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[PDF] Top 20 The role of structural genes in the pathogenesis of osteoarthritic disorders

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The role of structural genes in the pathogenesis of osteoarthritic disorders

The role of structural genes in the pathogenesis of osteoarthritic disorders

... Mutations in genes for type IX collagen result in MED. This clinically heterogeneous disorder is characterized by mild short stature and early-onset OA. In some families, splice- site mutations in COL9A2 and ... See full document

9

The role of PHD2 mutations in the pathogenesis of erythrocytosis

The role of PHD2 mutations in the pathogenesis of erythrocytosis

... the genes encoding the PHDs in patients with erythrocytosis has revealed heterozygous germline mutations only occurring in Egl nine homolog 1 (EGLN1, also known as PHD2), the gene that encodes ...results. ... See full document

20

<p>The Role of Selected Pro-Inflammatory Cytokines in Pathogenesis of Ischemic Stroke</p>

<p>The Role of Selected Pro-Inflammatory Cytokines in Pathogenesis of Ischemic Stroke</p>

... Ischemic stroke is the most common cause of disability in elderly people (over 65 years of age) and the third most common cause of death in the world. The World Health Organization estimates that one in six people ... See full document

16

Role of the extracellular matrix and growth factors in skull morphogenesis and in the pathogenesis of craniosynostosis

Role of the extracellular matrix and growth factors in skull morphogenesis and in the pathogenesis of craniosynostosis

... lar genetic studies identified a mutation in homeotic gene MSX2 as the first genetic defect in craniosynostosis type 2, also known as Boston type, (Muller et al., 1997). In Crouzon, Pfeiffer, Jackson- Weiss and Apert ... See full document

9

Glycoprotein Content of Duodenum in Induced Duodenal Ulcer in Aged Male Mice and Aloe Vera Gel

Glycoprotein Content of Duodenum in Induced Duodenal Ulcer in Aged Male Mice and Aloe Vera Gel

... The structural change in mucosubstance and concentration of glycoprotein played prominent role in pathogenesis of gastrointestinal disorders [1] includes peptic ulcer, colitis and colon ... See full document

5

&lt;p&gt;The Role Of Adiponectin, TNF-α And Glutathione In The Pathogenesis And Evolution Of Type 1 Diabetes&lt;/p&gt;

<p>The Role Of Adiponectin, TNF-α And Glutathione In The Pathogenesis And Evolution Of Type 1 Diabetes</p>

... Elevated serum levels of adiponectin in children, adolescents and young adults with type 1 diabetes and the impact of age, gender, body mass index and metabolic control: a longitudinal s[r] ... See full document

6

The Role and Functions of the Implementation Committee of the School in Improving the  Quality of Education

The Role and Functions of the Implementation Committee of the School in Improving the Quality of Education

... the role of the school Committee functions as the giver consideration (X 1), supporters (X 2), the controller (X 3), mediator (X 4) in improving the quality of ... See full document

9

&lt;p&gt;The Role of Toll-Like Receptors 2 and 4 in the Pathogenesis of Chronic Obstructive Pulmonary Disease&lt;/p&gt;

<p>The Role of Toll-Like Receptors 2 and 4 in the Pathogenesis of Chronic Obstructive Pulmonary Disease</p>

... turn, the lowered expression of TLR4 gene caused the suppression of the synthesis of IFN- γ , a key cytokine for differentiation and functioning of Th1 cells. It has been shown that TLR4/TRIF/IKK ε (IkB kinase ε )/TBK1 ... See full document

13

The Role of the Dumai City Government in the Use of Reducing Poverty

The Role of the Dumai City Government in the Use of Reducing Poverty

... Poverty in Indonesia is experienced in almost all regions of the archipelago, including the City of Dumai. Poverty in Indonesia in general and Dumai City in particular not only extends to one particular group of people, ... See full document

12

The role of homeotic genes in determining the segmental pattern of chordotonal organs in Drosophila

