[PDF] Top 20 The role of long noncoding RNAs in human T CD3+ cells

... Noncoding RNAs (ncRNAs) are regulatory RNA molecules that do not code for proteins even though they affect and regulate a range of biologic ...interfering RNAs (siRNAs) and Piwi- interacting ... See full document

... lncRNAs including ANRIL have been shown to have a strong association with ECM protein-coding genes and are important regulators of fibrosis (30). Apart from binding of transcription factors to the promoters of the ... See full document

... mononuclear cells of 113 de novo AML patients, miR-19b overexpression had more fre- quently occurred and high miR-19b expression had a higher frequency of mutations of U2AF1 and IDH1/2 genes and associated with ... See full document

... It has been reported that a few miRNAs, such as miR-23 [101], miR-27 [101], miR-155 [102], and miR-132 [103], can promote CNV (Table 1). These miRNAs are significantly upregulated in the choroidal tissue of the rodent ... See full document

... It was reported that functions of lncRNAs can be inferred by coexpression analysis and their genome loca- tions [48, 49]. In NMR genome, we performed coex- pression analysis of lncRNAs with PTSGs-NMR and four HA-related ... See full document

... (Figure 1B). Accumulating evidence indicates that ncRNAs play a pivotal role in posttranscriptional and gene expres- sion regulation. For example, the circRNAs circ-EIF3J and circ-PAIP2 combine with the U1 snRNP ... See full document

... functional role of T-UCRs during neuronal differentiation ...481 T-UCRs, it was reported that 32 T-UCRs showed significant differential expression during retinoic acid (RA) induced neural ... See full document

... DLBCL cells, possibly through the PI3K/AKT/NF- κ B ...in human hepatocellu- lar carcinoma, 51 is also involved in the pathogenesis of ...important role in modulating cell proliferation and the cell ... See full document

... a role in mitochondria-mediated ...(RCC) cells apoptosis by activating the mitochondrial ...RCC cells was increased signifi- cantly after MEG3 ...key role in maintaining the homeostasis of ... See full document

... that long noncoding RNAs (lncRNAs) could act as either oncogenes or tumor suppressor genes in various cancers depending on their ...possible role of lncRNAs and their expres- sion on prognosis ... See full document

... regulatory role, especially since a subset called promoter-associated short (pas)RNAs has been found to interact with epigenetic factors such as Polycomb proteins (Kanhere et ... See full document

... expressed long noncoding RNAs (lncRNAs) and the potential role of lncRNA TUG1 in patients with chronic obstructive pulmonary disease ...HFL1 cells after TUG-siRNA transfection with ... See full document

... Long noncoding RNAs, RNA transcripts 200 nucleotides or longer that do not encode a functional protein, have been shown to regulate a wide variety of biological processes (Wapinski and Chang 2011; Li ... See full document

... the role of ncRNAs in CP, as discussed in this review and also summarized in ...stellate cells and their mediation of subsequent events leading to the disease ...newer noncoding RNAs, mostly ... See full document

... − MALAT1 (Metastasis associated lung adenocarcinoma transcript 1; also known as NEAT2: nuclear-enriched abundant transcript 2) is a nuclear lncRNA, located in the chromosome 11q13, initially re- ported to be ... See full document

... a human cell line (Tripathi et ...cancer cells (Gutschner et ...regulatory role for Malat1 in gene transcription (Zhang et ...between human and fish (Ulitsky et ... See full document

... Noncoding RNAs are a diverse group of transcriptional outputs of the mammalian genome without protein-coding ...coding RNAs participate in a multitude of processes coor- dinating gene expression ... See full document

... VHL-mutant RCC cell yet promoting the growth of VHL-normal RCC cell [57]. Decreases of lncRNAs such as NBAT-1 (neuroblastoma associated transcript-1) [58] and CASC2 [59] (cancer suscepti- bility candidate 2) are ... See full document

... small noncoding RNAs ex- pressed in normal CD4 ⴙ T cells compared to cells transformed with human T-cell leukemia virus type 1 (HTLV-1), the causative agent of adult ... See full document

... hiF-T: human induced fibroblast; HSC: hepatic stellate cell; HUVEC: human umbilical vein endothelial cell; kb: kilobase; lncRNA: long noncoding RNA; logLR: log-likelihood ratio; LOX: ... See full document