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[PDF] Top 20 Repair of Topoisomerase-Mediated DNA Damage in Bacteriophage T4

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Repair of Topoisomerase-Mediated DNA Damage in Bacteriophage T4

Repair of Topoisomerase-Mediated DNA Damage in Bacteriophage T4

... m-AMSA-induced repair product ...with T4 origin ori(34)] or pAC1000 and pBS5 (lanes 3–4 and 7–8; without origin) were infected with T4 strain K10, and m-AMSA was added where indicated 6 min after ... See full document

10

Coordination of DNA Ends During Double-Strand-Break Repair in Bacteriophage T4

Coordination of DNA Ends During Double-Strand-Break Repair in Bacteriophage T4

... double-strand-break repair (DSBR) proposes that each end of a double-strand break (DSB) is repaired independently by initiating extensive semiconser- vative DNA replication after strand invasion into ... See full document

12

SEQUENCE AND TRANSCRIPTS OF THE BACTERIOPHAGE T4 DNA REPAIR GENE uvsY

SEQUENCE AND TRANSCRIPTS OF THE BACTERIOPHAGE T4 DNA REPAIR GENE uvsY

... T h e amino acid composition deduced from the DNA sequence and the direct amino acid analysis of purified gp UvsY (T. KONIGSBERG, personal communication) indicate that the [r] ... See full document

19

Properties of the nonlethal recombinational repair x and y mutants of bacteriophage T4. II. DNA synthesis.

Properties of the nonlethal recombinational repair x and y mutants of bacteriophage T4. II. DNA synthesis.

... When chloramphenicol was added at 8 min postinfection and label incorporation was measured at 15 min, the increased "rescued" DNA synthesis observed in mutant-infected cells retained its[r] ... See full document

13

Repair of Double-Strand Breaks in Bacteriophage T4 by a Mechanism That Involves Extensive DNA Replication

Repair of Double-Strand Breaks in Bacteriophage T4 by a Mechanism That Involves Extensive DNA Replication

... First, the dsb induces a repair reaction that is directly coupled to extensive plasmid replication; the repaired/replicated product is in the form of long plasmid concatemers.. Seco[r] ... See full document

14

Role of gene 59 of bacteriophage T4 in repair of UV-irradiated and alkylated DNA in vivo.

Role of gene 59 of bacteriophage T4 in repair of UV-irradiated and alkylated DNA in vivo.

... Our conclusion is based on the following results: i T4amC5 gene 59 is sensitive to both UV irradiation and MMS treatment; ii the results of alkaline sucrose gradient sedimentation of int[r] ... See full document

12

A New Epistasis Group for the Repair of DNA Damage in Bacteriophage T4: Replication Repair

A New Epistasis Group for the Repair of DNA Damage in Bacteriophage T4: Replication Repair

... The increased UV sensitivity caused by amA453 is additive to that caused by mutations in both the T4 excision repair (denV) and recombination repair (uvsWXY) systems, suggesting[r] ... See full document

13

Host- and Phage-Mediated Repair of Radiation Damage in Bacteriophage T4

Host- and Phage-Mediated Repair of Radiation Damage in Bacteriophage T4

... Escherichia coli str-ains Desi-nation Genotype with respect to repair B Wild B.,-, H/r30R uCvr-e vr-e H s30R uvrA res* R15 N1071 N1072 N1 252 Source Wild UV", X-ray sensitive Radioresist[r] ... See full document

11

Structural analysis of bacteriophage T4 DNA replication: a review in the Virology Journal series on bacteriophage T4 and its relatives

Structural analysis of bacteriophage T4 DNA replication: a review in the Virology Journal series on bacteriophage T4 and its relatives

... The T4 gp30 protein (gi: 5354233, NP_049813) is best known as T4 DNA ligase, a 487 residue ATP-dependent ...ligase. DNA ligases repair nicks in double-stranded DNA containing 3’ ... See full document