The role of homeotic genes in determining the segmental pattern of chordotonal organs in Drosophila

... The peripheral nervous system (PNS) of Drosophila embryos provides a useful set of landmarks for investigating homeosis. Visible cuticular structures are associated with some sense organs and a number of specific ... See full document

7

&lt;p&gt;Role of pseudohypoxia in the pathogenesis of type 2 diabetes&lt;/p&gt;

<p>Role of pseudohypoxia in the pathogenesis of type 2 diabetes</p>

... The concept of pseudohypoxia in adult-onset diabetes (so called type 2 diabetes) and its complications was fi rst brought up by Williamson et al in 1993 1 and has since garnered increasing attention in the fi eld of ... See full document

8

The role of calcium in the hatching of Globodera rostochiensis

The role of calcium in the hatching of Globodera rostochiensis

... hatch again suggests t h a t Ca2+ from outside the egg- shell is not responsible either for initiating hatching or for the subsequent emergence of many juveniles [r] ... See full document

10

&lt;p&gt;The role of circadian clock genes in tumors&lt;/p&gt;

<p>The role of circadian clock genes in tumors</p>

... clock genes is likely to result in aberrant c-Myc levels, which increases the risk of cancer ...Per genes and inhibit c-Myc; therefore, PERs can indirectly suppress c-Myc transcription by regulating ... See full document

16

Language of self-definition in the disorders of identity

Language of self-definition in the disorders of identity

... the role of the awareness and experience of one’s own body as the original anchors of the developing sense of ...the role of language on the body in shaping one’s identity: the so-called eating and feeding ... See full document

9

Unmet needs in the treatment of schizophrenia: the role of aripiprazole

Unmet needs in the treatment of schizophrenia: the role of aripiprazole

... inoltre, non si sono osservate differenze significative tra aripiprazolo, Pl e aloperidolo, per la maggior parte degli altri effetti indesiderati, tranne che per la sedazione/s[r] ... See full document

17

Role of mesenchymal stem cells in the pathogenesis of psoriasis: current perspectives

Role of mesenchymal stem cells in the pathogenesis of psoriasis: current perspectives

... 43 genes encoding Th1, Th2, and TH17 ...of genes encoding Th1 and Th17 cytokines than healthy ...the genes encoding Th2 cytokines IL-2, IL-4, IL-13B, IL-22, IL-27, TGF- β 1, CCL1, CXCL12, and CCL22 ... See full document

13

The role of self-help in the treatment of mild anxiety disorders in young people: an evidence-based review

The role of self-help in the treatment of mild anxiety disorders in young people: an evidence-based review

... anxiety disorders in children, adolescents, and young adults to prevent the widespread debilitating effects of such mental health problems and progression to more serious ...The role of support in the use ... See full document

12

The role of plant species and soil condition in the structural development of the rhizosphere

The role of plant species and soil condition in the structural development of the rhizosphere

... in increasing hydraulic contact and connectivity between neighbouring aggregates. Hence, understanding how plants influence the precise arrangement of soil around a root in terms of densification, gap forma- tion, and ... See full document

14

Understanding the genetic basis of morphological evolution: the role of homeotic genes in the diversification of the arthropod bauplan

Understanding the genetic basis of morphological evolution: the role of homeotic genes in the diversification of the arthropod bauplan

... these genes provide identity to a distinct body region - the abdomen (Vachon et ...these genes seem to be involved in changing the morphology and function of anterior trunk seg- ments from locomotory to ... See full document

9

&lt;p&gt;Lichen sclerosus: the role of oxidative stress in the pathogenesis of the disease and its possible transformation into carcinoma&lt;/p&gt;

<p>Lichen sclerosus: the role of oxidative stress in the pathogenesis of the disease and its possible transformation into carcinoma</p>

... important role in the maintenance and progression of in fl am- mation, is decisive in the pathophysiological mechanisms of several chronic and autoimmune in fl ammatory ... See full document

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