[PDF] Top 20 A REVIEW ON: OCULAR INSERTS A NOVEL DRUG DELIVERY SYSTEM

... sterilization, inserts are transferred into polyethylene bag with the help of forceps inside the sterilization chamber ...with inserts are analyzed for potency by UV spectrophotometer after suitable ... See full document

... enables delivery of high concentration of active ingredients through skin. Drug delivery can be modulated by altering alcohol: water or alcohol-polyol: water ... See full document

... A chemical added to a polymer to increase its flexibility is known as plasticizers. It reduces the forces of attraction between the polymer chain and keeps them further apart by getting in between them which makes the ... See full document

... targeting drug delivery ...the drug in a controlled and predictable ...this review article, application of nanosponges, its preparation methods and evaluation parameters have been ... See full document

... of drug delivery and sustained drug release, but further optimization is still required, depending on the route of administration, frequency of dosing and the mode of drug release, before such ... See full document

... To increase skin permeability, a number of different approaches has been studied, ranging from chemical/lipid enhancers to electric fields employing iontophoresis and electroporation to pressure waves generated by ... See full document

... of drug bearing active hydrogen atom and phospholipid bonded by the covalent ...of drug in vesicle, small size, amphiphilic nature prolong existence of drug in systemic circulation, reduces the ... See full document

... These inserts are formed by bio-erodible polymers ...solid inserts absorb aqueous tear fluid and gradually erode or ...the drug is slowly leached from hydrophilic matrix. After completion of ... See full document

... a novel topical ophthalmic delivery system of ...in ocular therapeutics is the attainment of an optimal concentration at the site of ...from ocular dosage forms is mainly due to the ... See full document

... a drug delivery point of view. Ophthalmic drug delivery is extremely interesting and highly challenging ...many novel formulations have been developed. Ocular insert is one of ... See full document

... Novel drug delivery systems (NDDS) are the key area of pharmaceutical research and ...conventional drug delivery systems have been designed to modulate the release a drug over an ... See full document

... recently ocular drug ...the ocular surface, minimizing the effect of natural eye clearance ...controlled drug delivery to provide drug therapeutic levels for a prolonged time at ... See full document

... Multi-arm Block Copolymers: Synthesizing multi -arm block copolymers can also be useful to overcome the stability problem of regular micelles. For instance, star-shaped or multi-armed micelles can be formed with an ... See full document

... SMEDDS are defined as mixtures of oils, co-solvents and surfactants, which is isotropic in nature and which spontaneously emulsify to produce fine oil-in- water emulsions when introduced into aqueous phase under mild ... See full document

... Bulk density and floating duration have been the main parameters to describe the adequacy of a dosage form’s buoyancy Although single density determination does not predict the floating force evolution of the dosage form ... See full document

... new drug delivery ...release drug delivery systems, coupled with the increasing expense in bringing new drug entities to market, has encouraged the development of new drug ... See full document

... in ocular delivery for various drug ...to, ocular surfaces, and release contents at optimal rates ...precorneal drug retention and drug bioavailability ...the drug ... See full document

... topical ocular application since of little measure, basic and cheap arrangement, can be sterilized effortlessly by filtration (Soukharev et ...as drug carrier, retention promoter, and moo surface pressure ... See full document

... the novel classes of drug delivery systems, ocular inserts, are gaining worldwide popularity, release drugs at a pre- programmed rate for extended period by increasing the precorneal ... See full document

... topical drug delivery of local as well as interiorly acting ...Ideal drug delivery system aims to provide loading and maintenance dose of drug while being within therapeutic ... See full document