... See full document
8
Foxp3 enhances HIF-1 target gene expression in human bladder cancer through decreasing its ubiquitin-proteasomal degradation
... in regulatory T lymphocytes [13]. Although its expression was first considered to be specific to this cell type, studies have demonstrated that Foxp3 protein is expressed as a marker ... See full document
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Tumor Necrosis Factor and Regulatory T Cells
... Treg cells were associated with severe liv- er injury, indicating that TNF-producing Treg cells are in- volved in the process of immune-mediated liver injury during AHA ...Treg cells from AHA ... See full document
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B7-H3 silencing by RNAi inhibits tumor progression and enhances chemosensitivity in U937 cells
... the cell proliferation-associated antigen Ki-67 (1:500 dilution) or a mouse monoclonal antibody to proliferating cell nuclear antigen (PCNA) (1:300 dilution) (Dako Corporation, Copenhagen, Denmark), ... See full document
13
Expression and clinical significance of multidrug resistance proteins in brain tumors
... of P-gp with caveolin-1 provide the morphological evi- dence of the association between P-gp and caveolin-1 in brain tumor endothelia and highlight the dynamic nat- ure of this ...and P-gp ... See full document
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Human beta-defensin 3 contributes to the carcinogenesis of cervical cancer via activation of NF-κB signaling
... various cells [6, 13, 17, ...cancer cells, the NF-κB pathway was clearly activated by overexpression of hBD3 (Figure ...hBD3 expression in tumor microenvironment was associated with ... See full document
12
Targeting the IDO1 pathway in cancer: from bench to bedside
... for tumor de- velopment, progression, and ...lung tumor growth and improved animal survival with reduced density of the underlying pulmonary blood vessels ...IDO1 expression positively correlates ... See full document
12
T Cells Bearing a Chimeric Antigen Receptor Against the Tumor Vasculature Destroy the Tumor Endothelium and Result in Tumor Regression
... CAR T cell-based immunotherapy for individuals with advanced ...CAR T cell therapy for the treatment of acute lymphocytic ...CAR T cells directed against the ganglioside, ...CAR ... See full document
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The role and significance of VEGFR2<sup>+</sup> regulatory T cells in tumor immunity
... Angiogenesis inhibitors are primarily divided into two categories: monoclonal antibodies targeting VEGF/ VEGFR2 and molecule inhibitors of tyrosine kinase (TKIs). Bevacizumab is a monoclonal antibody of VEGF-A, and it ... See full document
5
Expression of B7-H3 in Healthy and Diseased Gingival Samples: An Immunohistochemical Study.
... haematopoietic cells present in damaged tissue via CD40–CD40L interaction, which leads to the activation of the NF-kB family of ...presenting cells and suggests that it may provide crosstalk between ... See full document
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<p>Irradiation increases the immunogenicity of lung cancer cells and irradiation-based tumor cell vaccine elicits tumor-specific T cell responses in vivo</p>
... dendritic cells in mouse spleens, which may be followed by a higher antigen presenting ...of T-cells have various functions of pro- and anti-tumor ...CD4+ T helper cells, espe- ... See full document
11
<p>Dexamethasone inhibits the proliferation of tumor cells</p>
... a cell incubator culture Treat- ment: 24 hours later, the cells were adhered in the control group, and the medium was replaced with fresh DMEM high glucose and RPMI-1640 medium containing 10% ... See full document
14
Original Article Clinicopathologic features of clear cell papillary renal cell carcinoma: our experience of 11 cases
... intense staining with CK7, and a membranous distribution pattern with CAIX. Vimentin (Vim) and paired box gene 8 (PAX8) are also positive in most cases, while CD10 and TFE-3 are nega- tive. In this study, an ... See full document
5
Cell culture study on the cytotoxic effects of “Cureit” a novel bio available curcumin anti cancer
... of tumor cells, including breast carcinoma, colon carcinoma, renal cell carcinoma, hepatocellular carcinoma ... See full document
5
Current Progress in CAR-T Cell Therapy for Solid Tumors
... CAR-T cells traffick to the tumor sites To bind to their target proteins on the surface of tumors, CAR-T cells first need to traffick to tumor ...for T cell ... See full document
13
The coexpression and clinical significance of costimulatory molecules B7-H1, B7-H3, and B7-H4 in human pancreatic cancer
... The B7 family of molecules has been suggested to be a valu- able marker of the prognosis of various human ...between B7-H1, B7-H3, and B7-H4 and survival time for patients with ... See full document
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