[PDF] Top 20 Role of sex hormone binding globulin as the early predictor for gestational diabetes mellitus

... Using this formula with 8% prevalence the required sample size is 100 patients. Data was collected from the research participants who were eligible for the study. Diagnosis of GDM was made on the basis of criteria ... See full document

... In the current study, we found women with GDM had significantly lower levels of SHBG concentrations com- pared to Non GDM women at 24–28 weeks of pregnancy. This finding is consistent with results from previous stud- ies ... See full document

... normal sex steroid physiology could play a role in the pathogenesis of type 2 diabetes ...(T2DM). Sex hormone binding globulin gene polymorphisms may be the cause of ... See full document

... genesis of T2DM at both genetic and pheno- typic levels [12]. Studies have shown that rs- 1799941 SNP is located at the 5’ terminal of the non-translated region (G > A) 8 nucleotides upstream of the translation ... See full document

... of gestation and who gave birth in the same hospital from January 1, 2006 to October 31, 2013. Pregnant women who underwent a two-step approach to diagnose GDM were included [7]. The exclusion criteria were as follows: ... See full document

... Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with onset during preg- nancy, is increasing ...2 diabetes (T2D), history of macrosomic babies, and a previous ... See full document

... setting, gestational age, screening procedure (one and/or two steps), diagnos- tic criteria for GDM, sample size, GDM cases, prevalence of GDM, odds ratio, relative risk of certain risk ...were gestational ... See full document

... in hormone-sensitive cancers and the re- sults revealed that rs6259 minor allele was associated with reduced risk of endometrial cancer in postmeno- pausal, but not premenopausal women ... See full document

... A total of 233 patients with GDM from Kayseri Training and Research Hospital between 2002 and 2012 were included in the study. This study was approved by the Kayseri Training and Research Hospital Ethics Committee. The ... See full document

... blood sugar level less than 40mg% in any infant regardless of gestational age, About 50% of the hypoglycemic babies may remain asymptomatic. The factor mainly protective against fetal hypoglycemia is the optimal ... See full document

... and diabetes complications are supported ...for gestational diabetes may provide new public health intervention strategies for the prevention of gestational diabetes and its adverse ... See full document

... for gestational diabetes mellitus ...American Diabetes Association, Canadian Diabetes Association, International Diabetes Federation, as well as PubMed, Web of Science, Embase, ... See full document

... that early GDM treatment could be associated with a play off between a reduced LGA rate but an increased NICU admission rate (largely associated with SGA for those treated from ...insufficient gestational ... See full document

... growth hormone, is a major contributor to the insulin-resistant state seen in ...a role in ensuring that the fetus has an adequate supply of glucose by changing the maternal ener- gy metabolism from ... See full document

... that diabetes antedat- ing pregnancy can have severe adverse effects on fetal and neona- tal outcomes ...As early as in the 1940s, it was recognized that women who developed diabetes years after ... See full document

... that early age at me- narche is linked to higher fasting, one-, and two-hour plasma glucose levels, even after adjustment for con- founding factors [22, 30, ... See full document

... The liver produces plasma sex hormone–binding globulin (SHBG), which transports sex steroids and regu- lates their access to tissues. In overweight children and adults, low plasma SHBG ... See full document

... is also dangerous for women with SLE. Recently, more studies focus on the higher risks of pregnancy complica- tions in SLE patients, especially in patients with the existence of autoantibody positive, antiphospholipid ... See full document

... by sex hormone–binding glob- ulin (SHBG) in human ...for diabetes and heart ...ligand binding but causes abnormal glycosylation and inefficient secretion of ... See full document

... This study further reinforced previous findings that intraperitoneal administration of high doses of ALX in male rats induce type-1 diabetogenic conditions, which leads to reproductive complications such as reduced ... See full document