17

Bacteriophage T4 Mutants Hypersensitive to an Antitumor Agent That Induces Topoisomerase-DNA Cleavage Complexes

Bacteriophage T4 Mutants Hypersensitive to an Antitumor Agent That Induces Topoisomerase-DNA Cleavage Complexes

... Relationships between uvsX, uvsW, and mh The UvsXY recombination repair pathway is likely responsi- ble for repair of DNA damage resulting from mAMSA- induced topoisomeras[r] ... See full document

10

Initiation of bacteriophage T4 DNA replication and replication fork dynamics: a review in the Virology Journal series on bacteriophage T4 and its relatives

Initiation of bacteriophage T4 DNA replication and replication fork dynamics: a review in the Virology Journal series on bacteriophage T4 and its relatives

... a DNA end can trigger a new replication fork by invading homologous DNA, there would seem to be no need to coordinate the processing of the two ends of a DSB - each could simply start a new replication fork ... See full document

16

Host-Mediated Repair of Discontinuities in DNA From T4 Bacteriophage

Host-Mediated Repair of Discontinuities in DNA From T4 Bacteriophage

... KOZINSKI of Human Genetics, University of Pennsylvania School of Medicine, Philadelphia, Department Pennsylvania 19104 Discontinuities of T4 DNA which are caused by excision of UV-damage[r] ... See full document

10

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1

... more DNA strand breaks than wild-type cells, following incu- bation with the Top1 poison CPT (Figure ...of DNA breaks than did wild-type DT40 cells, though this difference was not statistically significant ... See full document

10

The specificity of topoisomerase-mediated DNA cleavage defines acridine-induced frameshift specificity within a hotspot in bacteriophage T4.

The specificity of topoisomerase-mediated DNA cleavage defines acridine-induced frameshift specificity within a hotspot in bacteriophage T4.

... that most or all cleavage sites lead to frameshift mu- tation. Overall, cleavage in the hot- spot region was reduced compared to the wild-type sequence and cleavage specif[r] ... See full document

10

The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts

The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts

... to DNA that contains an 8-oxoG lesion, in the absence of a high affinity CUX1 binding site (Figure ...involving DNA, OGG1 and CUX1 (Figure 7A and ...of DNA to facilitate the recognition of 8-oxoG by ... See full document

14

Review on DNA damage, repair and DNA sequencing

Review on DNA damage, repair and DNA sequencing

... of DNA damage affects of the double helix; that is, the bases themselves are chemically ...RNA, DNA usually lacks tertiary and therefore damage or disturbance does not occur at that ...level. ... See full document

6

Injection of Ultraviolet-Damage-Specific Enzyme by T4 Bacteriophage

Injection of Ultraviolet-Damage-Specific Enzyme by T4 Bacteriophage

... Details of the infections of the observations, considered with the results of the sympathetic breaking experiment previous experiment, clearly ruled out the possibility that wild-type ph[r] ... See full document

8

Properties of condensed bacteriophage T4 DNA isolated from Escherichia coli infected with bacteriophage T4.

Properties of condensed bacteriophage T4 DNA isolated from Escherichia coli infected with bacteriophage T4.

... The radioactivity was incorporated almost exclusively in host proteins, since a most of the label greater than 90% was incorporated before infection and b the electrophoretic analysis of[r] ... See full document

16

The DNA-Delay Mutants of Bacteriophage T4

The DNA-Delay Mutants of Bacteriophage T4

... 860-871 Copyright 0 1974 American Society for Microbiology The DNA-Delay Mutants of Bacteriophage T4 SIRAJ MUFTI' AND HARRIS BERNSTEIN Molecular Biology Program, Department of Microbiolo[r] ... See full document

12

Replicative Hybrid of T4 Bacteriophage DNA

Replicative Hybrid of T4 Bacteriophage DNA

... CsCl density gradient analysis of extracted U intracellular DNA and the hybrid density moiety CLJ isolated 45 min after infection of heavy bacteria with CK light 32P-labeled bacteriophag[r] ... See full document

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