[PDF] Top 20 Role of resistin in diet induced hepatic insulin resistance
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Role of resistin in diet induced hepatic insulin resistance
... Recombinant resistin. The entire open reading frame (ORF) of resis- tin were cloned into pFM1, which contains an internal ribosome entry site followed by the ORF of GFP as previously described (19). Stably ... See full document
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Role of Resistin in Inflammation, Obesity and Type2 Diabetes mellitus
... human resistin in relation to obesity have shown higher serum resistin levels in obese subjects compared with lean subjects (39,28), which positively correlated with the changes in BMI and visceral fat area ... See full document
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Critical role of stearoyl CoA desaturase–1 (SCD1) in the onset of diet induced hepatic insulin resistance
... the rates of glucose infusion required to maintain euglycemia were markedly lower in OF rats compared with control rats fed a stan- dard chow (SC) diet (7.9 ± 0.7 versus 15.4 ± 0.2 mg/kg/min; P < 0.01) when SCR ... See full document
11
Hypothalamic resistin induces hepatic insulin resistance
... that resistin mRNA and protein are both present in mouse hypothalamus (33, 34) and that resistin activates a certain subset of hypothalamic neurons in vitro ...controlling hepatic glucose homeostasis ... See full document
10
Probing the role of stearoyl CoA desaturase–1 in hepatic insulin resistance
... important role in many diseases of altered cellular metabolism including obesity, insulin resistance, and ...the role of SCD1 in liver metabolism it is nec- essary to explore SCD1 deficiency ... See full document
5
Spexin alleviates insulin resistance and inhibits hepatic gluconeogenesis via the FoxO1/PGC-1α pathway in high-fat-diet-induced rats and insulin resistant cells
... control diet (Supplementary ...plasma insulin concentrations were significantly increased and were approximately ...the insulin concentrations in the HFD-fed rats, while no obvious changes were ... See full document
15
Adipocyte JAK2 mediates growth hormone–induced hepatic insulin resistance
... induce insulin resistance ...with insulin resistance ...increased insulin sensitivity outcomes (55–58). One of the many actions of insulin is to inhibit adipose tissue lipolysis ... See full document
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Exercise training performed simultaneously to a high-fat diet reduces the degree of insulin resistance and improves adipoR1-2/APPL1 protein levels in mice
... with insulin resistance ...enhanced insulin action on the skeletal muscle glucose transport system, reduced hormonal stimulation of hepatic glucose production, improved blood flow to skeletal ... See full document
9
The effect of N-stearoylethanolamine on plasma lipid composition in rats with experimental insulin resistance
... of insulin resistance (IR), induced by prolonged high fat diet with high content of saturated fats was used to investigate the effect of N-stearoylethanolamine (NSe) on the composition of free ... See full document
9
Original Article Correlation of resistin expression in maternal serum and subcutaneous adipose tissue with insulin resistance in gestational diabetes mellitus
... secreted insulin of islet beta cells ...of insulin secretion is limited, so the increase of insulin is not enough to offset the pregnancy-induced IR and blood glucose is increased from the ... See full document
7
Correlation between brain neurotransmitters and insulin sensitivity: Neuro-preservative role of resveratrol against high fat, high fructose-induced insulin resistance
... Insulin resistance (IR) is a major public health problem that can lead to many dangerous medical disorders and early ...(HFHF) diet experimentally induced-IR in rats. IR was induced by ... See full document
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Inflammation is not a contributing factor in the development of insulin resistance in diet induced obesity in rats
... Both insulin resistance and inflammation are complex disease states that involve a number of highly controlled signalling pathways [18, 19, 43, 53, 56, 96, 100, 164, 199, ...is induced in ... See full document
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Insulin receptor Thr1160 phosphorylation mediates lipid induced hepatic insulin resistance
... Animals and diets. Mice received ad libitum access to food and water and were generated and housed in the Yale Animal Resources Center at 23°C under a 12-hour light/12-hour dark cycles (0700–1900h). Male mice were ... See full document
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No Dose Response Relationship in the Effects of Commonly Consumed Sugars on Risk Factors for Diabetes across a Range of Typical Human Consumption Levels
... fructose-induced insulin resistance has been previously shown in ...weight. Insulin resistance was measured using the Homeostasis Model Assessment (HOMA IR) on fasting measures and a ... See full document
12
High-throughput sequencing of small RNAs and analysis of differentially expressed microRNAs associated with high-fat diet-induced hepatic insulin resistance in mice
... that hepatic IR can be induced by long-time high-fat diet (HFD) ...with hepatic IR, high-throughput sequencing of small RNAs was performed and analyzed in the livers of normal diet (ND) ... See full document
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Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance
... promote hepatic lipogenesis because it provides unregulated amounts of lipogenic substrates acetyl-CoA and glycerol-3-phosphate ...of insulin, which then acti- vates genes involved in de-novo lipogenesis ... See full document
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Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet induced obese mice
... other insulin resistance- associated ...to hepatic de novo lipogen- esis in palmitate-treated human HuS-E/2 ...and insulin sensitivity, which may have potential for clinical application in ... See full document
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Hepatic CB1 receptor is required for development of diet induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
... Diet-induced obesity. Male and female mice (6–8 weeks old) were fed either regular mouse chow or a high-fat diet for 14 weeks. The high-fat diet con- tained 33.8% fat (59.9% of calories), ... See full document
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Macrophage migration inhibitory factor deficiency ameliorates high fat diet induced insulin resistance in mice with reduced adipose inflammation and hepatic steatosis
... plasma insulin levels increased following the HFD irrespective of genotype, however obese MIF 2/2 mice secreted significantly less insulin in response to glucose compared to obese WT mice (Figure ...of ... See full document
14
Activation of hypothalamic S6 kinase mediates diet induced hepatic insulin resistance in rats
... by insulin and nutrients leads to inhibition of insulin signaling via negative feedback input to the signaling factor ...against diet-induced obesity and enhances insulin sensitivity in ... See full document
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