Top PDF The role of angiopoietin-2 in experimental abdominal aortic aneurysm development
The role of angiopoietin-2 in experimental abdominal aortic aneurysm development
... and 2) to determine the feasibility of using FMO as a control in assisting to define the negative and positive boundary, and thus to facilitate the compensation ...
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Angiopoietin-2 attenuates angiotensin II-induced aortic aneurysm and atherosclerosis in apolipoprotein E-deficient mice
... unlike angiopoietin-1, has a complex role and dynamically regulates Tie2 in a context dependent manner 20,21 ...the aortic wall in the presence of AngII, an important regulator of the inflammatory ...
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The potential role of kallistatin in the development of Abdominal Aortic Aneurysm
... VE—vascular endothelial; VEGF-A—vascular endothelial growth factor-A; VEGFR-2—VEGF receptor-2. The blue arrow lines indicate promotional activity; the red stop lines indicate inhibiting activity. Figure ...
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Urocortin 2: an interesting role in human abdominal aortic aneurysm
... 98 infusion of UCN3 into sheep with experimental heart failure decreased plasma renin. 306 Renin has been reported to initiate the cascade of events leading to AII production, 307 therefore a change in renin ...
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The role of kinin receptors in abdominal aortic aneurysm
... AAA development and also provide a model to investigate other strategies which could limit the critical end stage of ...the role of kinin receptors using a mouse model applying these findings to patients ...
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Pathogenesis of abdominal aortic aneurysm the role of inflammation and proteolysis
... cular aortic repair is becoming the preferred method to treat patients who have an AAA ...AAA development are regularly researched and include inflammatory mediators that could indicate which aneurysms are ...
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Osteoprotegrin: a pathological role in human abdominal aortic aneurysm
... of development, stems from an incomplete understanding of its ...to aneurysm formation remain ...aneurysmal aortic wall are degradation and fragmentation of the medial extracellular matrix (ECM), and ...
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Current state of experimental imaging modalities for risk assessment of abdominal aortic aneurysm
... most experimental variables were rejected as a risk factor for AAA ...the abdominal aorta seems ...37 Abdominal aortic calcification has also been associated with vascular morbidity and ...the ...
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Resveratrol inhibits growth of experimental abdominal aortic aneurysm associated with upregulation of angiotensin-converting enzyme 2
... The role of extracellular signal-related kinase during abdominal aortic aneurysm ...mediated aortic profilin-1 expression, inflammation and peroxynitrite ...
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Adrenomedullin Does Not Contribute toward the Development of Abdominal Aortic Aneurysm in Mice
... and Eto, T. (1999) An Autocrine or a Paracrine Role of Adrenomedullin in Modulating Cardiac Fibroblast Growth. Cardiovascular Research, 43, 958-967. http://dx.doi.org/10.1016/S0008-6363(99)00122-4 [14] Kawai, J., ...
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Inhibition of microRNA 29b reduces murine abdominal aortic aneurysm development
... Medicine, 2 Department of Cardiothoracic Surgery, and 3 Division of Vascular Surgery, Stanford University School of Medicine, Stanford, California, ...a role in modifying abdominal aortic ...
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Fenofibrate and telmisartan in the management of abdominal aortic aneurysm
... central role in the regulation of blood pres- sure and electrolyte homeostasis, and is also capable of in- ducing an inflammatory response in the vascular wall ...stimulate aneurysm formation in mice [11, ...
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The Role of Transglutaminases in the Development of Abdominal Aortic Aneurysms
... and is the site of binding of the endogenous inhibitors of MMPs, the TIMPs.(Page- McCaw et al., 2007) The MMPs were initially named based on their observed function, location and substrate specificity however recently ...
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Cyclooxygenase-2 Inhibition Attenuates Abdominal Aortic Aneurysm Progression in Hyperlipidemic Mice
... causative role for increased SMC differentiation as a mechanism contributing to the effectiveness of COX-2 ...the abdominal aorta is detected in the smooth muscle layer of the ...the role of ...
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Matricellular protein CCN3 mitigates abdominal aortic aneurysm
... in disease initiation and progression are incompletely understood. Extracellular matrix proteins play an integral role in modulating vascular homeostasis in health and disease. Here, we determined that the ...
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Matricellular protein CCN3 mitigates abdominal aortic aneurysm
... in disease initiation and progression are incompletely understood. Extracellular matrix proteins play an integral role in modulating vascular homeostasis in health and disease. Here, we determined that the ...
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Clonal expansion of T cells in abdominal aortic aneurysm: a role for doxycycline as drug of choice?
... direct experimental evidence available that the observed effects of doxycycline on AAA are based on its inhibition of mitochondrial protein synthesis, the finding of Lu et ...
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Abdominal Aortic Aneurysm
... Two patients had suprarenal aneurysms and the other had a thoracoabdominal aneurysm, The cause of all the AAA may be attributed to atherosclerosis except for one [r] ...
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Osteoprotegrin: a pathological role in human abdominal aortic aneurysm
... population-based screening for AAA has met with limited enthusiasm. Two reasons for this are immediately clear: 1) most AAA detected in screening programs are too small to warrant repair, and, 2) there are no ...
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Consequences of screening in abdominal aortic aneurysm: development and dimensionality of a questionnaire
... improvement regarding men undergoing surveillance for AAA. For the present analysis we have collected cross-sectional data from men participating in AAA screening having a normal screening result or being diag- nosed ...
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